Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors
Hammond, Marlys, Washburn, David G., Hoang, Tram H., Manns, Sharada, Frazee, James S., Nakamura, Hiroko, Patterson, Jaclyn R., Trizna, Walter, Wu, Charlene, Azzarano, Leonard M., Nagilla, Rakesh, Nord, Melanie, Trejo, Rebecca, Head, Martha S., Zhao, Baoguang, Smallwood, Angela M., Hightower, Kendra, Laping, Nicholas J., Schnackenberg, Christine G., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Journal Article
Rhodium-Catalyzed Silylcarbocyclization (SiCaC) and Carbonylative Silylcarbocyclization (CO−SiCaC) Reactions of Enynes
Ojima, Iwao, Vu, An T, Lee, Seung-Yub, McCullagh, James V, Moralee, Andrew C, Fujiwara, Masaki, Hoang, Tram H
Published in Journal of the American Chemical Society (07.08.2002)
Published in Journal of the American Chemical Society (07.08.2002)
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Journal Article
Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4)
Brooks, Carl A, Barton, Linda S, Behm, David J, Eidam, Hilary S, Fox, Ryan M, Hammond, Marlys, Hoang, Tram H, Holt, Dennis A, Hilfiker, Mark A, Lawhorn, Brian G, Patterson, Jaclyn R, Stoy, Patrick, Roethke, Theresa J, Ye, Guosen, Zhao, Steve, Thorneloe, Kevin S, Goodman, Krista B, Cheung, Mui
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Journal Article
Optimization of a Novel Series of TRPV4 Antagonists with In Vivo Activity in a Model of Pulmonary Edema
Hilfiker, Mark A, Hoang, Tram H, Cornil, Johan, Eidam, Hilary S, Matasic, Daniel S, Roethke, Theresa J, Klein, Michael, Thorneloe, Kevin S, Cheung, Mui
Published in ACS medicinal chemistry letters (14.02.2013)
Published in ACS medicinal chemistry letters (14.02.2013)
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Journal Article
Synthesis and SAR of potent LXR agonists containing an indole pharmacophore
Washburn, David G., Hoang, Tram H., Campobasso, Nino, Smallwood, Angela, Parks, Derek J., Webb, Christine L., Frank, Kelly A., Nord, Melanie, Duraiswami, Chaya, Evans, Christopher, Jaye, Michael, Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
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Journal Article
Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists
Thompson, Scott K., Washburn, David G., Frazee, James S., Madauss, Kevin P., Hoang, Tram H., Lapinski, Leahann, Grygielko, Eugene T., Glace, Lindsay E., Trizna, Walter, Williams, Shawn P., Duraiswami, Chaya, Bray, Jeffrey D., Laping, Nicholas J.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
Hammond, Marlys, Patterson, Jaclyn R., Manns, Sharada, Hoang, Tram H., Washburn, David G., Trizna, Walter, Glace, Lindsay, Grygielko, Eugene T., Nagilla, Rakesh, Nord, Melanie, Fries, Harvey E., Minick, Douglas J., Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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Journal Article
Improving the developability profile of pyrrolidine progesterone receptor partial agonists
Kallander, Lara S., Washburn, David G., Hoang, Tram H., Frazee, James S., Stoy, Patrick, Johnson, Latisha, Lu, Qing, Hammond, Marlys, Barton, Linda S., Patterson, Jaclyn R., Azzarano, Leonard M., Nagilla, Rakesh, Madauss, Kevin P., Williams, Shawn P., Stewart, Eugene L., Duraiswami, Chaya, Grygielko, Eugene T., Xu, Xiaoping, Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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Journal Article
Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists
Washburn, David G., Hoang, Tram H., Frazee, James S., Johnson, Latisha, Hammond, Marlys, Manns, Sharada, Madauss, Kevin P., Williams, Shawn P., Duraiswami, Chaya, Tran, Thuy B., Stewart, Eugene L., Grygielko, Eugene T., Glace, Lindsay E., Trizna, Walter, Nagilla, Rakesh, Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
Brooks Carl, Cheung Mui, Eidam Hilary Schenck, Goodman Krista B, Hammond Marlys, Hilfiker Mark A, Hoang Tram H, Patterson Jaclyn R, Stoy Patrick, Ye Guosen and GlaxoSmithKliine LLC Submit United States Patent Application for TRPV4 Antagonists
Published in Global IP News. Pharmaceutical Patent News
(08.05.2014)
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Newsletter
WIPO PUBLISHES PATENT OF GLAXOSMITHKLINE, MUI CHEUNG, HILARY SCHENCK EIDAM, KRISTA B. GOODMAN, MARLYS HAMMOND, MARK A. HILFIKER, TRAM H. HOANG, JACLYN R. PATTERSON, PATRICK STOY, GUOSEN YE AND CARL BROOKS FOR "TRPV4 ANTAGONISTS" (AMERICAN INVENTORS)
Published in US Fed News Service, Including US State News
(30.01.2013)
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Newsletter
Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors
ELBAN, Mark Andrew, DONG, Xiaoyang, HOANG, Tram H, GUANG, Jie, HO, Ming-Hsun, ROMANO, Joseph J, WASHBURN, David Glenn
Year of Publication 14.03.2024
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Year of Publication 14.03.2024
Patent
2,3-dihydroquinazolin compounds as NAV1.8 inhibitors
Jie GUANG, Mark ELBAN, Maben YING, William H. MILLER, Joseph J. ROMANO, David G. WASHBURN, Tram H. HOANG, Ming-Hsun HO, Roderick S. DAVIS, Mythily VIMAL
Year of Publication 14.12.2023
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Year of Publication 14.12.2023
Patent
NITROGEN CONTAINING 2,3-DIHYDROQUINAZOLINONE COMPOUNDS AS NAV1.8 INHIBITORS
ELBAN, Mark Andrew, DONG, Xiaoyang, HOANG, Tram H, GUANG, Jie, HO, Ming-Hsun, ROMANO, Joseph J, WASHBURN, David Glenn
Year of Publication 25.10.2023
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Year of Publication 25.10.2023
Patent
Compuestos 2,3-dihidroquinazolin como inhibidores nav1 .8
HOANG, Tram H, MILLER, William H, ELBAN, Mark, VIMAL, Mythily, WASHBURN, David G, GUANG, Jie, YING, Maben, DAVIS, Roderick S, HO, Ming-Hsun, ROMANO, Joseph J
Year of Publication 21.04.2023
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Year of Publication 21.04.2023
Patent
2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS
ELBAN, Mark, HOANG, Tram H, MILLER, William H, VIMAL, Mythily, WASHBURN, David G, GUANG, Jie, YING, Maben, DAVIS, Roderick S, HO, Ming-Hsun, ROMANO, Joseph J
Year of Publication 06.04.2023
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Year of Publication 06.04.2023
Patent
NITROGEN CONTAINING 2,3-DIHYDROQUINAZOLINONE COMPOUNDS AS NAV1.8 INHIBITORS
ELBAN, MARK ANDREW, ROMANO, JOSEPH J, GUANG, JIE, HOANG, TRAM H, WASHBURN, DAVID GLENN, HO, MING-HSUN, DONG, XIAOYANG
Year of Publication 23.06.2022
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Year of Publication 23.06.2022
Patent
NITROGEN CONTAINING 2,3-DIHYDROQUINAZOLINONE COMPOUNDS AS NAV1.8 INHIBITORS
ELBAN, Mark Andrew, DONG, Xiaoyang, HOANG, Tram H, GUANG, Jie, HO, Ming-Hsun, ROMANO, Joseph J, WASHBURN, David Glenn
Year of Publication 23.06.2022
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Year of Publication 23.06.2022
Patent
2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS
HOANG, Tram H, MILLER, William H, ELBAN, Mark, VIMAL, Mythily, WASHBURN, David G, GUANG, Jie, YING, Maben, DAVIS, Roderick S, HO, Ming-Hsun, ROMANO, Joseph J
Year of Publication 04.05.2022
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Year of Publication 04.05.2022
Patent