Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation on Reintubation and Postextubation Respiratory Failure in High-Risk Patients: A Randomized Clinical Trial

• Published in: JAMA : the journal of the American Medical Association Vol. 316; no. 15; pp. 1565 - 1574
• Main Authors: Hernández, Gonzalo, Vaquero, Concepción, Colinas, Laura, Cuena, Rafael, González, Paloma, Canabal, Alfonso, Sanchez, Susana, Rodriguez, Maria Luisa, Villasclaras, Ana, Fernández, Rafael
• Format: Journal Article
• Language: English
• Published: United States American Medical Association 18.10.2016
• Subjects: Aged; Airway Extubation; APACHE; Clinical outcomes; Critical Illness; Female; Heart Failure - therapy; High-Frequency Ventilation - methods; High-Frequency Ventilation - utilization; Humans; Intubation; Length of Stay; Male; Noninvasive Ventilation; Oxygen Inhalation Therapy - instrumentation; Oxygen Inhalation Therapy - methods; Oxygen Inhalation Therapy - utilization; Patient safety; Respiratory Insufficiency - etiology; Respiratory Insufficiency - prevention & control; Respiratory Insufficiency - therapy; Risk assessment; Risk Factors; Ventilation

IMPORTANCE: High-flow conditioned oxygen therapy delivered through nasal cannulae and noninvasive mechanical ventilation (NIV) may reduce the need for reintubation. Among the advantages of high-flow oxygen therapy are comfort, availability, lower costs, and additional physiopathological mechanisms....