Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
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Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages
Hamers, Anouk A J, van Dam, Laura, Teixeira Duarte, José M, Vos, Mariska, Marinković, Goran, van Tiel, Claudia M, Meijer, Sybren L, van Stalborch, Anne-Marieke, Huveneers, Stephan, Te Velde, Anje A, de Jonge, Wouter J, de Vries, Carlie J M
Published in PloS one (04.08.2015)
Published in PloS one (04.08.2015)
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Discovery of Small Molecule CD40–TRAF6 Inhibitors
Zarzycka, Barbara, Seijkens, Tom, Nabuurs, Sander B, Ritschel, Tina, Grommes, Jochen, Soehnlein, Oliver, Schrijver, Roy, van Tiel, Claudia M, Hackeng, Tilman M, Weber, Christian, Giehler, Fabian, Kieser, Arnd, Lutgens, Esther, Vriend, Gert, Nicolaes, Gerry A. F
Published in Journal of chemical information and modeling (23.02.2015)
Published in Journal of chemical information and modeling (23.02.2015)
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Adipocytes control hematopoiesis and inflammation through CD40 signaling
Reiche, Myrthe E, Poels, Kikkie, Bosmans, Laura A, Vos, Winnie G, Van Tiel, Claudia M, Gijbels, Marion J J, Aarts, Suzanne A B M, Den Toom, Myrthe, Beckers, Linda, Weber, Christian, Atzler, Dorothee, Rensen, Patrick C N, Kooijman, Sander, Lutgens, Esther
Published in Haematologica (Roma) (01.07.2023)
Published in Haematologica (Roma) (01.07.2023)
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The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells
Kurakula, Kondababu, Vos, Mariska, Otermin Rubio, Iker, Marinković, Goran, Buettner, Reinhard, Heukamp, Lukas C, Stap, Jan, de Waard, Vivian, van Tiel, Claudia M, de Vries, Carlie J M
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits
Ruiter, Matthijs S, van Tiel, Claudia M, Doornbos, Albert, Marinković, Goran, Strang, Aart C, Attevelt, Nico J M, de Waard, Vivian, de Winter, Robbert J, Steendam, Rob, de Vries, Carlie J M
Published in PloS one (21.09.2015)
Published in PloS one (21.09.2015)
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T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation
Vos, Winnie G, van Os, Bram W, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy P A A, van Tiel, Claudia M, Mohapatra, Bhopal C, Band, Hamid, Nitz, Katrin, Weber, Christian, Atzler, Dorothee, de Winther, Menno P J, Bosmans, Laura A, Lutgens, Esther, Seijkens, Tom T P
Published in Frontiers in immunology (04.03.2024)
Published in Frontiers in immunology (04.03.2024)
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Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis
Aarts, Suzanne ABM, Seijkens, Tom TP, Kusters, Pascal JH, van Tiel, Claudia M, Reiche, Myrthe E, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy PAA, de Winther, Menno PJ, Kooij, Gijs, Lutgens, Esther
Published in The Journal of pathology (01.04.2019)
Published in The Journal of pathology (01.04.2019)
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Nuclear Receptors Nur77, Nurr1, and NOR-1 Expressed in Atherosclerotic Lesion Macrophages Reduce Lipid Loading and Inflammatory Responses
Bonta, Peter I, van Tiel, Claudia M, Vos, Mariska, Pols, Thijs W.H, van Thienen, Johannes V, Ferreira, Valérie, Arkenbout, E Karin, Seppen, Jurgen, Spek, C Arnold, van der Poll, Tom, Pannekoek, Hans, de Vries, Carlie J.M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
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LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis
Kurakula, Kondababu, Sommer, Daniela, Sokolovic, Milka, Moerland, Perry D., Scheij, Saskia, van Loenen, Pieter B., Koenis, Duco S., Zelcer, Noam, van Tiel, Claudia M., de Vries, Carlie J. M.
Published in Molecular and cellular biology (01.01.2015)
Published in Molecular and cellular biology (01.01.2015)
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Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis
van Os, Bram W, Kusters, Pascal J H, den Toom, Myrthe, Beckers, Linda, van Tiel, Claudia M, Vos, Winnie G, de Jong, Elize, Kieser, Arnd, van Roomen, Cindy, Binder, Christoph J, Reiche, Myrthe E, de Winther, Menno P, Bosmans, Laura A, Lutgens, Esther
Published in Frontiers in cardiovascular medicine (05.05.2023)
Published in Frontiers in cardiovascular medicine (05.05.2023)
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Prolactin does not affect human platelet aggregation or secretion
Reuwer, Anne Q, Nieuwland, Rienk, Fernandez, Isabelle, Goffin, Vincent, van Tiel, Claudia M, Schaap, Marianne C L, Berckmans, René J, Kastelein, John J P, Twickler, Marcel Th B
Published in Thrombosis and haemostasis (01.06.2009)
Published in Thrombosis and haemostasis (01.06.2009)
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Limited Role of Nuclear Receptor Nur77 in Escherichia coli-Induced Peritonitis
Hamers, Anouk A J, Uleman, Sven, van Tiel, Claudia M, Kruijswijk, Daniëlle, van Stalborch, Anne-Marieke, Huveneers, Stephan, de Vries, Carlie J M, van 't Veer, Cornelis
Published in Infection and Immunity (01.01.2014)
Published in Infection and Immunity (01.01.2014)
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NR4A nuclear receptors are orphans but not lonesome
Kurakula, Kondababu, Koenis, Duco S., van Tiel, Claudia M., de Vries, Carlie J.M.
Published in Biochimica et biophysica acta (01.11.2014)
Published in Biochimica et biophysica acta (01.11.2014)
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Book Review
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis
Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Published in Journal of the American College of Cardiology (06.02.2018)
Published in Journal of the American College of Cardiology (06.02.2018)
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Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state
Bosmans, Laura A, van Tiel, Claudia M, Aarts, Suzanne A B M, Willemsen, Lisa, Baardman, Jeroen, van Os, Bram W, Toom, Myrthe den, Beckers, Linda, Ahern, David J, Levels, Johannes H M, Jongejan, Aldo, Moerland, Perry D, Verberk, Sanne G S, den Bossche, Jan van, de Winther, Menno M P J, Weber, Christian, Atzler, Dorothee, Monaco, Claudia, Gerdes, Norbert, Shami, Annelie, Lutgens, Esther
Published in Cardiovascular research (22.05.2023)
Published in Cardiovascular research (22.05.2023)
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Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
PIRES, Nuno M. M, POIS, Thijs W. H, DE VRIES, Carlie J. M, DE VRIES, Margreet R, VAN TIEL, Claudia M, BONTA, Peter I, VOS, Mariska, KARIN ARKENBOUT, E, PANNEKOEK, Hans, WOUTER JUKEMA, J, QUAX, Paul H. A
Published in Circulation (New York, N.Y.) (30.01.2007)
Published in Circulation (New York, N.Y.) (30.01.2007)
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CD40L modulates CD4+ T‐cell activation through receptor for activated C kinase 1
van Os, Bram W., Vos, Winnie G., Bosmans, Laura A., van Tiel, Claudia M., Toom, Myrthe den, Beckers, Linda, Admiraal, Merel, Hoeksema, Marten A., de Winther, Menno P., Lutgens, Esther
Published in European journal of immunology (01.12.2023)
Published in European journal of immunology (01.12.2023)
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Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity
Kane, Jamie, Jansen, Matthijs, Hendrix, Sebastian, Bosmans, Laura A., Beckers, Linda, Tiel, Claudia van, Gijbels, Marion, Zelcer, Noam, Vries, Carlie J. de, von Hundelshausen, Philipp, Vervloet, Marc, Eringa, Ed, Horrevoets, Anton J., Royen, Niels van, Lutgens, Esther
Published in Thrombosis and haemostasis (01.06.2022)
Published in Thrombosis and haemostasis (01.06.2022)
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