Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps
Chen, Kaiwen W, Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D, von Pein, Jessica B, Broz, Petr, Sweet, Matthew J, Schroder, Kate
Published in Science immunology (24.08.2018)
Published in Science immunology (24.08.2018)
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Journal Article
Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L., Schroder, Kate
Published in Cell reports (Cambridge) (07.08.2018)
Published in Cell reports (Cambridge) (07.08.2018)
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Journal Article
Modified horseshoe crab peptides target and kill bacteria inside host cells
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira, Lawrence, Nicole
Published in Cellular and molecular life sciences : CMLS (01.01.2022)
Published in Cellular and molecular life sciences : CMLS (01.01.2022)
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Journal Article
Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan, Sweet, Matthew J.
Published in Journal of leukocyte biology (01.02.2021)
Published in Journal of leukocyte biology (01.02.2021)
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Journal Article
Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion
Chen, Kaiwen W, Lawlor, Kate E, von Pein, Jessica B, Boucher, Dave, Gerlic, Motti, Croker, Ben A, Bezbradica, Jelena S, Vince, James E, Schroder, Kate
Published in The Journal of immunology (1950) (15.05.2018)
Published in The Journal of immunology (1950) (15.05.2018)
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Journal Article
Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes
Ross, Connie, Chan, Amy H, von Pein, Jessica B, Maddugoda, Madhavi P, Boucher, Dave, Schroder, Kate
Published in Annual review of immunology (26.04.2022)
Published in Annual review of immunology (26.04.2022)
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An alloy of zinc and innate immunity: Galvanising host defence against infection
von Pein, Jessica B., Stocks, Claudia J., Schembri, Mark A., Kapetanovic, Ronan, Sweet, Matthew J.
Published in Cellular microbiology (01.01.2021)
Published in Cellular microbiology (01.01.2021)
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Journal Article
Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia
Duszyc, Kinga, von Pein, Jessica B., Ramnath, Divya, Currin-Ross, Denni, Verma, Suzie, Lim, Fayth, Sweet, Matthew J., Schroder, Kate, Yap, Alpha S.
Published in Developmental cell (06.11.2023)
Published in Developmental cell (06.11.2023)
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Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P., Sweet, Matthew J.
Published in Cell reports (Cambridge) (25.02.2020)
Published in Cell reports (Cambridge) (25.02.2020)
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Journal Article
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages
Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B, Curson, James E B, Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S, Murthy, Ambika M V, Stocks, Claudia J, Kapetanovic, Ronan, Reid, Robert C, Iyer, Abishek, Ilka, Zoe C, Nauseef, William M, Plan, Manuel, Luo, Lin, Stow, Jennifer L, Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R, Schembri, Mark A, Fairlie, David P, Sweet, Matthew J
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
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Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme
Chan, Amy H, Burgener, Sabrina S, Vezyrgiannis, Kassandra, Wang, Xiaohui, Acklam, Jadie, Von Pein, Jessica B, Pizzuto, Malvina, Labzin, Larisa I, Boucher, Dave, Schroder, Kate
Published in Life science alliance (01.10.2023)
Published in Life science alliance (01.10.2023)
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Journal Article
Modified defence peptides from horseshoe crab target and kill bacteria inside host cells
Amiss, Anna S, Von Pein, Jessica B, Webb, Jessica R, Condon, Nicholas D, Harvey, Peta J, Minh-Duy Phan, Schembri, Mark A, Currie, Bart J, Sweet, Matthew J, Craik, David J, Kapetanovic, Ronan, Henriques, Sonia Troeira, Lawrence, Nicole
Published in bioRxiv (28.06.2021)
Published in bioRxiv (28.06.2021)
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