Viruses of Microorganisms

In this multi-authored volume, international experts review the genomics, ecology, comparative biology and biotechnological applications of these fascinating viruses. Chapters have extensive reference sections that should encourage readers to pursue each subject in greater detail. This unique refere...

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Main Authors Hyman, Paul, Abedon, Stephen T
Format eBook
LanguageEnglish
Published Norfolk Caister Academic Press 2018
Edition1
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Abstract In this multi-authored volume, international experts review the genomics, ecology, comparative biology and biotechnological applications of these fascinating viruses. Chapters have extensive reference sections that should encourage readers to pursue each subject in greater detail. This unique reference volume is a must-read for everyone working with VoMs, from the PhD student to the experienced scientist, in academia, the pharmaceutical or biotechnology industries and working in clinical environments.
AbstractList Viruses of microorganisms (VoMs) are the world's most abundant viruses for every known microbe and VoMs are usually described in terms of their hosts as algal viruses, bacteriophages, virophages, fungal viruses and protozoan viruses. A key feature of infection by VoMs is that they often kill the host. This allows VoMs to play a key role in modifying microbial communities and in nutrient cycling in various environments. When the host is itself a pathogen then VoMs may be exploited to create novel antimicrobial strategies. In fact phage therapy for a variety of antibiotic-resistant bacterial pathogens is currently at the clinical trial stage. When they don't kill the host, VoMs can still play important roles in the ecology and evolution of their hosts via various forms of virus-mediated horizontal gene transfer.
In this multi-authored volume, international experts review the genomics, ecology, comparative biology and biotechnological applications of these fascinating viruses. Chapters have extensive reference sections that should encourage readers to pursue each subject in greater detail. This unique reference volume is a must-read for everyone working with VoMs, from the PhD student to the experienced scientist, in academia, the pharmaceutical or biotechnology industries and working in clinical environments.
Author Hyman, Paul
Abedon, Stephen T
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Snippet In this multi-authored volume, international experts review the genomics, ecology, comparative biology and biotechnological applications of these fascinating...
Viruses of microorganisms (VoMs) are the world's most abundant viruses for every known microbe and VoMs are usually described in terms of their hosts as algal...
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SubjectTerms Microorganisms
Viruses
TableOfContents Introduction - an historical perspective on phage diversity -- Lessons from taxonomy -- Lessons from phage methods -- Lessons from infection biology -- Lessons from 'omics' -- Summary - how much diversity is out there, really? -- 8. Viruses of Domain Archaea -- Introduction -- Brief overview of archaeal virus history (and semantics) -- Hosts of archaeal viruses -- Synopsis of archaeal virus characteristics -- Categories of archaeal virus types -- Crenarchaeota viruses -- Euryarchaeota Viruses -- Conclusion -- 9. Fungal Viruses -- Introduction -- Biocontrol of chestnut blight: a pioneering case study on the biology of mycoviruses -- Mycovirus taxonomy -- Viral integration into fungal genomes -- Mycovirus ecology and dispersal -- Evolution of fungal viruses -- Conclusion and future prospects -- 10. Diversity of Viruses Infecting Eukaryotic Algae -- Introduction -- Diversity inferred from environmental nucleic acids -- Diversity of cultivated algal viruses -- Double-stranded DNA (dsDNA) viruses -- Single-stranded DNA (ssDNA) viruses -- RNA viruses -- Summary -- 11. Protozoal Giant Viruses -- Introduction -- Genetic classification of Mimiviridae and Marseilleviridae families -- Mimiviridae family -- Marseilleviridae family -- Pandoravirus -- Pithoviruses -- Faustovirus -- Mollivirus -- Kaumoebavirus -- Pathogenicity of mimiviruses and marseilleviruses -- Conclusion -- 12. The Virophage Family Lavidaviridae -- Introduction -- Virion structure -- Virophage genomics -- Conserved genes -- Non-conserved genes -- Diversity and taxonomy of virophages -- Virophages and satellite viruses -- The Lavidaviridae -- Evolutionary connections of virophages -- The virophage infection cycle -- The protist−virus−virophage triangle -- Conclusion -- Part IV: Technologies Involving Viruses of Microorganisms -- 13. Viruses of Microorganisms and Biotechnology -- Introduction
Intro -- Contents -- Preface -- Part I: Introduction -- 1. Viruses of Microorganisms: What are They and Why Care? -- Introduction -- VoM, VoMi, and VoMa -- What is a microorganism? -- UOPs and MOPs -- What are viruses of microorganisms? -- VoMs and biotechnology -- Overview of basic VoM life cycles -- Conclusion -- 2. Genomics of Viruses of Microorganisms -- Introduction -- Current methods -- Overview of the genomics of different types of viruses -- Higher order genomic relationships -- Take home message -- Part II: Ecology of Viruses of Microorganisms -- 3. Evolutionary Ecology of the Viruses of Microorganisms -- Introduction -- VoM abundance, biodiversity, and biogeography -- Population dynamics of VoMs and hosts -- VoM impact on host populations and communities -- VoM ecological adaptation -- VoM genome evolution -- VoM impact on host genetics -- VoMs as ecosystem modifiers -- Closing remarks -- 4. Viruses of Microorganisms in Soil Ecosystems -- Goals of this chapter -- The soil habitat -- Viral abundance in soils -- Viral diversity -- Ecological impacts of viral infection -- Viruses of Archaea -- Viruses of Fungi -- Cyanobacteria, algae, and diatoms -- Viruses of amoebae and protozoa -- Conclusions -- References -- 5. Marine Viral Metagenomics with Emphasis on Coral Microbiomes -- Introduction -- Single-gene surveys of viral diversity -- Metagenomics -- A primer on coral biology -- Metagenomic exploration of the coral virome -- The emerging picture of the coral virome -- Future of coral viral metagenomics -- Conclusion -- 6. Virus Interactions in the Aquatic World -- Introduction -- Virus interactions with hosts -- Interactions with environmental factors -- New and poorly studied environments or viral groups -- Concepts and models -- Conclusions -- Part III: Diversity of Viruses of Microorganisms -- 7. Bacteriophage Diversity
Phage display -- Phage biosensors -- Phage based vaccines -- Conclusions -- 14. Viruses as Biocontrol Agents of Microorganisms -- Introduction -- The 'pharmacology' of virus-mediated biocontrol -- Use of whole viruses as biocontrol agents -- Commercial development of bacteriophage-mediated biocontrol -- Use of virus products as biocontrol agents -- Conclusion -- 15. Methods and Technologies to Assess Viral Interactions in the Aquatic World -- Introduction -- Techniques to study virus and virus-host interactions -- Conclusions -- Current Books of Interest -- Index
Title Viruses of Microorganisms
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