Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11
zur Stadt, Udo, Rohr, Jan, Seifert, Wenke, Koch, Florian, Grieve, Samantha, Pagel, Julia, Strauß, Julia, Kasper, Brigitte, Nürnberg, Gudrun, Becker, Christian, Maul-Pavicic, Andrea, Beutel, Karin, Janka, Gritta, Griffiths, Gillian, Ehl, Stephan, Hennies, Hans Christian
Published in American journal of human genetics (09.10.2009)
Published in American journal of human genetics (09.10.2009)
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A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Bryceson, Yenan T., Pende, Daniela, Maul-Pavicic, Andrea, Gilmour, Kimberly C., Ufheil, Heike, Vraetz, Thomas, Chiang, Samuel C., Marcenaro, Stefania, Meazza, Raffaella, Bondzio, Ilka, Walshe, Denise, Janka, Gritta, Lehmberg, Kai, Beutel, Karin, zur Stadt, Udo, Binder, Nadine, Arico, Maurizio, Moretta, Lorenzo, Henter, Jan-Inge, Ehl, Stephan
Published in Blood (22.03.2012)
Published in Blood (22.03.2012)
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Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies
Cazzaniga, Giovanni, De Lorenzo, Paola, Alten, Julia, Röttgers, Silja, Hancock, Jeremy, Saha, Vaskar, Castor, Anders, Madsen, Hans O, Gandemer, Virginie, Cavé, Hélène, Leoni, Veronica, Köhler, Rolf, Ferrari, Giulia M, Bleckmann, Kirsten, Pieters, Rob, van der Velden, Vincent, Stary, Jan, Zuna, Jan, Escherich, Gabriele, Stadt, Udo Zur, Aricò, Maurizio, Conter, Valentino, Schrappe, Martin, Valsecchi, Maria Grazia, Biondi, Andrea
Published in Haematologica (Roma) (01.01.2018)
Published in Haematologica (Roma) (01.01.2018)
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Disease‐causing mutations in the XIAP BIR2 domain impair NOD2‐dependent immune signalling
Damgaard, Rune Busk, Fiil, Berthe Katrine, Speckmann, Carsten, Yabal, Monica, Stadt, Udo zur, Bekker‐Jensen, Simon, Jost, Philipp J., Ehl, Stephan, Mailand, Niels, Gyrd‐Hansen, Mads
Published in EMBO molecular medicine (01.08.2013)
Published in EMBO molecular medicine (01.08.2013)
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Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group
Escherich, Gabriele, Zur Stadt, Udo, Borkhardt, Arndt, Dilloo, Dagmar, Faber, Jörg, Feuchtinger, Tobias, Imschweiler, Thomas, Jorch, Norbert, Pekrun, Arnulf, Schmid, Irene, Schramm, Franziska, Spohn, Michael, Zimmermann, Martin, Horstmann, Martin A
Published in Haematologica (Roma) (01.05.2022)
Published in Haematologica (Roma) (01.05.2022)
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Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A
Stadt, Udo Zur, Beutel, Karin, Kolberg, Susanne, Schneppenheim, Reinhard, Kabisch, Hartmut, Janka, Gritta, Hennies, Hans Christian
Published in Human mutation (01.01.2006)
Published in Human mutation (01.01.2006)
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Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants
Süßmuth, Kira, Metze, Dieter, Muresan, Ana-Maria, Lehmberg, Kai, Zur Stadt, Udo, Speckmann, Carsten, Park, Julien Heinrich, Marquardt, Thorsten, Oji, Vinzenz, Goerge, Tobias
Published in Acta dermato-venereologica (01.01.2020)
Published in Acta dermato-venereologica (01.01.2020)
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Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation
Klemann, Christian, MD, Ammann, Sandra, PhD, Heizmann, Miriam, Fuchs, Sebastian, PhD, Bode, Sebastian F., MD, Heeg, Maximilian, MD, Fuchs, Hans, MD, Lehmberg, Kai, MD, zur Stadt, Udo, MD, Roll, Claudia, MD, Vraetz, Thomas, MD, Speckmann, Carsten, MD, Lorenz, Myriam Ricarda, PhD, Schwarz, Klaus, MD, Rohr, Jan, MD, Feske, Stefan, MD, Ehl, Stephan, MD
Published in Journal of allergy and clinical immunology (01.12.2017)
Published in Journal of allergy and clinical immunology (01.12.2017)
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The role of constitutive activation of FMS-related tyrosine kinase-3 and NRas/KRas mutational status in infants with KMT2A -rearranged acute lymphoblastic leukemia
Fedders, Henning, Alsadeq, Ameera, Schmäh, Juliane, Vogiatzi, Fotini, Zimmermann, Martin, Möricke, Anja, Lenk, Lennart, Stadt, Udo Zur, Horstmann, Martin A, Pieters, Rob, Schrappe, Martin, Stanulla, Martin, Cario, Gunnar, Schewe, Denis M
Published in Haematologica (Roma) (01.11.2017)
Published in Haematologica (Roma) (01.11.2017)
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Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases
ROHR, Jan, BEUTEL, Karin, WOESSMANN, Wilhelm, GROLL, Andreas H, STRAHM, Brigitte, PAGEL, Julia, SPECKMANN, Carsten, JANKA, Gritta, GRIFFITHS, Gillian, SCHWARZ, Klaus, ZUR STADT, Udo, EHL, Stephan, MAUL-PAVICIC, Andrea, VRAETZ, Thomas, THIEL, Jens, WARNATZ, Klaus, BONDZIO, Ilka, GROSS-WIELTSCH, Ute, SCHÜNDELN, Michael, SCHÜTZ, Barbara
Published in Haematologica (Roma) (01.12.2010)
Published in Haematologica (Roma) (01.12.2010)
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Late Recurrence of Childhood T-Cell Acute Lymphoblastic Leukemia Frequently Represents a Second Leukemia Rather Than a Relapse: First Evidence for Genetic Predisposition
SZCZEPANSKI, Tomasz, VAN DER VELDEN, Vincent H. J, ZUR STADT, Udo, CAMPANA, Dario, SCHRAUDER, André, SUTTON, Rosemary, VAN WERING, Elisabeth, MEIJERINK, Jules P. P, VAN DONGEN, Jacques J. M, WAANDERS, Esmé, KUIPER, Roland P, VAN VLIERBERGHE, Pieter, GRUHN, Bernd, ECKERT, Cornelia, PANZER-GRÜMAYER, Renate, BASSO, Giuseppe, CAVE, Hélène
Published in Journal of clinical oncology (20.04.2011)
Published in Journal of clinical oncology (20.04.2011)
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Submicroscopic bone marrow involvement in isolated extramedullary relapses in childhood acute lymphoblastic leukemia: a more precise definition of “isolated” and its possible clinical implications, a collaborative study of the Resistant Disease Committee of the International BFM study group
Hagedorn, Nikola, Acquaviva, Cécile, Fronkova, Eva, von Stackelberg, Arend, Barth, Andrea, zur Stadt, Udo, Schrauder, André, Trka, Jan, Gaspar, Nathalie, Seeger, Karl, Henze, Günter, Cavé, Hélène, Eckert, Cornelia
Published in Blood (01.12.2007)
Published in Blood (01.12.2007)
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The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97)
ESCHERICH, Gabriele, TRÖGER, Anja, PIETERS, Rob, DEN BOER, Monique L, HORSTMANN, Martin, JANKA, Gritta E, GÖBEL, Ulrich, GRAUBNER, Ulrike, PEKRUN, Arnulf, JORCH, Norbert, KASPERS, Gjl, ZIMMERMANN, Martin, ZUR STADT, Udo, KAZEMIER, Karin
Published in Haematologica (Roma) (01.06.2011)
Published in Haematologica (Roma) (01.06.2011)
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Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease
Heeg, Maximilian, Ammann, Sandra, Klemann, Christian, Panning, Marcus, Falcone, Valeria, Hengel, Harmut, Lehmberg, Kai, zur Stadt, Udo, Wustrau, Katharina, Janka, Gritta, Ehl, Stephan
Published in Pediatric blood & cancer (01.11.2018)
Published in Pediatric blood & cancer (01.11.2018)
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Variant ALK‐fusion positive anaplastic large cell lymphoma (ALCL): A population‐based paediatric study of the NHL‐BFM study group
Luedersen, Jette, Stadt, Udo zur, Richter, Julia, Oschlies, Ilske, Klapper, Wolfram, Rosenwald, Andreas, Kalinova, Marketa, Simonitsch‐Klupp, Ingrid, Siebert, Reiner, Zimmermann, Martin, Qi, Minyue, Nakel, Jacqueline, Scheinemann, Katrin, Knörr, Fabian, Attarbaschi, Andishe, Kabickova, Edita, Woessmann, Wilhelm, Damm‐Welk, Christine
Published in British journal of haematology (01.05.2024)
Published in British journal of haematology (01.05.2024)
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Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5)
Pagel, Julia, Beutel, Karin, Lehmberg, Kai, Koch, Florian, Maul-Pavicic, Andrea, Rohlfs, Anna-Katharina, Al-Jefri, Abdullah, Beier, Rita, Bomme Ousager, Lilian, Ehlert, Karoline, Gross-Wieltsch, Ute, Jorch, Norbert, Kremens, Bernhard, Pekrun, Arnulf, Sparber-Sauer, Monika, Mejstrikova, Ester, Wawer, Angela, Ehl, Stephan, zur Stadt, Udo, Janka, Gritta
Published in Blood (21.06.2012)
Published in Blood (21.06.2012)
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Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first‐line intensified treatment of pediatric patients with high‐risk acute lymphoblastic leukemia in CoALL08‐09 trial
Mezger, Kerstin, Ebert, Sabine, Muhle, Hannah Elisa, Stadt, Udo zur, Borkhardt, Arndt, Dilloo, Dagmar, Faber, Jörg, Feuchtinger, Tobias, Imschweiler, Thomas, Jorch, Norbert, Pekrun, Arnulf, Schmid, Irene, Schramm, Franziska, Zimmermann, Martin, Horstmann, Martin A, Escherich, Gabriele
Published in Pediatric blood & cancer (01.12.2022)
Published in Pediatric blood & cancer (01.12.2022)
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Syntaxin 11 is required for NK and CD8+ T‐cell cytotoxicity and neutrophil degranulation
D'Orlando, Orietta, Zhao, Fang, Kasper, Brigitte, Orinska, Zane, Müller, Jürgen, Hermans‐Borgmeyer, Irm, Griffiths, Gillian M., Zur Stadt, Udo, Bulfone‐Paus, Silvia
Published in European journal of immunology (01.01.2013)
Published in European journal of immunology (01.01.2013)
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