Mizoroki−Heck Type Reaction of Organoboron Reagents with Alkenes and Alkynes. A Pd(II)-Catalyzed Pathway with Cu(OAc)2 as an Oxidant

• Published in: Organic letters Vol. 3; no. 21; pp. 3313 - 3316
• Main Authors: Du, Xiaoli, Suguro, Masahiro, Hirabayashi, Kazunori, Mori, Atsunori, Nishikata, Takashi, Hagiwara, Nobuhito, Kawata, Kentaro, Okeda, Takeaki, Wang, Hui Feng, Fugami, Keigo, Kosugi, Masanori
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 18.10.2001

In contrast to the Pd(0)-catalyzed mechanism by Uemura, Mizoroki−Heck type reaction of boronic acids is found to proceed under a Pd(II)-mediated pathway using a catalytic amount of Pd(OAc)2 in the presence of Cu(OAc)2 as an oxidant. Treatment of a variety of alkenes with boronic acids, boronates, an...