The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy
Shimshek, Derya R, Mueller, Matthias, Wiessner, Christoph, Schweizer, Tatjana, van der Putten, P Herman
Published in PloS one (02.04.2010)
Published in PloS one (02.04.2010)
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Journal Article
Gastrin-releasing peptide signaling plays a limited and subtle role in amygdala physiology and aversive memory
Chaperon, Frederique, Fendt, Markus, Kelly, Peter H, Lingenhoehl, Kurt, Mosbacher, Johannes, Olpe, Hans-Rudolf, Schmid, Peter, Sturchler, Christine, McAllister, Kevin H, van der Putten, P Herman, Gee, Christine E
Published in PloS one (11.04.2012)
Published in PloS one (11.04.2012)
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Journal Article
High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain
Herzig, Martin C, Bidinosti, Michael, Schweizer, Tatjana, Hafner, Thomas, Stemmelen, Christine, Weiss, Andreas, Danner, Simone, Vidotto, Nella, Stauffer, Daniela, Barske, Carmen, Mayer, Franziska, Schmid, Peter, Rovelli, Giorgio, van der Putten, P Herman, Shimshek, Derya R
Published in PloS one (15.05.2012)
Published in PloS one (15.05.2012)
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Journal Article
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
HERZIG, Martin C, KOLLY, Carine, SCHNELL, Christian R, MUELLER, Matthias, KINZEL, Bernd, GREVOT, Armelle, BOLOGNANI, Federico, STIRN, Martina, KUHN, Rainer R, KAUPMANN, Klemens, VAN DER PUTTEN, P. Herman, ROVELLI, Giorgio, PERSOHN, Elke, SHIMSHEK, Derya R, THEIL, Diethilde, SCHWEIZER, Tatjana, HAFNER, Thomas, STEMMELEN, Christine, TROXLER, Thomas J, SCHMID, Peter, DANNER, Simone
Published in Human molecular genetics (01.11.2011)
Published in Human molecular genetics (01.11.2011)
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Journal Article
Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice
Young, Douglas, Mayer, Franziska, Vidotto, Nella, Schweizer, Tatjana, Berth, Ramon, Abramowski, Dorothee, Shimshek, Derya R, van der Putten, P Herman, Schmid, Peter
Published in PloS one (23.09.2013)
Published in PloS one (23.09.2013)
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Journal Article
Transneuronal propagation of mutant huntingtin contributes to non–cell autonomous pathology in neurons
Pecho-Vrieseling, Eline, Rieker, Claus, Fuchs, Sascha, Bleckmann, Dorothee, Esposito, Maria Soledad, Botta, Paolo, Goldstein, Chris, Bernhard, Mario, Galimberti, Ivan, Müller, Matthias, Lüthi, Andreas, Arber, Silvia, Bouwmeester, Tewis, van der Putten, Herman, Di Giorgio, Francesco Paolo
Published in Nature neuroscience (01.08.2014)
Published in Nature neuroscience (01.08.2014)
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Journal Article
Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging
Marcellin, David, Abramowski, Dorothee, Young, Douglas, Richter, Jens, Weiss, Andreas, Marcel, Audrey, Maassen, Julia, Kauffmann, Muriel, Bibel, Miriam, Shimshek, Derya R, Faull, Richard L M, Bates, Gillian P, Kuhn, Rainer R, Van der Putten, P Herman, Schmid, Peter, Lotz, Gregor P
Published in PloS one (12.09.2012)
Published in PloS one (12.09.2012)
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Journal Article
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
Mielcarek, Michal, Landles, Christian, Weiss, Andreas, Bradaia, Amyaouch, Seredenina, Tamara, Inuabasi, Linda, Osborne, Georgina F, Wadel, Kristian, Touller, Chrystelle, Butler, Rachel, Robertson, Janette, Franklin, Sophie A, Smith, Donna L, Park, Larry, Marks, Paul A, Wanker, Erich E, Olson, Eric N, Luthi-Carter, Ruth, van der Putten, Herman, Beaumont, Vahri, Bates, Gillian P
Published in PLoS biology (01.11.2013)
Published in PLoS biology (01.11.2013)
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Journal Article
Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior
Gee, Christine E., Peterlik, Daniel, Neuhäuser, Christoph, Bouhelal, Rochdi, Kaupmann, Klemens, Laue, Grit, Uschold-Schmidt, Nicole, Feuerbach, Dominik, Zimmermann, Kaspar, Ofner, Silvio, Cryan, John F., van der Putten, Herman, Fendt, Markus, Vranesic, Ivo, Glatthar, Ralf, Flor, Peter J.
Published in The Journal of biological chemistry (18.04.2014)
Published in The Journal of biological chemistry (18.04.2014)
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Journal Article
Genetic and pharmacological evidence of a role for GABAB receptors in the modulation of anxiety- and antidepressant-like behavior
MOMBEREAU, Cedric, KAUPMANN, Klemens, FROESTL, Wolfgang, SANSIG, Gilles, VAN DER PUTTEN, Herman, CRYAN, John F
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2004)
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2004)
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Journal Article
Endogenous Serine Protease Inhibitor Modulates Epileptic Activity and Hippocampal Long-Term Potentiation
Luthi, Andreas, Putten, Herman van der, Botteri, Florence M, Mansuy, Isabelle M, Meins, Marita, Frey, Uwe, Sansig, Gilles, Portet, Chantal, Schmutz, Markus, Schroder, Markus, Nitsch, Cordula, Laurent, Jean-Paul, Monard, Denis
Published in The Journal of neuroscience (15.06.1997)
Published in The Journal of neuroscience (15.06.1997)
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Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
Gomez-Giro, Gemma, Arias-Fuenzalida, Jonathan, Jarazo, Javier, Zeuschner, Dagmar, Ali, Muhammad, Possemis, Nina, Bolognin, Silvia, Halder, Rashi, Jäger, Christian, Kuper, Willemijn F E, van Hasselt, Peter M, Zaehres, Holm, Del Sol, Antonio, van der Putten, Herman, Schöler, Hans R, Schwamborn, Jens C
Published in Acta neuropathologica communications (30.12.2019)
Published in Acta neuropathologica communications (30.12.2019)
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Activation of the mGlu7 receptor elicits antidepressant-like effects in mice
PALUCHA, Agnieszka, KLAK, Kinga, BRANSKI, Piotr, VAN DER PUTTEN, Herman, FLOR, Peter J, PILC, Andrzej
Published in Psychopharmacologia (01.11.2007)
Published in Psychopharmacologia (01.11.2007)
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Journal Article
Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice
Dobi, Alice, Sartori, Simone B., Busti, Daniela, Van der Putten, Herman, Singewald, Nicolas, Shigemoto, Ryuichi, Ferraguti, Francesco
Published in Neuropharmacology (01.03.2013)
Published in Neuropharmacology (01.03.2013)
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Journal Article
Systemic Deletion of the Myelin-Associated Outgrowth Inhibitor Nogo-A Improves Regenerative and Plastic Responses after Spinal Cord Injury
Simonen, Marjo, Pedersen, Vera, Weinmann, Oliver, Schnell, Lisa, Buss, Armin, Ledermann, Birgit, Christ, Franziska, Sansig, Gilles, van der Putten, Herman, Schwab, Martin E
Published in Neuron (Cambridge, Mass.) (24.04.2003)
Published in Neuron (Cambridge, Mass.) (24.04.2003)
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Journal Article
A Selective Metabotropic Glutamate Receptor 7 Agonist: Activation of Receptor Signaling via an Allosteric Site Modulates Stress Parameters In vivo
Kayo Mitsukawa, Rina Yamamoto, Silvio Ofner, Joachim Nozulak, Oliver Pescott, Snezana Lukic, Natacha Stoehr, Cedric Mombereau, Kuhn, Rainer, Kevin H. Mc Allister, van der Putten, Herman, Cryan, John F., Peter J. Flor, Scolnick, Edward M.
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
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Journal Article
Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition
Cassasus, Guillaume, Barbieri, Samuel, van der Putten, Herman, Humeau, Yann, Ciocchi, Stephane, Shaban, Hamdy, Kaupmann, Klemens, Bettler, Bernhard, Lüthi, Andreas, Herry, Cyril, Shigemoto, Ryuichi
Published in Nature neuroscience (01.08.2006)
Published in Nature neuroscience (01.08.2006)
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Journal Article
Neurochemical and Behavioral Consequences of Widespread Gene Knockdown in the Adult Mouse Brain by Using Nonviral RNA Interference
Thakker, Deepak R., Natt, Francois, Hüsken, Dieter, Maier, Rainer, Müller, Matthias, van der Putten, Herman, Hoyer, Daniel, Cryan, John F., Bloom, Floyd E.
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2004)
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Journal Article
Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Dysregulation of the HPA Axis and Increases Hippocampal BDNF Protein Levels: Implications for Stress-Related Psychiatric Disorders
MITSUKAWA, Kayo, MOMBEREAU, Cedric, LÖTSCHER, Erika, UZUNOV, Doncho P, VAN DER PUTTEN, Herman, FLOR, Peter J, CRYAN, John F
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2006)
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2006)
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Journal Article
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
Herzig, Martin C., Kolly, Carine, Persohn, Elke, Theil, Diethilde, Schweizer, Tatjana, Hafner, Thomas, Stemmelen, Christine, Troxler, Thomas J., Schmid, Peter, Danner, Simone, Schnell, Christian R., Mueller, Matthias, Kinzel, Bernd, Grevot, Armelle, Bolognani, Federico, Stirn, Martina, Kuhn, Rainer R., Kaupmann, Klemens, van der Putten, P. Herman, Rovelli, Giorgio, Shimshek, Derya R.
Published in Human molecular genetics (01.11.2011)
Published in Human molecular genetics (01.11.2011)
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