Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway
Priest, Christina, Nagari, Rohith T, Bideyan, Lara, Lee, Stephen D, Nguyen, Alexander, Xiao, Xu, Tontonoz, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
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Journal Article
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling
Corsello, Steven M, Nagari, Rohith T, Spangler, Ryan D, Rossen, Jordan, Kocak, Mustafa, Bryan, Jordan G, Humeidi, Ranad, Peck, David, Wu, Xiaoyun, Tang, Andrew A, Wang, Vickie M, Bender, Samantha A, Lemire, Evan, Narayan, Rajiv, Montgomery, Philip, Ben-David, Uri, Garvie, Colin W, Chen, Yejia, Rees, Matthew G, Lyons, Nicholas J, McFarland, James M, Wong, Bang T, Wang, Li, Dumont, Nancy, O'Hearn, Patrick J, Stefan, Eric, Doench, John G, Harrington, Caitlin N, Greulich, Heidi, Meyerson, Matthew, Vazquez, Francisca, Subramanian, Aravind, Roth, Jennifer A, Bittker, Joshua A, Boehm, Jesse S, Mader, Christopher C, Tsherniak, Aviad, Golub, Todd R
Published in Nature cancer (01.02.2020)
Published in Nature cancer (01.02.2020)
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Journal Article
Genetic and Proteomic Analyses of Pupylation in Streptomyces coelicolor
Compton, Corey L, Fernandopulle, Michael S, Nagari, Rohith T, Sello, Jason K
Published in Journal of bacteriology (01.09.2015)
Published in Journal of bacteriology (01.09.2015)
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Journal Article
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis
Xiao, Xu, Kennelly, John Paul, Ferrari, Alessandra, Clifford, Bethan L, Whang, Emily, Gao, Yajing, Qian, Kevin, Sandhu, Jaspreet, Jarrett, Kelsey E, Brearley-Sholto, Madelaine C, Nguyen, Alexander, Nagari, Rohith T, Lee, Min Sub, Zhang, Sicheng, Weston, Thomas A, Young, Stephen G, Bensinger, Steven J, Villanueva, Claudio J, de Aguiar Vallim, Thomas Q, Tontonoz, Peter
Published in Nature metabolism (01.01.2023)
Published in Nature metabolism (01.01.2023)
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Journal Article
Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome
Becker, Andrew P, Biletch, Elijah, Kennelly, John Paul, Julio, Ashley R, Villaneuva, Miranda, Nagari, Rohith T, Turner, Daniel W, Burton, Nikolas R, Fukuta, Tomoyuki, Cui, Liujuan, Xiao, Xu, Hong, Soon-Gook, Mack, Julia J, Tontonoz, Peter, Backus, Keriann M
Published in bioRxiv (24.08.2024)
Published in bioRxiv (24.08.2024)
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Journal Article
Cholesterol binding to VCAM-1 promotes vascular inflammation
Kennelly, John P, Xiao, Xu, Gao, Yajing, Kim, Sumin, Hong, Soon-Gook, Villanueva, Miranda, Ferrari, Alessandra, Vanharanta, Lauri, Nguyen, Alexander, Nagari, Rohith T, Burton, Nikolas R, Tol, Marcus J, Becker, Andrew P, Lee, Min Jae, Ikonen, Elina, Backus, Keriann M, Mack, Julia J, Tontonoz, Peter
Published in bioRxiv (18.09.2024)
Published in bioRxiv (18.09.2024)
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Journal Article
Abstract 3400: Adenosine receptor antagonists exhibit potent and selective off-target killing of FOXA1-high cancers
Corsello, Steven M., Spangler, Ryan D., Humeidi, Ranad, Harrington, Caitlin N., Nagari, Rohith T., Singh, Ritu, Wang, Vickie, Kocak, Mustafa, Rossen, Jordan, Madec, Amael, Dumont, Nancy, Golub, Todd R.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 2948: Novel cell line barcoding method reveals tepoxalin as a selective drug against MDR1-high tumor cells
Corsello, Steven M., Spangler, Ryan D., Nagari, Rohith T., Kocak, Mustafa, Rossen, Jordan, O'Hearn, Patrick, Roth, Jennifer, Gonzalez, Alfredo, Dumont, Nancy, Doench, John, Boehm, Jesse S., Vazquez, Francisca, Tsherniak, Aviad, Golub, Todd R.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Non-oncology drugs are a source of previously unappreciated anti-cancer activity
Corsello, Steven M, Nagari, Rohith T, Spangler, Ryan D, Jordan, Rossen, Kocak, Mustafa, Bryan, Jordan G, Humeidi, Ranad, Peck, David, Wu, Xiaoyun, Tang, Andrew A, Wang, Vickie M, Bender, Samantha A, Lemire, Evan, Narayan, Rajiv, Montgomery, Philip, Ben-David, Uri, Chen, Yejia, Rees, Matthew G, Lyons, Nicholas J, Mcfarland, James M, Wong, Bang T, Wang, Li, Dumont, Nancy, O'hearn, Patrick J, Stefan, Eric, Doench, John G, Greulich, Heidi, Meyerson, Matthew, Vazquez, Francisca, Subramanian, Aravind, Roth, Jennifer A, Bittker, Joshua A, Boehm, Jesse S, Mader, Christopher C, Tsherniak, Aviad, Golub, Todd R
Published in bioRxiv (09.08.2019)
Published in bioRxiv (09.08.2019)
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Paper
Abstract 3588: Discovery of potent and selective CSNK1A1 inhibitors for solid tumor therapy
Corsello, Steven M., Zhang, Huajia, Rupaimoole, Rajesha, Schulze, Volker K., Lemos, Clara, Handing, Kasia B., Orsi, Douglas L., Shekhar, Mrinal, Sack, Ulrike, Christian, Sven, Bone, Wilhelm, Humeidi, Ranad, Colgan, William, Hoyt, Stephanie, Cherniack, Andrew, Schroder, Jens, Kaulfuss, Stefan, Brzezinka, Krzysztof, von Ahsen, Oliver, Mengel, Anne, Hillig, Roman C., Suelzle, Detlev, Mortier, Jeremie, Harrington, Caitlin, Nagari, Rohith, Wierzbinska, Justyna, Chiang, Derek, Beckmann, Georg, Olive, Meagan, Udeshi, Namrata, Apffel, Annie, Carr, Steven, Lienau, Philip, Lechner, Christian, Boemer, Ulf, Caliman, Alisha, McKinney, David, Wagner, Florence, Mumberg, Dominik, Bauser, Marcus, Haegebarth, Andrea, Eis, Knut, Eheim, Ashley, Golub, Todd R.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS
NAGARI, Rohith, SPANGLER, Ryan, GOLUB, Todd, MADEC, Amael, CORSELLO, Steven
Year of Publication 10.08.2022
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Year of Publication 10.08.2022
Patent
ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS
NAGARI, Rohith, SPANGLER, Ryan, GOLUB, Todd, MADEC, Amael, CORSELLO, Steven
Year of Publication 20.01.2022
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Year of Publication 20.01.2022
Patent