Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets
Agbani, Ejaife O, van den Bosch, Marion T.J, Brown, Ed, Williams, Christopher M, Mattheij, Nadine J.A, Cosemans, Judith M.E.M, Collins, Peter W, Heemskerk, Johan W.M, Hers, Ingeborg, Poole, Alastair W
Published in Circulation (New York, N.Y.) (13.10.2015)
Published in Circulation (New York, N.Y.) (13.10.2015)
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Journal Article
Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity
Mastenbroek, Tom G, Feijge, Marion A.H, Kremers, Romy M.W, van den Bosch, Marion T.J, Swieringa, Frauke, De Groef, Lies, Moons, Lieve, Bennett, Cavan, Ghevaert, Cedric, Johnson, Jason L, van der Meijden, Paola E.J, Cosemans, Judith M.E.M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2015)
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Journal Article
Loss of the mitochondrial kinase PINK1 does not alter platelet function
Walsh, Tony G., van den Bosch, Marion T. J., Lewis, Kirsty E., Williams, Christopher M., Poole, Alastair W.
Published in Scientific reports (26.09.2018)
Published in Scientific reports (26.09.2018)
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Journal Article
Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic
van den Bosch, Marion T.J., Yahyanejad, Sanaz, Alemdehy, Mir Farshid, Telford, Bryony J., de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Published in Molecular therapy. Nucleic acids (05.03.2021)
Published in Molecular therapy. Nucleic acids (05.03.2021)
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Journal Article
Absence of platelet phenotype in mice lacking the motor protein myosin Va
Harper, Matthew T, van den Bosch, Marion T J, Hers, Ingeborg, Poole, Alastair W
Published in PloS one (18.01.2013)
Published in PloS one (18.01.2013)
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Journal Article
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology
Telford, Bryony J, Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C, Vos, Rogier M, Stegink, Marieke, van den Bosch, Marion T J, Alemdehy, Mir Farshid, van Pinxteren, Laurens A H, Schaapveld, Roel Q J, Janicot, Michel
Published in Oncotarget (02.03.2021)
Published in Oncotarget (02.03.2021)
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Journal Article
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis
Agbani, Ejaife O, Williams, Christopher M, Li, Yong, van den Bosch, Marion Tj, Moore, Samantha F, Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S, Hers, Ingeborg, Poole, Alastair W
Published in JCI insight (17.05.2018)
Published in JCI insight (17.05.2018)
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Journal Article
INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death
Duurland, Chantal L, Gunst, Thijs de, Boer, Harm C den, Bosch, Marion T J van den, Telford, Bryony J, Vos, Rogier M, Xie, Xiaolei, Zang, Mingfa, Wang, Fang, Shao, Yingying, An, Xiaoyu, Wang, Jingjing, Cai, Jie, Bourré, Ludovic, Pinxteren, Laurens A H van, Schaapveld, Roel Q J, Janicot, Michel, Yahyanejad, Sanaz
Published in Oncotarget (12.07.2024)
Published in Oncotarget (12.07.2024)
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Journal Article
Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin αIIbβ3 Activation and Granule Secretion in Platelets
Moore, Samantha F., van den Bosch, Marion T.J., Hunter, Roger W., Sakamoto, Kei, Poole, Alastair W., Hers, Ingeborg
Published in The Journal of biological chemistry (08.02.2013)
Published in The Journal of biological chemistry (08.02.2013)
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Journal Article
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling
Lam, Jeffrey, van den Bosch, Marion, Wegrzyn, Joanna, Parker, Jeremy, Ibrahim, Rawa, Slowski, Kate, Chang, Linda, Martinez-Høyer, Sergio, Condorelli, Gianluigi, Boldin, Mark, Deng, Yu, Umlandt, Patricia, Fuller, Megan, Karsan, Aly
Published in Nature communications (20.06.2018)
Published in Nature communications (20.06.2018)
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Journal Article
Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function
Corbin, Laura J., White, Stephen J., Taylor, Amy E., Williams, Christopher M., Taylor, Kurt, van den Bosch, Marion T., Teasdale, Jack E., Jones, Matthew, Bond, Mark, Harper, Matthew T., Falk, Louise, Groom, Alix, Hazell, Georgina G.J., Paternoster, Lavinia, Munafò, Marcus R., Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Bojesen, Stig E., Relton, Caroline, Min, Josine L., Davey Smith, George, Mumford, Andrew D., Poole, Alastair W., Timpson, Nicholas J.
Published in Circulation research (04.02.2022)
Published in Circulation research (04.02.2022)
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Journal Article
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis
Agbani, Ejaife O., Williams, Christopher M., Li, Yong, van den Bosch, Marion T.J., Moore, Samantha F., Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S., Hers, Ingeborg, Poole, Alastair W.
Published in JCI insight (17.05.2018)
Published in JCI insight (17.05.2018)
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Journal Article
Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX
Marcolino, Eudmar, Siddiqui, Yusra Hasan, van den Bosch, Marion, Poole, Alastair W., Jayaraman, Padma-Sheela, Gaston, Kevin
Published in Oncogenesis (New York, NY) (04.02.2020)
Published in Oncogenesis (New York, NY) (04.02.2020)
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Journal Article
P422: TARGETING THE WT1MUT‐MIR‐193A TRANSCRIPTIONAL AXIS WITH INT‐1B3, A NOVEL LIPID NANOPARTICLE‐FORMULATED MIR‐193A‐3P MIMIC IN ACUTE MYELOID LEUKEMIA
Yang, Xining, Krowiorz, Kathrin, Buelow, Daelynn, Bhayadia, Raj, Kohlschmidt, Jessica, Nicolet, Deedra, Maetzig, Tobias, Pabst, Caroline, Hui, Jeremy, Shad, Arshia, Gao, Sharon, Stephenson, Maria, Wei Wu, Si, Bosch, Marion, Escano, Leo, Lock, Frances, Panahi, Afsaneh, Macphee, Liam, Maksakova, Irina, Amoah, Amanda, Döhner, Konstanze, Fogelstrand, Linda, Eisfeld, Ann‐Kathrin, Yahyanejad, Sanaz, Janicot, Michel, Klusmann, Jan‐Henning, Baker, Sharyn, Oakes, Christopher, Rouhi, Arefeh, Kuchenbauer, Florian
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis
van den Bosch, Marion T. J., Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Duurland, Chantal L., Biemans, Rianne, Dubois, Ludwig J., van Pinxteren, Laurens A. H., Schaapveld, Roel Q. J., Janicot, Michel
Published in Frontiers in drug discovery (07.07.2023)
Published in Frontiers in drug discovery (07.07.2023)
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Journal Article
Wilms' Tumor 1 Functions As a Tumor Suppressor to Suppress FLT3-STAT Signaling and Epigenetic Remodeling in Acute Myeloid Leukemia (CALGB 8461, 9665 and 20202; Alliance)
Buelow, Daelynn, Yang, Xining, Nicolet, Deedra, Mrózek, Krzysztof, Krowiorz, Kathrin, Bhayadia, Raj, Stromatt, Jack, Denny, Anna, Wiegel, Christoph, Corbett, Colin, Abdelbaky, Salma, Xue, Yonger, Dong, Yizhou, Hui, Jeremy, Shad, Arshia, Gao, Sharon, Wu, Si Wei, van den Bosch, Marion, MacPhee, Liam, Escano, Leo, Blachly, James S., Kolitz, Jonathan E, Blum, William, Baer, Maria R., Klusmann, Jan-Henning, Eisfeld, Ann-Kathrin, Rouhi, Arefeh, Baker, Sharyn D., Kuchenbauer, Florian, Oakes, Christopher C.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer
Kotecki, Nuria, Opdam, Frans, Robbrecht, Debbie, Strijbos, Michiel, Kroon, Karlijn, Janicot, Michel, Yahyanejad, Sanaz, Telford, Bryony, van den Bosch, Marion, Alemdehy, Farshid, de Gunst, Thijs, den Boer, Harm, Vos, Rogier M., van Pinxteren, Laurens, Schaapveld, Roel
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Targeting the WT1mut -M ir-193a Transcriptional Axis with INT-1B3, a Novel Lipid Nanoparticle-Formulated Mir -193a-3p Mimic in Acute Myeloid Leukemia
Yang, Xining, Krowiorz, Kathrin, Bhayadia, Raj, Kohlschmidt, Jessica, Nicolet, Deedra, Maetzig, Tobias, Pabst, Caroline, Hui, Jeremy, Shad, Arshia, Gao, Sharon, Stephenson, Maria, Wu, Si Wei, Bosch, Marion van den, Buelow, Daelynn, Baker, Sharyn, Escano, Leo, Lock, Frances E, Panahi, Afsaneh, MacPhee, Liam, Maksakova, Irina, Amoah, Amanda, Döhner, Konstanze, Fogelstrand, Linda, Eisfeld, Ann-Kathrin, Yahyanejad, Sanaz, Janicot, Michel, Oakes, Christopher C., Klusmann, Jan-Henning, Rouhi, Arefeh, Kuchenbauer, Florian
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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