Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma
Sakemura, Reona, Hefazi, Mehrdad, Siegler, Elizabeth L., Cox, Michelle J., Larson, Daniel P., Hansen, Michael J., Roman, Claudia Manriquez, Schick, Kendall J, Can, Ismail, Tapper, Erin E., Horvei, Paulina, Adada, Mohamad M., Bezerra, Evandro D., Fonkoua, Lionel Aurelien Kankeu, Ruff, Michael W., Nevala, Wendy K., Walters, Denise K., Parikh, Sameer A., Lin, Yi, Jelinek, Diane F., Kay, Neil E., Bergsagel, P. Leif, Kenderian, Saad S.
Published in Blood (30.06.2022)
Published in Blood (30.06.2022)
Get full text
Journal Article
IL-4 drives exhaustion of CD8+ CART cells
Stewart, Carli M., Siegler, Elizabeth L., Sakemura, R. Leo, Cox, Michelle J., Huynh, Truc, Kimball, Brooke, Mai, Long, Can, Ismail, Manriquez Roman, Claudia, Yun, Kun, Sirpilla, Olivia, Girsch, James H., Ogbodo, Ekene, Mohammed Ismail, Wazim, Gaspar-Maia, Alexandre, Budka, Justin, Kim, Jenny, Scholler, Nathalie, Mattie, Mike, Filosto, Simone, Kenderian, Saad S.
Published in Nature communications (12.09.2024)
Published in Nature communications (12.09.2024)
Get full text
Journal Article
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts
Sterner, Rosalie M., Sakemura, Reona, Cox, Michelle J., Yang, Nan, Khadka, Roman H., Forsman, Cynthia L., Hansen, Michael J., Jin, Fang, Ayasoufi, Katayoun, Hefazi, Mehrdad, Schick, Kendall J., Walters, Denise K., Ahmed, Omar, Chappell, Dale, Sahmoud, Tarek, Durrant, Cameron, Nevala, Wendy K., Patnaik, Mrinal M., Pease, Larry R., Hedin, Karen E., Kay, Neil E., Johnson, Aaron J., Kenderian, Saad S.
Published in Blood (14.02.2019)
Published in Blood (14.02.2019)
Get full text
Journal Article
Using CRISPR/Cas9 to Knock Out GM-CSF in CAR-T Cells
Sterner, Rosalie M, Cox, Michelle J, Sakemura, Reona, Kenderian, Saad S
Published in Journal of visualized experiments (22.07.2019)
Published in Journal of visualized experiments (22.07.2019)
Get full text
Journal Article
Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia
Cox, Michelle J., Lucien, Fabrice, Sakemura, Reona, Boysen, Justin C., Kim, Yohan, Horvei, Paulina, Manriquez Roman, Claudia, Hansen, Michael J., Tapper, Erin E., Siegler, Elizabeth L., Forsman, Cynthia, Crotts, Sydney B., Schick, Kendall J., Hefazi, Mehrdad, Ruff, Michael W., Can, Ismail, Adada, Mohamad, Bezerra, Evandro, Kankeu Fonkoua, Lionel Aurelien, Nevala, Wendy K., Braggio, Esteban, Ding, Wei, Parikh, Sameer A., Kay, Neil E., Kenderian, Saad S.
Published in Molecular therapy (07.04.2021)
Published in Molecular therapy (07.04.2021)
Get full text
Journal Article
GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity
Cox, Michelle J, Manriquez Roman, Claudia, Tapper, Erin E, Siegler, Elizabeth L, Chappell, Dale, Durrant, Cameron, Ahmed, Omar, Sinha, Sutapa, Mwangi, Raphael, Scott, Nancy S, Hefazi, Mehrdad, Schick, Kendall J, Horvei, Paulina, Ruff, Michael W, Can, Ismail, Adada, Mohamad, Bezerra, Evandro, Kankeu Fonkoua, Lionel Aurelien, Parikh, Sameer A, Kay, Neil E, Sakemura, Reona, Kenderian, Saad S
Published in Leukemia (01.06.2022)
Published in Leukemia (01.06.2022)
Get full text
Journal Article
Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity
Sakemura, Reona, Bansal, Aditya, Siegler, Elizabeth L, Hefazi, Mehrdad, Yang, Nan, Khadka, Roman H, Newsom, Alysha N, Hansen, Michael J, Cox, Michelle J, Manriquez Roman, Claudia, Schick, Kendall J, Can, Ismail, Tapper, Erin E, Nevala, Wendy K, Adada, Mohamad M, Bezerra, Evandro D, Kankeu Fonkoua, Lionel Aurelien, Horvei, Paulina, Ruff, Michael W, Parikh, Sameer A, Pandey, Mukesh K, DeGrado, Timothy R, Suksanpaisan, Lukkana, Kay, Neil E, Peng, Kah-Whye, Russell, Stephen J, Kenderian, Saad S
Published in Cancer immunology research (01.09.2021)
Published in Cancer immunology research (01.09.2021)
Get more information
Journal Article
Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
Sakemura, Reona, Cox, Michelle J, Bansal, Aditya, Roman, Claudia Manriquez, Hefazi, Mehrdad, Vernon, Cynthia J, Glynn, Dianna L, Pandey, Mukesh K, DeGrado, Timothy R, Siegler, Elizabeth L, Kenderian, Saad S
Published in Journal of visualized experiments (17.02.2022)
Published in Journal of visualized experiments (17.02.2022)
Get full text
Journal Article
AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells
Sakemura, R Leo, Hefazi, Mehrdad, Cox, Michelle J, Siegler, Elizabeth L, Sinha, Sutapa, Hansen, Michael J, Stewart, Carli M, Feigin, Jennifer M, Manriquez Roman, Claudia, Schick, Kendall J, Can, Ismail, Tapper, Erin E, Horvei, Paulina, Adada, Mohamad M, Bezerra, Evandro D, Kankeu Fonkoua, Lionel Aurelien, Ruff, Michael W, Forsman, Cynthia L, Nevala, Wendy K, Boysen, Justin C, Tschumper, Renee C, Grand, Cory L, Kuchimanchi, Kameswara R, Mouritsen, Lars, Foulks, Jason M, Warner, Steven L, Call, Timothy G, Parikh, Sameer A, Ding, Wei, Kay, Neil E, Kenderian, Saad S
Published in Cancer immunology research (01.09.2023)
Published in Cancer immunology research (01.09.2023)
Get more information
Journal Article
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression
Sirpilla, Olivia, Sakemura, R Leo, Hefazi, Mehrdad, Huynh, Truc N, Can, Ismail, Girsch, James H, Tapper, Erin E, Cox, Michelle J, Schick, Kendall J, Manriquez-Roman, Claudia, Yun, Kun, Stewart, Carli M, Ogbodo, Ekene J, Kimball, Brooke L, Mai, Long K, Gutierrez-Ruiz, Omar L, Rodriguez, Makena L, Gluscevic, Martina, Larson, Daniel P, Abel, Alex M, Wierson, Wesley A, Olivier, Gloria, Siegler, Elizabeth L, Kenderian, Saad S
Published in Nature biomedical engineering (01.04.2024)
Published in Nature biomedical engineering (01.04.2024)
Get more information
Journal Article
Eliminating high-intensity activity during growth reduces mechanical power capacity but not submaximal metabolic cost in a bipedal animal model
Cox, Suzanne Michelle, Salzano, Matthew Q, Piazza, Stephen J, Rubenson, Jonas
Published in Journal of applied physiology (1985) (01.01.2020)
Published in Journal of applied physiology (1985) (01.01.2020)
Get full text
Journal Article
Effect of subcutaneous tissue depth on outcomes of kidney transplantation
Ruiz, Richard, Cox, Thomas, McKenna, Gregory J., Onaca, Nicholas, Testa, Giuliano, Fernandez, Hoylan, Bayer, Johanna, Wall, Anji, Martinez, Eric, Gupta, Amar, DiNubila, J. Michelle, Jennings, Nicole, Wicklund, Kari
Published in Proceedings - Baylor University. Medical Center (18.12.2020)
Published in Proceedings - Baylor University. Medical Center (18.12.2020)
Get full text
Journal Article
Using CRISPR/Cas9 to Knock Out GM-CSF in CAR-T Cells
Sterner, Rosalie M., Cox, Michelle J., Sakemura, Reona, Kenderian, Saad S.
Published in Journal of visualized experiments (22.07.2019)
Published in Journal of visualized experiments (22.07.2019)
Get full text
Journal Article
Emergency Department Visit Rates and Patterns in Canada’s Vancouver Coastal Health Region
McGregor, Margaret J., McGrail, Kimberlyn M., Abu-Laban, Riyad B., Ronald, Lisa A., Baumbusch, Jennifer, Andrusiek, Douglas, Cox, Michelle B.
Published in Canadian journal on aging (01.06.2014)
Published in Canadian journal on aging (01.06.2014)
Get full text
Journal Article
Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models
Sirpilla, Olivia, Sakemura, Reona Leo, Hefazi, Mehrdad, Girsch, James H., Huynh, Truc, Cox, Michelle J., Schick, Kendall J., Manriquez-Roman, Claudia, Can, Ismail, Yun, Kun, Stewart, Carli M., Ogbodo, Ekene J., Siegler, Elizabeth L., Kenderian, Saad S.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
Identification of IL-4 As a Key Regulator of CAR T-Cell Exhaustion Using Functional Genomics and Correlates of the Zuma-1 Clinical Trial
Stewart, Carli M., Cox, Michelle J., Sakemura, Reona Leo, Ogbodo, Ekene J., Can, Ismail, Manriquez-Roman, Claudia, Yun, Kun, Sirpilla, Olivia, Girsch, James H., Huynh, Truc, Siegler, Elizabeth L., Kim, Jenny J, Mattie, Mike, Scholler, Nathalie, Filosto, Simone, Kenderian, Saad S.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article