Catalyst-Free Synthesis of 2,4-Disubstituted‑1H‑imidazoles through [3 + 2] Cyclization of Vinyl Azides with Amidines

A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent yields.

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Bibliographic Details
Published inACS omega Vol. 2; no. 8; pp. 5235 - 5241
Main Authors Reddy, N. Naresh Kumar, Nageswara Rao, Sadu, Ravi, Chitrakar, Adimurthy, Subbarayappa
Format Journal Article
LanguageEnglish
Published American Chemical Society 31.08.2017
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