The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia
Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Cortés, Roldán, Cunningham, Alan, Pruis, Maurien G., de Boer, Bauke, van den Heuvel, Fiona A. J., Geugien, Marjan, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Published in Nature communications (01.03.2022)
Published in Nature communications (01.03.2022)
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Lipid rafts are essential for peroxisome biogenesis in HepG2 cells
Woudenberg, Jannes, Rembacz, Krzysztof P., Hoekstra, Mark, Pellicoro, Antonella, van den Heuvel, Fiona A. J., Heegsma, Janette, van IJzendoorn, Sven C. D., Holzinger, Andreas, Imanaka, Tsuneo, Moshage, Han, Faber, Klaas Nico
Published in Hepatology (Baltimore, Md.) (01.08.2010)
Published in Hepatology (Baltimore, Md.) (01.08.2010)
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Caveolin‐1 is enriched in the peroxisomal membrane of rat hepatocytes
Woudenberg, Jannes, Rembacz, Krzysztof P., van den Heuvel, Fiona A. J., Woudenberg‐Vrenken, Titia E., Buist‐Homan, Manon, Geuken, Mariska, Hoekstra, Mark, Deelman, Leo E., Enrich, Carlos, Henning, Rob H., Moshage, Han, Faber, Klaas Nico
Published in Hepatology (Baltimore, Md.) (01.05.2010)
Published in Hepatology (Baltimore, Md.) (01.05.2010)
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Unconjugated bile salts shuttle through hepatocyte peroxisomes for taurine conjugation
Rembacz, Krzysztof P., Woudenberg, Jannes, Hoekstra, Mark, Jonkers, Elles Z., van den Heuvel, Fiona A.J., Buist‐Homan, Manon, Woudenberg‐Vrenken, Titia E., Rohacova, Jana, Marin, M. Luisa, Miranda, Miguel A., Moshage, Han, Stellaard, Frans, Faber, Klaas Nico
Published in Hepatology (Baltimore, Md.) (01.12.2010)
Published in Hepatology (Baltimore, Md.) (01.12.2010)
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Human and rat bile acid–CoA:amino acid N‐acyltransferase are liver‐specific peroxisomal enzymes: Implications for intracellular bile salt transport
Pellicoro, Antonella, van den Heuvel, Fiona A. J., Geuken, Mariska, Moshage, Han, Jansen, Peter L. M., Faber, Klaas Nico
Published in Hepatology (Baltimore, Md.) (01.02.2007)
Published in Hepatology (Baltimore, Md.) (01.02.2007)
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Multidrug resistance–associated proteins are crucial for the viability of activated rat hepatic stellate cells
Hannivoort, Rebekka A., Dunning, Sandra, Vander Borght, Sara, Schroyen, Ben, Woudenberg, Jannes, Oakley, Fiona, Buist‐Homan, Manon, van den Heuvel, Fiona A. J., Geuken, Mariska, Geerts, Albert, Roskams, Tania, Faber, Klaas Nico, Moshage, Han
Published in Hepatology (Baltimore, Md.) (01.08.2008)
Published in Hepatology (Baltimore, Md.) (01.08.2008)
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Dietary methionine starvation impairs acute myeloid leukemia progression
Cunningham, Alan, Erdem, Ayşegül, Alshamleh, Islam, Geugien, Marjan, Pruis, Maurien, Pereira-Martins, Diego Antonio, van den Heuvel, Fiona A. J., Wierenga, Albertus T. J., ten Berge, Hilde, Dennebos, Robin, van den Boom, Vincent, Hogeling, Shanna M., Weinhäuser, Isabel, Knops, Ruth, de Blaauw, Pim, Heiner-Fokkema, M. Rebecca, Woolthuis, Carolien, Günther, Ulrich L., Rego, Eduardo M., Martens, Joost H. A., Jansen, Joop H., Schwalbe, Harald, Huls, Gerwin, Schuringa, Jan Jacob
Published in Blood (10.11.2022)
Published in Blood (10.11.2022)
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Proteasome inhibitor MG132 sensitizes HPV‐positive human cervical cancer cells to rhTRAIL‐induced apoptosis
Hougardy, Brigitte M.T., Maduro, John H., van der Zee, Ate G.J., de Groot, Derk Jan A., van den Heuvel, Fiona A.J., de Vries, Elisabeth G.E., de Jong, Steven
Published in International journal of cancer (15.04.2006)
Published in International journal of cancer (15.04.2006)
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Glutathione and antioxidant enzymes serve complementary roles in protecting activated hepatic stellate cells against hydrogen peroxide-induced cell death
Dunning, Sandra, ur Rehman, Atta, Tiebosch, Marjolein H., Hannivoort, Rebekka A., Haijer, Floris W., Woudenberg, Jannes, van den Heuvel, Fiona A.J., Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
Published in Biochimica et biophysica acta (01.12.2013)
Published in Biochimica et biophysica acta (01.12.2013)
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A robust ex vivo model for evaluation of induction of apoptosis by rhTRAIL in combination with proteasome inhibitor MG132 in human premalignant cervical explants
Hougardy, Brigitte M.T., Reesink‐Peters, Nathalie, van den Heuvel, Fiona A.J., ten Hoor, Klaske A., Hollema, Harry, de Vries, Elisabeth G.E., de Jong, Steven, van der Zee, Ate G.J.
Published in International journal of cancer (15.09.2008)
Published in International journal of cancer (15.09.2008)
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Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels
Blokzijl, Hans, Vander Borght, Sara, Bok, Lisette I.H., Libbrecht, Louis, Geuken, Mariska, van den Heuvel, Fiona A.J., Dijkstra, Gerard, Roskams, Tania A.D., Moshage, Han, Jansen, Peter L.M., Faber, Klaas Nico
Published in Inflammatory bowel diseases (01.06.2007)
Published in Inflammatory bowel diseases (01.06.2007)
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Erythroid progenitors from patients with low-risk myelodysplastic syndromes are dependent on the surrounding micro environment for their survival
Folkerts, Hendrik, Hazenberg, Carin L.E, Houwerzijl, Ewout J, van den Heuvel, Fiona A.J, Mulder, André B, van der Want, Johannes J.L, Vellenga, Edo
Published in Experimental hematology (01.03.2015)
Published in Experimental hematology (01.03.2015)
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TAFII170 Interacts with the Concave Surface of TATA-Binding Protein To Inhibit Its DNA Binding Activity
Pereira, Lloyd A., van der Knaap, Jan A., van den Boom, Vincent, van den Heuvel, Fiona A. J., Timmers, H. T. Marc
Published in Molecular and Cellular Biology (01.11.2001)
Published in Molecular and Cellular Biology (01.11.2001)
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Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex
Albert, Thomas K., Hanzawa, Hiroyuki, Legtenberg, Yvonne I.A., de Ruwe, Marjolein J., van den Heuvel, Fiona A.J., Collart, Martine A., Boelens, Rolf, Timmers, H.Th.Marc
Published in The EMBO journal (01.02.2002)
Published in The EMBO journal (01.02.2002)
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Sensitivity to Fas-mediated apoptosis in high-risk HPV-positive human cervical cancer cells: Relationship with Fas, caspase-8, and Bid
Hougardy, Brigitte M.T., van der Zee, Ate G.J., van den Heuvel, Fiona A.J., Timmer, Tineke, de Vries, Elisabeth G.E., de Jong, Steven
Published in Gynecologic oncology (01.05.2005)
Published in Gynecologic oncology (01.05.2005)
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TAF II 170 Interacts with the Concave Surface of TATA-Binding Protein To Inhibit Its DNA Binding Activity
Pereira, Lloyd A., van der Knaap, Jan A., van den Boom, Vincent, van den Heuvel, Fiona A. J., Timmers, H. T. Marc
Published in Molecular and cellular biology (01.11.2001)
Published in Molecular and cellular biology (01.11.2001)
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