Correlation Between Flow Rate, Viscosity, Buffering Capacity, pH and Carries in Full and Mozaic Down Syndrome Children: A Study in Trisomy and Mozaic Type Down Syndrome

• Published in: Journal of International Dental & Medical Research Vol. 10; no. 2; pp. 343 - 349
• Main Authors: Kusuma, Herawati, Saptarini, Risti, Sasmita, Inne, Willyanti, S, Effendi, Sjarif Hidajat
• Format: Journal Article
• Language: English
• Published: Diyarbakir Ectodermal Dysplasia Group-Turkey 01.07.2017; Ectodermal Dysplasia Group - Turkey
• Subjects: Biochemistry; Children; Chromosomes; Dental caries; Dentistry; Down syndrome; Down's syndrome; Gene expression; Odontology; Oral hygiene; pH effects; Studies; Trisomy; Viscosity; saliva; Down Syndrome Full and Mosaic; carries
• ISSN: 1309-100X; 1309-100X

Down Syndrome (DS) is a genetical abnormality caused by the abnormal amount or structural chromosome 21. Children with DS are in/have a higher risk of dental caries that related to salivary composition. The aim of the study was to analyze the difference of flow rate viscosity, buffer capacity, salivary pH with caries in children with full trisomy and mosaic type DS and its correlation with caries. This was an analytic correlational design study. The subject was 15 DS children aged 5-18 years, consisted of 3 mosaic type and 12 full/ complete trisomy type. The research used nonstimulation of the saliva. The salivary flow rate was measured by the amount of collected saliva during 5 minutes, divided by the time to collect the saliva. Salivary viscosity was visually measured based on the amount of the bubbles and the flow ability when the glass was moved to leaning position, Buffering capacity was recorded through the scores of color changes on the test pad. Salivary pH was scored based on color changes of the strip test. Caries was analyzed using DMFT index and deft. Statistical differentiation test using U Mann-Whitney and Kendal Rank Correlation test to find out the correlation of salivary function and the occurrence of caries. The results showed there were significant differences of flow rate, viscosity, buffering capacity, salivary pH and the occurrence of caries between children with full trisomy and mosaic type DS, besides significant correlation between flow rate, viscosity, buffering capacity, salivary pH and dental caries in children with full type DS and slight correlation in mosaic type. It was concluded that there were significant differences of flow rate, viscosity, buffering capacity, salivary pH and carries between children with full trisomy and mosaic type DS.