Fluorine-Containing Block and Gradient Copoly(2-oxazoline)s Based on 2‑(3,3,3-Trifluoropropyl)-2-oxazoline: A Quest for the Optimal Self-Assembled Structure for 19F Imaging

• Published in: Biomacromolecules Vol. 22; no. 7; pp. 2963 - 2975
• Main Authors: Kaberov, Leonid I, Kaberova, Zhansaya, Murmiliuk, Anastasiia, Trousil, Jiří, Sedláček, Ondřej, Konefal, Rafal, Zhigunov, Alexander, Pavlova, Ewa, Vít, Martin, Jirák, Daniel, Hoogenboom, Richard, Filippov, Sergey K
• Format: Journal Article
• Language: English
• Published: American Chemical Society 12.07.2021
• Subjects: biocompatibility; composite polymers; copolymerization; fluorine; magnetism; micelles; signal-to-noise ratio; small-angle X-ray scattering; transmission electron microscopy

The use of fluorinated contrast agents in magnetic resonance imaging (MRI) facilitates improved image quality due to the negligible amount of endogenous fluorine atoms in the body. In this work, we present a comprehensive study of the influence of the amphiphilic polymer structure and composition on...