On the Binding Mode and Molecular Mechanism of Enzymatic Polyethylene Terephthalate Degradation

• Published in: ACS catalysis Vol. 13; no. 10; pp. 6919 - 6933
• Main Authors: Falkenstein, Patricia, Zhao, Ziyue, Di Pede-Mattatelli, Ania, Künze, Georg, Sommer, Michael, Sonnendecker, Christian, Zimmermann, Wolfgang, Colizzi, Francesco, Matysik, Jörg, Song, Chen
• Format: Journal Article
• Language: English
• Published: American Chemical Society 19.05.2023
• Subjects: trehalose glass; polyester hydrolases; enzyme−substrate interactions; plastic recycling; solid-state NMR; molecular dynamics; biocatalytic PET degradation

Enzymatic degradation of polyethylene terephthlate (PET) by polyester hydrolases is currently subject to intensive research, as it is considered as a potential eco-friendly recycling method for plastic waste. However, the substrate-binding mode and the molecular mechanism of enzymatic PET hydrolysis...