Search Results - "van de Winkel, Jan G. J." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

IL-8 as Antibody Therapeutic Target in Inflammatory Diseases: Reduction of Clinical Activity in Palmoplantar Pustulosis

IL-8 as Antibody Therapeutic Target in Inflammatory Diseases: Reduction of Clinical Activity in Palmoplantar Pustulosis

by Skov, Lone, Beurskens, Frank J, Zachariae, Claus O. C, Reitamo, Sakari, Teeling, Jessica, Satijn, David, Knudsen, Kim M, Boot, Elmieke P. J, Hudson, Debra, Baadsgaard, Ole, Parren, Paul W. H. I, van de Winkel, Jan G. J
Published in The Journal of immunology (1950) (01.07.2008)

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Journal Article

The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

by Teeling, Jessica L, Mackus, Wendy J. M, Wiegman, Luus J. J. M, van den Brakel, Jeroen H. N, Beers, Stephen A, French, Ruth R, van Meerten, Tom, Ebeling, Saskia, Vink, Tom, Slootstra, Jerry W, Parren, Paul W. H. I, Glennie, Martin J, van de Winkel, Jan G. J
Published in Journal of Immunology (01.07.2006)

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Journal Article

IGA FC RECEPTORS

IGA FC RECEPTORS

by Monteiro, Renato C, van de Winkel, Jan G. J
Published in Annual review of immunology (01.01.2003)

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Journal Article

Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

by de Weers, Michel, Tai, Yu-Tzu, van der Veer, Michael S, Bakker, Joost M, Vink, Tom, Jacobs, Daniëlle C H, Oomen, Lukas A, Peipp, Matthias, Valerius, Thomas, Slootstra, Jerry W, Mutis, Tuna, Bleeker, Wim K, Anderson, Kenneth C, Lokhorst, Henk M, van de Winkel, Jan G J, Parren, Paul W H I
Published in The Journal of immunology (1950) (01.02.2011)

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Effector Mechanisms of Recombinant IgA Antibodies against Epidermal Growth Factor Receptor

Effector Mechanisms of Recombinant IgA Antibodies against Epidermal Growth Factor Receptor

by Dechant, Michael, Beyer, Thomas, Schneider-Merck, Tanja, Weisner, Wencke, Peipp, Matthias, van de Winkel, Jan G. J, Valerius, Thomas
Published in Journal of Immunology (01.09.2007)

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Cytokine-induced immune complex binding to the high-affinity IgG receptor, FcγRI, in the presence of monomeric IgG

Cytokine-induced immune complex binding to the high-affinity IgG receptor, FcγRI, in the presence of monomeric IgG

by van der Poel, Cees E., Karssemeijer, Roos A., Boross, Peter, van der Linden, Joke A., Blokland, Miranda, van de Winkel, Jan G.J., Leusen, Jeanette H.W.
Published in Blood (09.12.2010)

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Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

by Schneider-Merck, Tanja, Lammerts van Bueren, Jeroen J, Berger, Sven, Rossen, Kai, van Berkel, Patrick H.C, Derer, Stefanie, Beyer, Thomas, Lohse, Stefan, Bleeker, Wim K, Peipp, Matthias, Parren, Paul W. H. I, van de Winkel, Jan G. J, Valerius, Thomas, Dechant, Michael
Published in The Journal of immunology (1950) (01.01.2010)

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Dual Mode of Action of a Human Anti-Epidermal Growth Factor Receptor Monoclonal Antibody for Cancer Therapy

Dual Mode of Action of a Human Anti-Epidermal Growth Factor Receptor Monoclonal Antibody for Cancer Therapy

by Bleeker, Wim K, Lammerts van Bueren, Jeroen J, van Ojik, Heidi H, Gerritsen, Arnout F, Pluyter, Marielle, Houtkamp, Mischa, Halk, Ed, Goldstein, Joel, Schuurman, Janine, van Dijk, Marc A, van de Winkel, Jan G. J, Parren, Paul W. H. I
Published in The Journal of immunology (1950) (01.10.2004)

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Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells

Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells

by Beum, Paul V, Peek, Elizabeth M, Lindorfer, Margaret A, Beurskens, Frank J, Engelberts, Patrick J, Parren, Paul W H I, van de Winkel, Jan G J, Taylor, Ronald P
Published in The Journal of immunology (1950) (15.09.2011)

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Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

by van der Neut Kolfschoten, Marijn, Schuurman, Janine, Losen, Mario, Bleeker, Wim K., Martínez-Martínez, Pilar, Vermeulen, Ellen, Bleker, Tamara H. den, Wiegman, Luus, Vink, Tom, Aarden, Lucien A., De Baets, Marc H., van de Winkel, Jan G. J., Aalberse, Rob C., Parren, Paul W. H. I.
Published in Science (American Association for the Advancement of Science) (14.09.2007)

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Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

by Peipp, Matthias, Lammerts van Bueren, Jeroen J., Schneider-Merck, Tanja, Bleeker, Wim W.K., Dechant, Michael, Beyer, Thomas, Repp, Roland, van Berkel, Patrick H.C., Vink, Tom, van de Winkel, Jan G.J., Parren, Paul W.H.I., Valerius, Thomas
Published in Blood (15.09.2008)

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Complement Activation on B Lymphocytes Opsonized with Rituximab or Ofatumumab Produces Substantial Changes in Membrane Structure Preceding Cell Lysis

Complement Activation on B Lymphocytes Opsonized with Rituximab or Ofatumumab Produces Substantial Changes in Membrane Structure Preceding Cell Lysis

by Beum, Paul V, Lindorfer, Margaret A, Beurskens, Frank, Stukenberg, P. Todd, Lokhorst, Henk M, Pawluczkowycz, Andrew W, Parren, Paul W. H. I, van de Winkel, Jan G. J, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.07.2008)

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Recombinant dimeric IgA antibodies against the epidermal growth factor receptor mediate effective tumor cell killing

Recombinant dimeric IgA antibodies against the epidermal growth factor receptor mediate effective tumor cell killing

by Lohse, Stefan, Derer, Stefanie, Beyer, Thomas, Klausz, Katja, Peipp, Matthias, Leusen, Jeanette H W, van de Winkel, Jan G J, Dechant, Michael, Valerius, Thomas
Published in The Journal of immunology (1950) (15.03.2011)

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Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

by Diebolder, Christoph A., Beurskens, Frank J., de Jong, Rob N., Koning, Roman I., Strumane, Kristin, Lindorfer, Margaret A., Voorhorst, Marleen, Ugurlar, Deniz, Rosati, Sara, Heck, Albert J. R., van de Winkel, Jan G. J., Wilson, Ian A., Koster, Abraham J., Taylor, Ronald P., Saphire, Erica Ollmann, Burton, Dennis R., Schuurman, Janine, Gros, Piet, Parren, Paul W. H. I.
Published in Science (American Association for the Advancement of Science) (14.03.2014)

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Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

by Labrijn, Aran F, Meesters, Joyce I, de Goeij, Bart E C G, van den Bremer, Ewald T J, Neijssen, Joost, van Kampen, Muriel D, Strumane, Kristin, Verploegen, Sandra, Kundu, Amitava, Gramer, Michael J, van Berkel, Patrick H C, van de Winkel, Jan G J, Schuurman, Janine, Parren, Paul W H I
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)

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Working Mechanism of Immunoglobulin A1 (IgA1) Protease: Cleavage of IgA1 Antibody to Neisseria meningitidis PorA Requires De Novo Synthesis of IgA1 Protease

Working Mechanism of Immunoglobulin A1 (IgA1) Protease: Cleavage of IgA1 Antibody to Neisseria meningitidis PorA Requires De Novo Synthesis of IgA1 Protease

by Vidarsson, Gestur, Overbeeke, Natasja, Stemerding, Annette M, van den Dobbelsteen, Germie, van Ulsen, Peter, van der Ley, Peter, Kilian, Mogens, van de Winkel, Jan G. J
Published in Infection and Immunity (01.10.2005)

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antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility

antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility

by Lammerts van Bueren, Jeroen J, Bleeker, Wim K, Brännström, Annika, von Euler, Anne, Jansson, Magnus, Peipp, Matthias, Schneider-Merck, Tanja, Valerius, Thomas, van de Winkel, Jan G.J, Parren, Paul W.H.I
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)

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N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG

N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG

by van Berkel, Patrick H. C., Gerritsen, Jolanda, Perdok, Gerrard, Valbjørn, Jesper, Vink, Tom, van de Winkel, Jan G. J., Parren, Paul W. H. I.
Published in Biotechnology progress (01.01.2009)

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Journal Article Conference Proceeding

Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti‐CD20 antibody

Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti‐CD20 antibody

by Bleeker, Wim K., Munk, Martin E., Mackus, Wendy J. M., Van Den Brakel, Jeroen H. N., Pluyter, Marielle, Glennie, Martin J., Van De Winkel, Jan G. J., Parren, Paul W. H. I.
Published in British journal of haematology (01.02.2008)

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Journal Article

Binding of Submaximal C1q Promotes Complement-Dependent Cytotoxicity (CDC) of B Cells Opsonized with Anti-CD20 mAbs Ofatumumab (OFA) or Rituximab (RTX): Considerably Higher Levels of CDC Are Induced by OFA than by RTX

Binding of Submaximal C1q Promotes Complement-Dependent Cytotoxicity (CDC) of B Cells Opsonized with Anti-CD20 mAbs Ofatumumab (OFA) or Rituximab (RTX): Considerably Higher Levels of CDC Are Induced by OFA than by RTX

by Pawluczkowycz, Andrew W, Beurskens, Frank J, Beum, Paul V, Lindorfer, Margaret A, van de Winkel, Jan G. J, Parren, Paul W. H. I, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.07.2009)

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