The Gut Microbiome Bench to Table
The influence of the gut microbiome on human health and disease has been established in recent years through advances in high-throughput DNA sequencing. The Gut Microbiome: Bench to Table presents a scientific introduction to this topic and analyzes the research on how the microbiome is affected by...
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| Main Author | |
|---|---|
| Format | eBook Book |
| Language | English |
| Published |
Boca Raton
CRC Press
2022
Taylor & Francis Group |
| Edition | 1 |
| Subjects | |
| Online Access | Get full text |
Cover
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Table of Contents:
- Role of the Gut Microbiota in Human Health and Disease Prevention -- Cardiovascular Disease -- Cultured Food Products -- Role of Cultured Products in Gut Microbiota Modulation -- Yogurt -- Milk Kefir -- Probiotic Fermented Milk -- Role of Cultured Beverages in Gut Microbiota Modulation -- Role of Fermented Vegetables in Gut Microbiota Modulation -- Effects of Phenolic Compounds on Gut Microbiota -- Conclusion -- References -- Chapter 6 Dietary Modulation of the Gut Microbiota by Prebiotics and Other Dietary Nutrients and Relevant Health Effect(s) -- Introduction -- Types of Prebiotics -- Carbohydrate Prebiotics -- Oligosaccharides -- Human Milk Oligosaccharides -- Polysaccharides -- Inulin -- Non-Carbohydrate Prebiotics -- Polyphenols -- Short-Chain Fatty Acids -- Metabolism of Nutrients by the Gut Microbiota -- Effect of Prebiotic on Immunity -- Prebiotics as Functional Foods -- Novel Prebiotic Formulations -- Food-Processing Effects on Probiotics and Prebiotics -- Factors That Influence Probiotic Viability -- Conclusion -- References -- Section III: T2-3 Effectiveness Trials in General Population and Regulatory Limitations -- Chapter 7 Gut Microbiota and Polyphenols: Discussing a Powerful Interplay and Its Effect on Health -- Introduction -- Overview of Polyphenols -- Classification and General Description -- Food Sources and Consumption -- Overall Metabolism/Bioavailability and Excretion -- Microbiota Metabolism of Polyphenols and Health Effects -- Gut-Derived Metabolites -- Health Effects of Polyphenol/Metabolite-Microbiota Interaction -- Considerations on Limitations of Human Studies, Novel Metabolic Approaches, and Metabotypes -- References -- Chapter 8 Diet, Obesity, and Gut Microbiome -- Introduction -- Gut Microbiota Formation and Characteristic -- Gut Microbial Composition, Dynamics, and Function
- The Metabolome and Microbiome Connection -- Host-Gut Microbiome Metabolic Interactions -- Microbiome - Diet Interactions -- The Gut Microbiome and Carbohydrate Metabolism -- General Considerations -- Simple Carbohydrates -- Complex Carbohydrates -- Nondigestible Polysaccharides - Fiber -- The Gut Microbiome and Fatty Acid Metabolism -- General Considerations -- Saturated Fatty Acids -- Polyunsaturated Fatty Acids (PUFAs) - Omega-3 and -6 (ω-3 and ω-6) Fatty Acids -- Short-Chain Fatty Acids -- The Gut Microbiome and Amino Acid Metabolism -- The Microbiome and Weight Change -- Future Perspectives -- References -- Chapter 4 Models for Researching the Gut Microbiome -- Introduction -- Computational Models -- In Vitro Models -- Fecal Batch Cultures -- Cell Culture -- Ex Vivo Models -- 3D Cell Culture -- Microfluidics Systems and the "gut chip" -- Simulator of the Human Intestinal Microbial Ecosystem (SHIME) -- Animal Models for Studying Gut Microbiota -- Insect Models -- Avian Models -- Murine Models -- Humanized Gnotobiotic Mice -- Porcine Models -- Zebrafish Model -- Fecal Microbiome Translocation Models -- Conclusion -- References -- Chapter 5 Dietary Modulation of Gut Microbiota by Cultured Products -- Introduction -- Biotherapeutic Properties of Cholesterol-Lowering Probiotics -- Concept of Probiotics -- Probiotic Microorganism -- Important Criteria in Selecting Probiotics -- Synthesis and Metabolism of Plasma Lipoprotein -- Cholesterol-Lowering of Probiotics -- Cholesterol-Lowering Effect Mechanisms -- Decongesting Bile Salts Using Bile Salt Hydrolyzing Enzyme -- Cholesterol Deposition with Conjugated Bile Salt -- Cholesterol Integration into Bacterial Cell Walls -- Lowering Serum Cholesterol by Probiotics -- Binding of Cholesterol -- Other Mechanisms -- Relationship between Nutrition and Gut Microbiota
- Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface -- Acknowledgments -- Editor -- Contributors -- Introduction -- Section I: T0 Benchwork, Including Techniques for Microbiome Studies -- Chapter 1 Tools and Resources Enabling Marker Gene-Based Microbiome Studies -- Introduction -- Historical Perspective of Microbiome Studies -- High-Throughput Sequencing Technologies -- 454 Pyrosequencing and Supported Oligonucleotide Ligation and Detection -- Illumina Platform -- Ion Torrent -- Long Read Sequencing Platforms -- SSU Reference Databases -- Greengenes -- SILVA -- Ribosomal Database Project -- EzBioCloud -- UNITE -- PR[sub(2)] -- Marker Gene Sequence Analysis Pipelines -- QIIME 1 and QIIME 2 -- mothur -- FROGS -- iMAP -- Recent Advances in Computational Tool Development -- Uniqueness of Marker Gene Survey Datasets -- Statistical Testing and Differentially Abundant Taxon Identification -- Balances and Microbial Signature Identification -- Tools for Network Analysis and Their Applications -- Web-Based Tools for Marker Gene Survey Data -- Conclusions -- Acknowledgments -- References -- Chapter 2 Phageome in Gut Microbiome -- The Origins and Roles of Phages, Phageome, and Its Composition in Human Gut Microbiota -- How Do Phages Shape the Human Gut Microbiota -- Phage Interaction with the Immune System -- Phageome and Health and Disease -- Phage-Based Therapy for Human Gut-Related Disease Is a Promising Approach to Control/Prevent Human Disease -- The Challenges of Phageome in Human Gut Microbiome, Perspectives, and Future Directions -- References -- Section II: T1 Preclinical Animal Studies, and Safety and Efficacy Trial in Humans -- Chapter 3 Microbiome and Nutrition - Why Do We Care? Discussing a Complex Relationship -- Introductory Remarks -- The Human Gut Microbiome
- Diversity and Composition of Gut Microorganisms Implicated in Host Health Maintenance -- Energy Metabolism and Gut Microbiota -- Gut Microbiota in Obesity -- Regulation on Host Metabolism -- Modulating Feed Behavior and Satiety -- Modulating Feed Behavior by Gut-Brain Axis -- Dietary Modulating Gut Microbiota Composition -- Dietary Styles in Relation to Gut Microbial Composition -- Macronutrients -- Carbohydrates -- Fat -- Protein -- Micronutrients -- Applications -- Clinical Therapeutics -- Probiotics and Prebiotics Intervention -- Conclusion -- References -- Chapter 9 Challenge, Future Research, and Influence in Food Science and Product Development -- Food and Gut Microbiome -- Microbiota Investigation Tools: Present and Future -- Culturomics: A New Approach to Investigate Human Gut Microbiota -- Role of Functional Food in Microbiota Modulation -- The Journey of Microbiome through Human Evolution -- References -- Index