Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia
Zambetti, Noemi A., Ping, Zhen, Chen, Si, Kenswil, Keane J.G., Mylona, Maria A., Sanders, Mathijs A., Hoogenboezem, Remco M., Bindels, Eric M.J., Adisty, Maria N., Van Strien, Paulina M.H., van der Leije, Cindy S., Westers, Theresia M., Cremers, Eline M.P., Milanese, Chiara, Mastroberardino, Pier G., van Leeuwen, Johannes P.T.M., van der Eerden, Bram C.J., Touw, Ivo P., Kuijpers, Taco W., Kanaar, Roland, van de Loosdrecht, Arjan A., Vogl, Thomas, Raaijmakers, Marc H.G.P.
Published in Cell stem cell (03.11.2016)
Published in Cell stem cell (03.11.2016)
Get full text
Journal Article
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway
Brum, Andrea M., van de Peppel, Jeroen, van der Leije, Cindy S., Schreuders-Koedam, Marijke, Eijken, Marco, van der Eerden, Bram C. J., van Leeuwen, Johannes P. T. M.
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2015)
Get full text
Journal Article
Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia
Polak, Roel, Bierings, Marc B, van der Leije, Cindy S, Sanders, Mathijs A, Roovers, Onno, Marchante, João R M, Boer, Judith M, Cornelissen, Jan J, Pieters, Rob, den Boer, Monique L, Buitenhuis, Miranda
Published in Haematologica (Roma) (01.04.2019)
Published in Haematologica (Roma) (01.04.2019)
Get full text
Journal Article
Using the Connectivity Map to discover compounds influencing human osteoblast differentiation
Brum, Andrea M., van de Peppel, Jeroen, Nguyen, Linh, Aliev, Abidin, Schreuders‐Koedam, Marijke, Gajadien, Tarini, van der Leije, Cindy S., van Kerkwijk, Anke, Eijken, Marco, van Leeuwen, Johannes P.T.M., van der Eerden, B C. J.
Published in Journal of cellular physiology (01.06.2018)
Published in Journal of cellular physiology (01.06.2018)
Get full text
Journal Article
Identification of Chloride Intracellular Channel Protein 3 as a Novel Gene Affecting Human Bone Formation
Brum, Andrea M, van der Leije, Cindy S, Schreuders-Koedam, Marijke, Verhoeven, Jeroen, Janssen, Mark, Dekkers, Dick Hw, Demmers, Jeroen Aa, Eijken, Marco, van de Peppel, Jeroen, van Leeuwen, Johannes Ptm, van der Eerden, Bram Cj
Published in JBMR plus (01.08.2017)
Published in JBMR plus (01.08.2017)
Get full text
Journal Article
Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes
Chen, Si, Zambetti, Noemi A., Ping, Zhen, Kenswil, Keane, Mylona, Maria, Sanders, Mathijs A., Hoogenboezem, Remco, Bindels, Eric, Adisty, Maria, van Strien, Paulina M.H., van der Leije, Cindy, Westers, Theresia M, Cremers, Eline MP, Milanese, Chiara, Mastroberardino, Pier, van Leeuwen, Johannes, Van der Eerden, Bram, Touw, Ivo, Taco, Kuijpers, Kanaar, Roland, van der Loosdrecht, Arjan, Vogl, Thomas, Raaijmakers, Marc H.G.P.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Targeted Therapy for ETV6-RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia
Polak, Roel, Bierings, Marc B., van der Leije, Cindy S., van den Dungen, Rosanna E.S., Sanders, Mathijs A., Roovers, Onno, Cornelissen, Jan J., Marchante, João R.M., Pieters, Rob, den Boer, Monique L., Buitenhuis, Miranda
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article