Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells
van der Pol, Karel H, Koenderink, Jan, van den Heuvel, Jeroen J M W, van den Broek, Petra, Peters, Janny, van Bunningen, Imke D W, Pertijs, Jeanne, Russel, Frans G M, Koldenhof, Jim, Morshuis, Wim J, van Drongelen, Joris, Schirris, Tom J J, van der Meer, Andries, Rongen, Gerard A
Published in PloS one (21.06.2024)
Published in PloS one (21.06.2024)
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Journal Article
Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones
Dankers, Anita C. A, Sweep, Fred C. G. J, Pertijs, Jeanne C. L. M, Verweij, Vivienne, van den Heuvel, Jeroen J. M. W, Koenderink, Jan B, Russel, Frans G. M, Masereeuw, Rosalinde
Published in Cell and tissue research (01.08.2012)
Published in Cell and tissue research (01.08.2012)
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Journal Article
Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates
Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.
Published in Archives of toxicology (01.09.2020)
Published in Archives of toxicology (01.09.2020)
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Journal Article
Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates
van der Velden, Maarten, Bilos, Albert, van den Heuvel, Jeroen J M W, Rijpma, Sanna R, Hurkmans, Evelien G E, Sauerwein, Robert W, Russel, Frans G M, Koenderink, Jan B
Published in Malaria journal (23.10.2017)
Published in Malaria journal (23.10.2017)
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Journal Article
Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule
Smeets, Nori J. L., Litjens, Carlijn H. C., van den Heuvel, Jeroen J. M. W., van Hove, Hedwig, van den Broek, Petra, Russel, Frans G. M., Koenderink, Jan B., de Wildt, Saskia N.
Published in Pharmaceutics (30.09.2020)
Published in Pharmaceutics (30.09.2020)
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Journal Article
Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)
Louisse, Jochem, Dellafiora, Luca, van den Heuvel, Jeroen J. M. W., Rijkers, Deborah, Leenders, Liz, Dorne, Jean-Lou C. M., Punt, Ans, Russel, Frans G. M., Koenderink, Jan B.
Published in Archives of toxicology (01.03.2023)
Published in Archives of toxicology (01.03.2023)
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Journal Article
Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP
Lempers, Vincent J C, van den Heuvel, Jeroen J M W, Russel, Frans G M, Aarnoutse, Rob E, Burger, David M, Brüggemann, Roger J, Koenderink, Jan B
Published in Antimicrobial agents and chemotherapy (01.06.2016)
Published in Antimicrobial agents and chemotherapy (01.06.2016)
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Journal Article
Rifampicin Transport by OATP1B1 Variants
Litjens, Carlijn H C, van den Heuvel, Jeroen J M W, Russel, Frans G M, Aarnoutse, Rob E, Te Brake, Lindsey H M, Koenderink, Jan B
Published in Antimicrobial agents and chemotherapy (21.09.2020)
Published in Antimicrobial agents and chemotherapy (21.09.2020)
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Journal Article
Transport of a fluorescent cAMP analog in teleost proximal tubules
Reichel, Valeska, Masereeuw, Rosalinde, van den Heuvel, Jeroen J. M. W, Miller, David S, Fricker, Gert
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.12.2007)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.12.2007)
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Journal Article
Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol
Te Brake, Lindsey H M, van den Heuvel, Jeroen J M W, Buaben, Aaron O, van Crevel, Reinout, Bilos, Albert, Russel, Frans G, Aarnoutse, Rob E, Koenderink, Jan B
Published in Antimicrobial agents and chemotherapy (01.12.2016)
Published in Antimicrobial agents and chemotherapy (01.12.2016)
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Journal Article
Interaction of Nonsteroidal Anti-Inflammatory Drugs with Multidrug Resistance Protein (MRP) 2/ABCC2- and MRP4/ABCC4-Mediated Methotrexate Transport
El-Sheikh, Azza A K, van den Heuvel, Jeroen J M W, Koenderink, Jan B, Russel, Frans G M
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
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Journal Article
In Silico Identification and in Vitro Validation of Potential Cholestatic Compounds through 3D Ligand-Based Pharmacophore Modeling of BSEP Inhibitors
Ritschel, Tina, Hermans, Susanne M. A, Schreurs, Marieke, van den Heuvel, Jeroen J. M. W, Koenderink, Jan B, Greupink, Rick, Russel, Frans G. M
Published in Chemical research in toxicology (19.05.2014)
Published in Chemical research in toxicology (19.05.2014)
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Journal Article
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
Van Aubel, Rémon A M H, Smeets, Pascal H E, van den Heuvel, Jeroen J M W, Russel, Frans G M
Published in American journal of physiology. Renal physiology (01.02.2005)
Published in American journal of physiology. Renal physiology (01.02.2005)
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Journal Article
Glutathione status and the renal elimination of inorganic mercury in the Mrp2(-/-) mouse
Bridges, Christy C, Joshee, Lucy, van den Heuvel, Jeroen J M W, Russel, Frans G M, Zalups, Rudolfs K
Published in PloS one (05.09.2013)
Published in PloS one (05.09.2013)
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Journal Article
First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine
VANMOLKOT, Kaate R. J, STAM, Anine H, BAJAJ, Nin, TERWINDT, Gisela M, HAAN, Joost, FRANTS, Rune R, FERRARI, Michel D, VAN DEN MAAGDENBERG, Arn M. J. M, RAMAN, Ashok, KOENDERINK, Jan B, DE VRIES, Boukje, VAN DEN BOOJERD, Eelke H, VAN VARK, Judith, HAAN, VAN DEN HEUVEL, Jeroen J. M. W
Published in European journal of human genetics : EJHG (01.08.2007)
Published in European journal of human genetics : EJHG (01.08.2007)
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Journal Article
Cannabinoid Type 1 Receptor Antagonists Modulate Transport Activity of Multidrug Resistance-Associated Proteins MRP1, MRP2, MRP3, and MRP4
WITTGEN, Hanneke G. M, VAN DEN HEUVEL, Jeroen J. M. W, VAN DEN BROEK, Petra H. H, DINTER-HEIDORN, Heike, KOENDERINK, Jan B, RUSSEL, Frans G. M
Published in Drug metabolism and disposition (01.07.2011)
Published in Drug metabolism and disposition (01.07.2011)
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Journal Article
Exploiting Transport Activity of P-Glycoprotein at the Blood–Brain Barrier for the Development of Peripheral Cannabinoid Type 1 Receptor Antagonists
Wittgen, Hanneke G. M, Greupink, Rick, van den Heuvel, Jeroen J. M. W, van den Broek, Petra H. H, Dinter-Heidorn, Heike, Koenderink, Jan B, Russel, Frans G. M
Published in Molecular pharmaceutics (07.05.2012)
Published in Molecular pharmaceutics (07.05.2012)
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Journal Article
In vitro and in silico characterization of the transport of selected perfluoroalkyl carboxylic acids and perfluoroalkyl sulfonic acids by human organic anion transporter 1 (OAT1), OAT2 and OAT3
Louisse, Jochem, Pedroni, Lorenzo, van den Heuvel, Jeroen J.M.W., Rijkers, Deborah, Leenders, Liz, Noorlander, Annelies, Punt, Ans, Russel, Frans G.M., Koenderink, Jan B., Dellafiora, Luca
Published in Toxicology (Amsterdam) (01.12.2024)
Published in Toxicology (Amsterdam) (01.12.2024)
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