A Fluorescence Sensor for Pb2+ Detection Based on Liquid Crystals and Aggregation-Induced Emission Luminogens
Heavy metals, such as lead ions, are regarded as the main environmental contaminants and have a negative impact on human bodies, making detection technologies of lead ions critical. However, most existing detection methods suffer from time consumption, complicated sample pretreatment, and expensive...
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Published in | ACS applied materials & interfaces Vol. 13; no. 19; pp. 22361 - 22367 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
American Chemical Society
19.05.2021
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Subjects | |
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Abstract | Heavy metals, such as lead ions, are regarded as the main environmental contaminants and have a negative impact on human bodies, making detection technologies of lead ions critical. However, most existing detection methods suffer from time consumption, complicated sample pretreatment, and expensive equipment, which hinder their broad use in real-time detection. Herein, we show a new fluorescence sensor for detecting lead ions derived from liquid crystals doped with an aggregation-induced emission luminogen. The mechanism is based on the variation of fluorescence intensity caused by the disturbance of an ordered liquid crystal configuration in the presence of Pb2+, induced by DNAzyme and its catalytic cleavage. The proposed fluorescence sensor exhibits a low detection limit of 0.65 nM, which is 2 orders of magnitude lower than that previously reported in an optical sensor based on liquid crystals. The detection range of the Pb2+ fluorescence sensor is broad, from 20 nM to 100 μM, and it also selects lead ions from numerous metal ions exactly, resulting in a highly sensitive, highly selective, simple, and low-cost detection strategy of Pb2+ with potential applications in chemical and biological fields. This approach to designing a liquid crystal fluorescence sensor offers an inspiring stage for detecting biomacromolecules or other heavy metal ions by varying decorated molecules. |
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AbstractList | Heavy metals, such as lead ions, are regarded as the main environmental contaminants and have a negative impact on human bodies, making detection technologies of lead ions critical. However, most existing detection methods suffer from time consumption, complicated sample pretreatment, and expensive equipment, which hinder their broad use in real-time detection. Herein, we show a new fluorescence sensor for detecting lead ions derived from liquid crystals doped with an aggregation-induced emission luminogen. The mechanism is based on the variation of fluorescence intensity caused by the disturbance of an ordered liquid crystal configuration in the presence of Pb2+, induced by DNAzyme and its catalytic cleavage. The proposed fluorescence sensor exhibits a low detection limit of 0.65 nM, which is 2 orders of magnitude lower than that previously reported in an optical sensor based on liquid crystals. The detection range of the Pb2+ fluorescence sensor is broad, from 20 nM to 100 μM, and it also selects lead ions from numerous metal ions exactly, resulting in a highly sensitive, highly selective, simple, and low-cost detection strategy of Pb2+ with potential applications in chemical and biological fields. This approach to designing a liquid crystal fluorescence sensor offers an inspiring stage for detecting biomacromolecules or other heavy metal ions by varying decorated molecules. |
Author | Luo, Dan Du, Xiaoxue Zhao, Dongyu Liu, Yanjun Wang, Fei Gleeson, Helen F |
AuthorAffiliation | School of Physics and Astronomy Department of Electrical and Electronic Engineering School of Chemistry and Environment |
AuthorAffiliation_xml | – name: School of Physics and Astronomy – name: School of Chemistry and Environment – name: Department of Electrical and Electronic Engineering |
Author_xml | – sequence: 1 givenname: Xiaoxue surname: Du fullname: Du, Xiaoxue organization: School of Physics and Astronomy – sequence: 2 givenname: Yanjun orcidid: 0000-0001-8724-0434 surname: Liu fullname: Liu, Yanjun organization: Department of Electrical and Electronic Engineering – sequence: 3 givenname: Fei orcidid: 0000-0003-1871-1022 surname: Wang fullname: Wang, Fei organization: Department of Electrical and Electronic Engineering – sequence: 4 givenname: Dongyu surname: Zhao fullname: Zhao, Dongyu email: zhaodongyu@buaa.edu.cn organization: School of Chemistry and Environment – sequence: 5 givenname: Helen F orcidid: 0000-0002-7494-2100 surname: Gleeson fullname: Gleeson, Helen F email: h.f.gleeson@leeds.ac.uk organization: School of Physics and Astronomy – sequence: 6 givenname: Dan orcidid: 0000-0003-2117-0570 surname: Luo fullname: Luo, Dan email: luod@sustech.edu.cn organization: Department of Electrical and Electronic Engineering |
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Title | A Fluorescence Sensor for Pb2+ Detection Based on Liquid Crystals and Aggregation-Induced Emission Luminogens |
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