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Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults
Pillet, Stéphane, Couillard, Julie, Trépanier, Sonia, Poulin, Jean-François, Yassine-Diab, Bader, Guy, Bruno, Ward, Brian J., Landry, Nathalie
Published in PloS one (05.06.2019)
Published in PloS one (05.06.2019)
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A Novel Intramuscular Bivalent Norovirus Virus-Like Particle Vaccine Candidate—Reactogenicity, Safety, and Immunogenicity in a Phase 1 Trial in Healthy Adults
Treanor, John J., Atmar, Robert L., Frey, Sharon E., Gormley, Robert, Chen, Wilbur H., Ferreira, Jennifer, Goodwin, Robert, Borkowski, Astrid, Clemens, Ralf, Mendelman, Paul M.
Published in The Journal of infectious diseases (01.12.2014)
Published in The Journal of infectious diseases (01.12.2014)
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Phase III: Randomized observer-blind trial to evaluate lot-to-lot consistency of a new plant-derived quadrivalent virus like particle influenza vaccine in adults 18–49 years of age
Ward, Brian J., Séguin, Annie, Couillard, Julie, Trépanier, Sonia, Landry, Nathalie
Published in Vaccine (05.03.2021)
Published in Vaccine (05.03.2021)
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ISCOMATRIX™ adjuvant promotes epitope spreading and antibody affinity maturation of influenza A H7N9 virus like particle vaccine that correlate with virus neutralization in humans
Chung, Ka Yan, Coyle, Elizabeth M., Jani, Dewal, King, Lisa R., Bhardwaj, Rukmini, Fries, Louis, Smith, Gale, Glenn, Gregory, Golding, Hana, Khurana, Surender
Published in Vaccine (31.07.2015)
Published in Vaccine (31.07.2015)
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Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines
Ward, Brian J., Landry, Nathalie, Trépanier, Sonia, Mercier, Geneviève, Dargis, Michèle, Couture, Manon, D’Aoust, Marc-André, Vézina, Louis-P.
Published in Vaccine (21.10.2014)
Published in Vaccine (21.10.2014)
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Safety and persistent immunogenicity of a quadrivalent human papillomavirus types 6, 11, 16, 18 L1 virus-like particle vaccine in preadolescents and adolescents: a randomized controlled trial
Reisinger, Keith S, Block, Stan L, Lazcano-Ponce, Eduardo, Samakoses, Rudiwilai, Esser, Mark T, Erick, Joanne, Puchalski, Derek, Giacoletti, Katherine E D, Sings, Heather L, Lukac, Suzanne, Alvarez, Frances B, Barr, Eliav
Published in The Pediatric infectious disease journal (01.03.2007)
Published in The Pediatric infectious disease journal (01.03.2007)
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Adjuvanted Intranasal Norwalk Virus-Like Particle Vaccine Elicits Antibodies and Antibody-Secreting Cells That Express Homing Receptors for Mucosal and Peripheral Lymphoid Tissues
El-Kamary, Samer S., Pasetti, Marcela F., Mendelman, Paul M., Frey, Sharon E., Bernstein, David I., Treanor, John J., Ferreira, Jennifer, Chen, Wilbur H., Sublett, Richard, Richardson, Charles, Bargatze, Robert F., Sztein, Marcelo B., Tacket, Carol O.
Published in The Journal of infectious diseases (01.12.2010)
Published in The Journal of infectious diseases (01.12.2010)
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The Impact of Quadrivalent Human Papillomavirus (HPV; Types 6, 11, 16, and 18) L1 Virus-Like Particle Vaccine on Infection and Disease Due to Oncogenic Nonvaccine HPV Types in Generally HPV-Naive Women Aged 16–26 Years
Brown, Darron R., Kjaer, Susanne K., Sigurdsson, Kristján, Iversen, Ole-Erik, Hernandez-Avila, Mauricio, Wheeler, Cosette M., Perez, Gonzalo, Koutsky, Laura A., Tay, Eng Hseon, Garcia, Patricía, Ault, Kevin A., Garland, Suzanne M., Leodolter, Sepp, Olsson, Sven-Eric, Tang, Grace W. K., Ferris, Daron G., Paavonen, Jorma, Steben, Marc, Bosch, F. Xavier, Dillner, Joakim, Joura, Elmar A., Kurman, Robert J., Majewski, Slawomir, Muñoz, Nubia, Myers, Evan R., Villa, Luisa L., Taddeo, Frank J., Roberts, Christine, Tadesse, Amha, Bryan, Janine, Lupinacci, Lisa C., Giacoletti, Katherine E. D., Sings, Heather L., James, Margaret, Hesley, Teresa M., Barr, Eliav
Published in The Journal of infectious diseases (01.04.2009)
Published in The Journal of infectious diseases (01.04.2009)
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Targeting of phosphorylated tau at threonine 181 by a Qβ virus‐like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques
Maphis, Nicole M., Hulse, Jonathan, Peabody, Julianne, Dadras, Somayeh, Whelpley, Madelin J, Kandath, Manas, Wilson, Colin, Hobson, Sasha, Thompson, Jeff, Poolsup, Suttinee, Beckman, Danielle, Ott, Sean P, Watanabe, Jennifer W., Usachenko, Jodie L., Van Rompay, Koen K, Morrison, John, Selwyn, Reed, Rosenberg, Gary, Knoefel, Janice, Chackerian, Bryce, Bhaskar, Kiran
Published in Alzheimer's & dementia (01.03.2025)
Published in Alzheimer's & dementia (01.03.2025)
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Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers
Low, Jenny G.H., Lee, Lawrence S., Ooi, Eng Eong, Ethirajulu, Kantharaj, Yeo, Pauline, Matter, Alex, Connolly, John E., Skibinski, David A.G., Saudan, Philippe, Bachmann, Martin, Hanson, Brendon J., Lu, Qingshu, Maurer-Stroh, Sebastian, Lim, Sam, Novotny-Diermayr, Veronica
Published in Vaccine (03.09.2014)
Published in Vaccine (03.09.2014)
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High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up
Villa, L L, Costa, R L R, Petta, C A, Andrade, R P, Paavonen, J, Iversen, O-E, Olsson, S-E, Høye, J, Steinwall, M, Riis-Johannessen, G, Andersson-Ellstrom, A, Elfgren, K, Krogh, G von, Lehtinen, M, Malm, C, Tamms, G M, Giacoletti, K, Lupinacci, L, Railkar, R, Taddeo, F J, Bryan, J, Esser, M T, Sings, H L, Saah, A J, Barr, E
Published in British journal of cancer (04.12.2006)
Published in British journal of cancer (04.12.2006)
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The Impact of Quadrivalent Human Papillomavirus (HPV; Types 6, 11, 16, and 18) L1 Virus-Like Particle Vaccine on Infection and Disease Due to Oncogenic Nonvaccine HPV Types in Sexually Active Women Aged 16–26 Years
Wheeler, Cosette M., Kjaer, Susanne K., Sigurdsson, Kristján, Iversen, Ole-Erik, Hernandez-Avila, Mauricio, Perez, Gonzalo, Brown, Darron R., Koutsky, Laura A., Tay, Eng Hseon, García, Patricia, Ault, Kevin A., Garland, Suzanne M., Leodolter, Sepp, Olsson, Sven-Eric, Tang, Grace W. K., Ferris, Daron G., Paavonen, Jorma, Steben, Marc, Bosch, F. Xavier, Dillner, Joakim, Joura, Elmar A., Kurman, Robert J., Majewski, Slawomir, Muñoz, Nubia, Myers, Evan R., Villa, Luisa L., Taddeo, Frank J., Roberts, Christine, Tadesse, Amha, Bryan, Janine, Lupinacci, Lisa C., Giacoletti, Katherine E. D., James, Margaret, Vuocolo, Scott, Hesley, Teresa M., Barr, Eliav
Published in The Journal of infectious diseases (01.04.2009)
Published in The Journal of infectious diseases (01.04.2009)
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Rapid Responses to 2 Virus-Like Particle Norovirus Vaccine Candidate Formulations in Healthy Adults: A Randomized Controlled Trial
Atmar, Robert L., Baehner, Frank, Cramer, Jakob P., Song, Eric, Borkowski, Astrid, Mendelman, Paul M.
Published in The Journal of infectious diseases (15.09.2016)
Published in The Journal of infectious diseases (15.09.2016)
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Influenza virus-like particle vaccines made in Nicotiana benthamiana elicit durable, poly-functional and cross-reactive T cell responses to influenza HA antigens
Landry, Nathalie, Pillet, Stéphane, Favre, David, Poulin, Jean-François, Trépanier, Sonia, Yassine-Diab, Bader, Ward, Brian J.
Published in Clinical immunology (Orlando, Fla.) (01.10.2014)
Published in Clinical immunology (Orlando, Fla.) (01.10.2014)
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Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine in a blinded, randomized, placebo-controlled trial of adults in Mexico
López-Macías, Constantino, Ferat-Osorio, Eduardo, Tenorio-Calvo, Alejandra, Isibasi, Armando, Talavera, Juan, Arteaga-Ruiz, Oscar, Arriaga-Pizano, Lourdes, Hickman, Somia P., Allende, María, Lenhard, Kathy, Pincus, Steven, Connolly, Kevin, Raghunandan, Ramadevi, Smith, Gale, Glenn, Gregory
Published in Vaccine (13.10.2011)
Published in Vaccine (13.10.2011)
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Induction of immune memory following administration of a prophylactic quadrivalent human papillomavirus (HPV) types 6/11/16/18 L1 virus-like particle (VLP) vaccine
Olsson, Sven-Eric, Villa, Luisa L., Costa, Ronaldo L.R., Petta, Carlos A., Andrade, Rosires P., Malm, Christian, Iversen, Ole-Erik, Høye, John, Steinwall, Margareta, Riis-Johannessen, Grete, Andersson-Ellstrom, Agneta, Elfgren, Kristina, von Krogh, Geo, Lehtinen, Matti, Paavonen, Jorma, Tamms, Gretchen M., Giacoletti, Katherine, Lupinacci, Lisa, Esser, Mark T., Vuocolo, Scott C., Saah, Alfred J., Barr, Eliav
Published in Vaccine (2007)
Published in Vaccine (2007)
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Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial
Chang, Lee-Jah, Dowd, Kimberly A, Mendoza, Floreliz H, Saunders, Jamie G, Sitar, Sandra, Plummer, Sarah H, Yamshchikov, Galina, Sarwar, Uzma N, Hu, Zonghui, Enama, Mary E, Bailer, Robert T, Koup, Richard A, Schwartz, Richard M, Akahata, Wataru, Nabel, Gary J, Mascola, John R, Pierson, Theodore C, Graham, Barney S, Ledgerwood, Julie E
Published in The Lancet (British edition) (06.12.2014)
Published in The Lancet (British edition) (06.12.2014)
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A simple and high efficiency purification of His-tagged turnip yellow mosaic virus-like particle (TYMV-VLP) by nickel ion affinity precipitation
Tan, Foo Hou, Ng, Jeck Fei, Mohamed Alitheen, Noorjahan Banu, Muhamad, Azira, Yong, Chean Yeah, Lee, Khai Wooi
Published in Journal of virological methods (01.09.2023)
Published in Journal of virological methods (01.09.2023)
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