An Efficient and Organic Solvent-Free Slurry Method for Cocrystal Synthesis: Using Betaine Deep Eutectic Solvents as Dual-Functional Solvents and Reactants

• Published in: Crystal growth & design Vol. 24; no. 18; pp. 7686 - 7694
• Main Authors: Dai, Xia-Lin, Yao, Yu-Hang, Zhen, Jian-Feng, Cao, Yue, Gao, Wei, Lu, Tong-Bu, Chen, Jia-Mei
• Format: Journal Article
• Language: English
• Published: American Chemical Society 18.09.2024

The cocrystal strategy has been widely applied in the development of solid chemicals due to its potential to achieve tailored properties. However, traditional cocrystallization heavily relies on organic solvents, posing environmental and health risks and limited efficiency due to unwanted solvate fo...