Molecular Aspects of the Interaction with Gram-Negative and Gram-Positive Bacteria of Hydrothermal Carbon Nanoparticles Associated with Bac8c2,5Leu Antimicrobial Peptide

• Published in: ACS omega Vol. 7; no. 19; pp. 16402 - 16413
• Main Authors: Barzan, Giulia, Kokalari, Ida, Gariglio, Giacomo, Ghibaudi, Elena, Devocelle, Marc, Monopoli, Marco P., Sacco, Alessio, Greco, Angelo, Giovannozzi, Andrea M., Rossi, Andrea M., Fenoglio, Ivana
• Format: Journal Article
• Language: English
• Published: American Chemical Society 17.05.2022

Antimicrobial peptides (AMPs) are widely studied as therapeutic agents due to their broad-spectrum efficacy against infections. However, their clinical use is hampered by the low in vivo bioavailability and systemic toxicity. Such limitations might be overcome by using appropriate drug delivery syst...