Membrane Proteins: Structure, Function and Motion
Membrane proteins are essential for the diverse biological functions of the cells and intercellular communication in living organisms. With the recent developments in the methodologies, the research on membrane proteins has been undergoing a major transformation. In this informative book, the biolog...
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Language | English |
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Basel
MDPI - Multidisciplinary Digital Publishing Institute
2023
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Abstract | Membrane proteins are essential for the diverse biological functions of the cells and intercellular communication in living organisms. With the recent developments in the methodologies, the research on membrane proteins has been undergoing a major transformation. In this informative book, the biological and dynamic behaviour of membrane proteins are introduced, discussed, and reviewed by some of the leading researchers in the field. The main objective of this compendium is to present the recent research in the fundamental and advanced concepts and methodologies used for studying membrane proteins. Membrane protein purification and reconstitution, protein–lipid interaction, ion/substrate transport, conformational and functional dynamics, the interaction of infectious agents, cell death, and organelle morphology are among the topics that are covered. This reprint is intended for a broad range of novice and experienced scientists with different levels of experience, from biophysicists and biochemists to microbiologists, cell biologists, and physiologists. |
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AbstractList | Membrane proteins are essential for the diverse biological functions of the cells and intercellular communication in living organisms. With the recent developments in the methodologies, the research on membrane proteins has been undergoing a major transformation. In this informative book, the biological and dynamic behaviour of membrane proteins are introduced, discussed, and reviewed by some of the leading researchers in the field. The main objective of this compendium is to present the recent research in the fundamental and advanced concepts and methodologies used for studying membrane proteins. Membrane protein purification and reconstitution, protein–lipid interaction, ion/substrate transport, conformational and functional dynamics, the interaction of infectious agents, cell death, and organelle morphology are among the topics that are covered. This reprint is intended for a broad range of novice and experienced scientists with different levels of experience, from biophysicists and biochemists to microbiologists, cell biologists, and physiologists. |
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SubjectTerms | 1-stearoyl-2-arachidonoyl phosphatidylethanolamine (1-SA-2-ETE-PE or SAPE) AAA-type protease ADP/ATP carrier ADP/ATP carrier protein advanced mass spectrometry AKR2 alternating access mechanism amino acid transporter AMPA amyloid-beta peptides angulin-1 antimalarial drugs apoptosis Arabidopsis thaliana arachidonic acid Archaerhodopsin-3 ATP synthesis ATP-binding cassette (ABC) transporter band 3 Bax Bcl-2 family Betacoronavirus Bid binding affinity biphasic proton transport model C-type inactivation CA3-CA1 synapses CD81 CD82 cell-free gene expression cellular pH chemical fixation chemosensory chloroplast chloroplast outer membrane proteome chloroplast transit peptide chloroplast-targeting pathways conductance measurements in model membranes Coronaviridae cryo-electron microscopy cryo-EM cytochrome b5 cytochrome b5 reductase detoxification double electron–electron resonance Earth Sciences, Geography, Environment, Planning efflux pump assembly electron transfer embryo lethal endoplasmic reticulum ER-HMGR domain fatty acid anion transport ferroptosis flicker-noise spectroscopy fluorescence fluorescence microscopy FtsH metalloprotease function gangliosides Geography giant unilamellar vesicles heterologous expression high-pressure freezing HMG-CoA reductase HMGR HMGR vesicle homo-FRET HT-29/B6 cells hydrogen–deuterium exchange mass spectrometry immunity inflammation influenza virus fusion peptides integral membrane protein intermediate-tight epithelium leaf variegation lipid bilayer lipid peroxidation lipidomics lipid–protein interaction lipoxygenase structure long-chain fatty acid long-chain fatty acids LSR MD simulations MDCK C7 cells membrane membrane chaperone membrane diffusion membrane fluidity membrane fusion membrane lipid membrane mechanics membrane mimetic membrane mimetic systems membrane protein membrane protein oligomerization membrane protein structure and function membrane traffic mevalonate microdomain microfluidics mitochondria mitochondrial carriers mitochondrial transporter molecular docking molecular dynamics monosaccharide transporter (MST) multidrug and toxic compound extrusion (MATE) transporter multiscale modeling n/a native mass spectrometry neurodegeneration nitric oxide NMDA nutrient transport O2 and NO● binding mechanisms odorant receptor OEP80 oligomeric state OSER oxidative stress paracellular water transport pathogenesis peptide-membrane interactions peptidoglycan plastid biogenesis potassium channels pressure wave protein import protein intrinsic dynamics protein oligomerization protein thermal stability protein–protein interaction proton gradient proton transfer proton transport Pseudomonas purine nucleotide reactive oxygen species control red blood cells Reference, Information and Interdisciplinary subjects regulation and mechanism of proton transport Research and information: general resistance SARS-CoV-2 Schaffer collateral-CA1 synapses selectivity filter conformation signal anchored protein single particle detection single-molecule Förster resonance energy transfer single-molecule tracking small HSP steady-state and time-resolved fluorescence anisotropy stress adaptation stress response structure sucrose transporter (SUT) superoxide anion radical systems biology tail anchored protein tetraalkylammonium salts tetraspanins tight epithelium TOC complex transmembrane proteins tricellular tight junction tricellulin uncoupling uncoupling proteins vaccines β-barrel protein β-signal |
Title | Membrane Proteins: Structure, Function and Motion |
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