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Hong, Christy, Schubert, Michael, Tijhuis, Andréa E., Requesens, Marta, Roorda, Maurits, van den Brink, Anouk, Ruiz, Lorena Andrade, Bakker, Petra L., van der Sluis, Tineke, Pieters, Wietske, Chen, Mengting, Wardenaar, René, van der Vegt, Bert, Spierings, Diana C. J., de Bruyn, Marco, van Vugt, Marcel A. T. M., Foijer, Floris
Published in Nature (London) (14.07.2022)
Published in Nature (London) (14.07.2022)
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POLQ to the rescue for double-strand break repair during mitosis
van Vugt, Marcel A. T. M., Tijsterman, Marcel
Published in Nature structural & molecular biology (01.12.2023)
Published in Nature structural & molecular biology (01.12.2023)
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BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Published in Nature communications (09.01.2019)
Published in Nature communications (09.01.2019)
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Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer
Bense, Rico D, Sotiriou, Christos, Piccart-Gebhart, Martine J, Haanen, John B A G, van Vugt, Marcel A T M, de Vries, Elisabeth G E, Schröder, Carolien P, Fehrmann, Rudolf S N
Published in JNCI : Journal of the National Cancer Institute (01.01.2017)
Published in JNCI : Journal of the National Cancer Institute (01.01.2017)
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RIF1 promotes replication fork protection and efficient restart to maintain genome stability
Mukherjee, Chirantani, Tripathi, Vivek, Manolika, Eleni Maria, Heijink, Anne Margriet, Ricci, Giulia, Merzouk, Sarra, de Boer, H. Rudolf, Demmers, Jeroen, van Vugt, Marcel A. T. M., Ray Chaudhuri, Arnab
Published in Nature communications (23.07.2019)
Published in Nature communications (23.07.2019)
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DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization
Reinhardt, H. Christian, Hasskamp, Pia, Schmedding, Ingolf, Morandell, Sandra, van Vugt, Marcel A.T.M., Wang, XiaoZhe, Linding, Rune, Ong, Shao-En, Weaver, David, Carr, Steven A., Yaffe, Michael B.
Published in Molecular cell (08.10.2010)
Published in Molecular cell (08.10.2010)
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Transcriptional effects of copy number alterations in a large set of human cancers
Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Published in Nature communications (05.02.2020)
Published in Nature communications (05.02.2020)
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Gene expression analysis identifies global gene dosage sensitivity in cancer
Fehrmann, Rudolf S N, Karjalainen, Juha M, Krajewska, Małgorzata, Westra, Harm-Jan, Maloney, David, Simeonov, Anton, Pers, Tune H, Hirschhorn, Joel N, Jansen, Ritsert C, Schultes, Erik A, van Haagen, Herman H H B M, de Vries, Elisabeth G E, te Meerman, Gerard J, Wijmenga, Cisca, van Vugt, Marcel A T M, Franke, Lude
Published in Nature genetics (01.02.2015)
Published in Nature genetics (01.02.2015)
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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
Zimmerli, Dario, Brambillasca, Chiara S., Talens, Francien, Bhin, Jinhyuk, Linstra, Renske, Romanens, Lou, Bhattacharya, Arkajyoti, Joosten, Stacey E. P., Da Silva, Ana Moises, Padrao, Nuno, Wellenstein, Max D., Kersten, Kelly, de Boo, Mart, Roorda, Maurits, Henneman, Linda, de Bruijn, Roebi, Annunziato, Stefano, van der Burg, Eline, Drenth, Anne Paulien, Lutz, Catrin, Endres, Theresa, van de Ven, Marieke, Eilers, Martin, Wessels, Lodewyk, de Visser, Karin E., Zwart, Wilbert, Fehrmann, Rudolf S. N., van Vugt, Marcel A. T. M., Jonkers, Jos
Published in Nature communications (02.11.2022)
Published in Nature communications (02.11.2022)
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Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51
Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni Maria, de Kanter, Jurrian K., Kok, Yannick P., Everts, Marieke, de Boer, H. Rudolf, Audrey, Anastasia, Bakker, Femke J., Wierenga, Elles, Tijsterman, Marcel, Guryev, Victor, Spierings, Diana C. J., Knipscheer, Puck, van Boxtel, Ruben, Ray Chaudhuri, Arnab, Lansdorp, Peter M., van Vugt, Marcel A. T. M.
Published in Nature communications (07.11.2022)
Published in Nature communications (07.11.2022)
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Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells
Schoonen, Pepijn M., Talens, Francien, Stok, Colin, Gogola, Ewa, Heijink, Anne Margriet, Bouwman, Peter, Foijer, Floris, Tarsounas, Madalena, Blatter, Sohvi, Jonkers, Jos, Rottenberg, Sven, van Vugt, Marcel A. T. M.
Published in Nature communications (17.07.2017)
Published in Nature communications (17.07.2017)
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Improving gene function predictions using independent transcriptional components
Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Published in Nature communications (05.03.2021)
Published in Nature communications (05.03.2021)
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TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells
van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Published in Oncogene (01.02.2019)
Published in Oncogene (01.02.2019)
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Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability
Hengeveld, Rutger C.C., de Boer, H. Rudolf, Schoonen, Pepijn M., de Vries, Elisabeth G.E., Lens, Susanne M.A., van Vugt, Marcel A.T.M.
Published in Developmental cell (24.08.2015)
Published in Developmental cell (24.08.2015)
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