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Enhancement of Fibrinolysis by EF6265 [(S)-7-Amino-2-[[[(R)-2-methyl-1-(3-phenylpropanoylamino)propyl]hydroxyphosphinoyl] methyl]heptanoic Acid], a Specific Inhibitor of Plasma Carboxypeptidase B

Enhancement of Fibrinolysis by EF6265 [(S)-7-Amino-2-[[[(R)-2-methyl-1-(3-phenylpropanoylamino)propyl]hydroxyphosphinoyl] methyl]heptanoic Acid], a Specific Inhibitor of Plasma Carboxypeptidase B

by Suzuki, Kokichi, Muto, Yuko, Fushihara, Kenichi, Kanemoto, Ken-ichi, Iida, Hiroyuki, Sato, Eriko, Kikuchi, Chika, Matsushima, Tetsuya, Kato, Emiko, Nomoto, Masahiro, Yoshioka, Shin, Ishii, Hidemi
Published in The Journal of pharmacology and experimental therapeutics (01.05.2004)

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Journal Article

A PROCESS FOR PRODUCING CRYSTALS OF A DIAZABICYLOOCTANE DERIVATIVE AND A STABLE LYOPHILIZED COMPOSITION THEREOF

A PROCESS FOR PRODUCING CRYSTALS OF A DIAZABICYLOOCTANE DERIVATIVE AND A STABLE LYOPHILIZED COMPOSITION THEREOF

by OGAWA, TAKAYA, YOKOYAMA, TAKUYA, ICHIKI, MASATO, FUSHIHARA, KENICHI, FURUYAMA, SHUSUKE
Year of Publication 28.02.2023

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Patent

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

by FUSHIHARA, Kenichi, TSUMURA, Takeshi, MOURI, Shinsuke, ISSHIKI, Satoshi, OKUE, Masayuki, SASAKI, Toshiro
Year of Publication 19.09.2024

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Patent

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

by TSUMURA Takeshi, FUSHIHARA Kenichi, MOURI Shinsuke, OKUE Masayuki, SASAKI Toshiro, ISSHIKI Satoshi
Year of Publication 08.05.2024

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Patent

Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing material thereof

Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing material thereof

by TSUMURA Takeshi, FUSHIHARA Kenichi, MOURI Shinsuke, OKUE Masayuki, SASAKI Toshiro, ISSHIKI Satoshi
Year of Publication 01.02.2024

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Patent

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

by TSUMURA Takeshi, FUSHIHARA Kenichi, MOURI Shinsuke, OKUE Masayuki, SASAKI Toshiro, ISSHIKI Satoshi
Year of Publication 25.01.2024

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Patent

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

by Kenichi FUSHIHARA, Masato ICHIKI, Takuya YOKOYAMA, Shusuke FURUYAMA, Takaya OGAWA
Year of Publication 12.04.2022

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Patent

Production process of crystals of diazabicyclooctane derivative and stable lyophilized preparation

Production process of crystals of diazabicyclooctane derivative and stable lyophilized preparation

by Fushihara, Kenichi, Yokoyama, Takuya, Ogawa, Takaya, Ichiki, Masato, Furuyama, Shusuke
Year of Publication 29.10.2021

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Patent

PRODUCTION PROCESS OF CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

PRODUCTION PROCESS OF CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

by SHUSUKE FURUYAMA, MASATO ICHIKI, TAKAYA OGAWA, TAKUYA YOKOYAMA, KENICHI FUSHIHARA
Year of Publication 27.10.2021

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Patent

Process for producing crystals of a diazabicyclooctane derivative

Process for producing crystals of a diazabicyclooctane derivative

by Fushihara, Kenichi, Yokoyama, Takuya, Ogawa, Takaya, Ichiki, Masato, Furuyama, Shusuke
Year of Publication 14.09.2021

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Patent

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF

by OKUE, MASAYUKI, ISSHIKI, SATOSHI, SASAKI, TOSHIRO, FUSHIHARA, KENICHI, MOURI, SHINSUKE, TSUMURA, TAKESHI
Year of Publication 05.01.2023

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Patent

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

by ICHIKI, Masato, YOKOYAMA, Takuya, FUSHIHARA, Kenichi, FURUYAMA, Shusuke, OGAWA, Takaya
Year of Publication 02.09.2020

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Patent

Method for producing crystals of diazabicyclooctane derivative and stable lyophilized preparation

Method for producing crystals of diazabicyclooctane derivative and stable lyophilized preparation

by Fushihara, Kenichi, Yokoyama, Takuya, Ogawa, Takaya, Ichiki, Masato, Furuyama, Shusuke
Year of Publication 21.05.2020

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Patent

Medium-Membered Ring Ketone Synthesis. Synthesis of Oxa- and Aza-crclooctanone Derivatives

Medium-Membered Ring Ketone Synthesis. Synthesis of Oxa- and Aza-crclooctanone Derivatives

by OHTSUKA, Yasuo, FUSHIHARA, Kenichi, KOBAYASHI, Shogo, KAWAMURA, Ken-ichi, IIMORI, Takamasa, OISHI, Takeshi
Published in Chemical & pharmaceutical bulletin (1992)

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Journal Article

PROCESS FOR PRODUCING CRYSTALS OF A DIAZABICYCLOOCTANE DERIVATIVE

PROCESS FOR PRODUCING CRYSTALS OF A DIAZABICYCLOOCTANE DERIVATIVE

by ICHIKI, Masato, YOKOYAMA, Takuya, FUSHIHARA, Kenichi, FURUYAMA, Shusuke, OGAWA, Takaya
Year of Publication 04.07.2019

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Patent

Lyophilized composition of a diazabicyclooctane compound and process of producing the same

Lyophilized composition of a diazabicyclooctane compound and process of producing the same

by Fushihara, Kenichi, Yokoyama, Takuya, Ogawa, Takaya, Ichiki, Masato, Furuyama, Shusuke
Year of Publication 21.05.2019

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Patent

Processo de produção de cristais de derivado de diazabiciclo-octano e preparação liofilizada estável

Processo de produção de cristais de derivado de diazabiciclo-octano e preparação liofilizada estável

by ICHIKI MASATO, OGAWA TAKAYA, YOKOYAMA TAKUYA, FURUYAMA SHUSUKE, FUSHIHARA KENICHI
Year of Publication 27.02.2024

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Patent

Processo de produção de cristais de derivado de diazabiciclo-octano e preparação liofilizada estável

Processo de produção de cristais de derivado de diazabiciclo-octano e preparação liofilizada estável

by ICHIKI MASATO, OGAWA TAKAYA, YOKOYAMA TAKUYA, FURUYAMA SHUSUKE, FUSHIHARA KENICHI
Year of Publication 30.01.2024

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Patent

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

by ICHIKI, Masato, YOKOYAMA, Takuya, FUSHIHARA, Kenichi, FURUYAMA, Shusuke, OGAWA, Takaya
Year of Publication 02.05.2018

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Patent

PRODUCTION PROCESS OF CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

PRODUCTION PROCESS OF CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION

by FUSHIHARA Kenichi, ICHIKI Masato, OGAWA Takaya, YOKOYAMA Takuya, FURUYAMA Shusuke
Year of Publication 16.11.2017

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Patent

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