Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune‐related adverse events of immune checkpoint inhibitors
Lin, Lishi, Houwink, Aletta P. I., van Dieren, Jolanda M., Wolthuis, Esther K., van Thienen, Johannes V., van der Heijden, Michiel S., Haanen, John B. A. G., Beijnen, Jos H., Huitema, Alwin D. R.
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Published in Cancer medicine (Malden, MA) (01.06.2024)
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Severe Adverse Reaction to Vemurafenib in a Pregnant Woman with Metastatic Melanoma
de Haan, Jorine, van Thienen, Johannes V., Casaer, Michael, Hannivoort, Rebekka A., Van Calsteren, Kristel, van Tuyl, Minke, van Gerwen, Mathilde M., Debeer, Anne, Amant, Frédéric, Painter, Rebecca C.
Published in Case reports in oncology (15.02.2018)
Published in Case reports in oncology (15.02.2018)
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Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management
Geukes Foppen, Marnix H, Rozeman, Elisa A, van Wilpe, Sandra, Postma, Cindy, Snaebjornsson, Petur, van Thienen, Johannes V, van Leerdam, Monique E, van den Heuvel, Michel, Blank, Christian U, van Dieren, Jolanda, Haanen, John B A G
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The PRO-RCC study: a long-term PROspective Renal Cell Carcinoma cohort in the Netherlands, providing an infrastructure for 'Trial within Cohorts' study designs
Yildirim, Hilin, Widdershoven, Christiaan V, Aarts, Maureen Jb, Bex, Axel, Bloemendal, Haiko J, Bochove-Overgaauw, Deirdre M, Hamberg, Paul, Herbschleb, Karin H, van der Hulle, Tom, Lagerveld, Brunolf W, van Oijen, Martijn Gh, Oosting, Sjoukje F, van Thienen, Johannes V, van der Veldt, Astrid Am, Westgeest, Hans M, Zeijdner, Evelijn E, Aben, Katja Kh, van den Hurk, Corina, Zondervan, Patricia J, Bins, Adriaan D
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Published in BMC cancer (11.07.2023)
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Nuclear Receptors Nur77, Nurr1, and NOR-1 Expressed in Atherosclerotic Lesion Macrophages Reduce Lipid Loading and Inflammatory Responses
Bonta, Peter I, van Tiel, Claudia M, Vos, Mariska, Pols, Thijs W.H, van Thienen, Johannes V, Ferreira, Valérie, Arkenbout, E Karin, Seppen, Jurgen, Spek, C Arnold, van der Poll, Tom, Pannekoek, Hans, de Vries, Carlie J.M
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Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
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Primary cilia sensitize endothelial cells for fluid shear stress
Hierck, Beerend P., Van der Heiden, Kim, Alkemade, Fanneke E., Van de Pas, Simone, Van Thienen, Johannes V., Groenendijk, Bianca C.W., Bax, Wilhelmina H., Van der Laarse, Arnoud, DeRuiter, Marco C., Horrevoets, Anton J.G., Poelmann, Robert E.
Published in Developmental dynamics (01.03.2008)
Published in Developmental dynamics (01.03.2008)
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Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2
Tuomisto, Tiina T., Lumivuori, Henri, Kansanen, Emilia, Häkkinen, Sanna-Kaisa, Turunen, Mikko P., van Thienen, Johannes V., Horrevoets, Anton J., Levonen, Anna-Liisa, Ylä-Herttuala, Seppo
Published in Cardiovascular research (01.04.2008)
Published in Cardiovascular research (01.04.2008)
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Endothelial KLF2 Links Local Arterial Shear Stress Levels to the Expression of Vascular Tone-Regulating Genes
Dekker, Rob J., van Thienen, Johannes V., Rohlena, Jakub, de Jager, Saskia C., Elderkamp, Yvonne W., Seppen, Jurgen, de Vries, Carlie J.M., Biessen, Erik A.L., van Berkel, Theo J.C., Pannekoek, Hans, Horrevoets, Anton J.G.
Published in The American journal of pathology (01.08.2005)
Published in The American journal of pathology (01.08.2005)
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Indications and Outcomes for Deferred Cytoreductive Nephrectomy Following Immune Checkpoint Inhibitor Combination Therapy: Can Systemic Therapy be Withdrawn in Patients with No Evidence of Disease?
Fransen van de Putte, Elisabeth E., van den Brink, Luna, Mansour, Mohamed A., van der Mijn, Johannes C., Wilgenhof, Sofie, van Thienen, Johannes V., Haanen, John B.A.G., Boleti, Ekaterini, Powles, Thomas, Zondervan, Patricia J., Graafland, Niels M., Bex, Axel
Published in European urology open science (Online) (01.09.2023)
Published in European urology open science (Online) (01.09.2023)
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Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2
Fledderus, Joost O., van Thienen, Johannes V., Boon, Reinier A., Dekker, Rob J., Rohlena, Jakub, Volger, Oscar L., Bijnens, Ann-Pascale J.J., Daemen, Mat J.A.P., Kuiper, Johan, van Berkel, Theo J.C., Pannekoek, Hans, Horrevoets, Anton J.G.
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Published in Blood (15.05.2007)
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Hypofractionated radiotherapy combined with targeted therapy or immunotherapy: Dutch survey on current practice, knowledge and challenges
van Aken, Evert S.M., van der Linden, Yvette M., van Thienen, Johannes V., de Langen, Adrianus J., Marijnen, Corrie A.M., de Jong, Monique C.
Published in Clinical and translational radiation oncology (01.03.2022)
Published in Clinical and translational radiation oncology (01.03.2022)
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P-Selectin Glycoprotein Ligand-1 Is Expressed on Endothelial Cells and Mediates Monocyte Adhesion to Activated Endothelium
Martins, Paula da Costa, García-Vallejo, Juan-Jesús, van Thienen, Johannes V, Fernandez-Borja, Mar, van Gils, Janine M, Beckers, Cora, Horrevoets, Anton J, Hordijk, Peter L, Zwaginga, Jaap-Jan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2007)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2007)
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Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma
Blank, Christian U., Rozeman, Elisa A., Fanchi, Lorenzo F., Sikorska, Karolina, van de Wiel, Bart, Kvistborg, Pia, Krijgsman, Oscar, van den Braber, Marlous, Philips, Daisy, Broeks, Annegien, van Thienen, Johannes V., Mallo, Henk A., Adriaansz, Sandra, ter Meulen, Sylvia, Pronk, Loes M., Grijpink-Ongering, Lindsay G., Bruining, Annemarie, Gittelman, Rachel M., Warren, Sarah, van Tinteren, Harm, Peeper, Daniel S., Haanen, John B. A. G., van Akkooi, Alexander C. J., Schumacher, Ton N.
Published in Nature medicine (01.11.2018)
Published in Nature medicine (01.11.2018)
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Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma
Chesney, Jason A, Ribas, Antoni, Long, Georgina V, Kirkwood, John M, Dummer, Reinhard, Puzanov, Igor, Hoeller, Christoph, Gajewski, Thomas F, Gutzmer, Ralf, Rutkowski, Piotr, Demidov, Lev, Arenberger, Petr, Shin, Sang Joon, Ferrucci, Pier Francesco, Haydon, Andrew, Hyngstrom, John, van Thienen, Johannes V, Haferkamp, Sebastian, Guilera, Josep Malvehy, Rapoport, Bernardo Leon, VanderWalde, Ari, Diede, Scott J, Anderson, James R, Treichel, Sheryl, Chan, Edward L, Bhatta, Sumita, Gansert, Jennifer, Hodi, Frank Stephen, Gogas, Helen
Published in Journal of clinical oncology (20.01.2023)
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Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial
Rozeman, Elisa A, Menzies, Alexander M, van Akkooi, Alexander C J, Adhikari, Chandra, Bierman, Carolien, van de Wiel, Bart A, Scolyer, Richard A, Krijgsman, Oscar, Sikorska, Karolina, Eriksson, Hanna, Broeks, Annegien, van Thienen, Johannes V, Guminski, Alexander D, Acosta, Alex Torres, ter Meulen, Sylvia, Koenen, Anne Miek, Bosch, Linda J W, Shannon, Kerwin, Pronk, Loes M, Gonzalez, Maria, Ch'ng, Sydney, Grijpink-Ongering, Lindsay G, Stretch, Jonathan, Heijmink, Stijn, van Tinteren, Harm, Haanen, John B A G, Nieweg, Omgo E, Klop, Willem M C, Zuur, Charlotte L, Saw, Robyn P M, van Houdt, Winan J, Peeper, Daniel S, Spillane, Andrew J, Hansson, Johan, Schumacher, Ton N, Long, Georgina V, Blank, Christian U
Published in The lancet oncology (01.07.2019)
Published in The lancet oncology (01.07.2019)
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Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial
Bex, Axel, Mulders, Peter, Jewett, Michael, Wagstaff, John, van Thienen, Johannes V, Blank, Christian U, van Velthoven, Roland, Del Pilar Laguna, Maria, Wood, Lori, van Melick, Harm H E, Aarts, Maureen J, Lattouf, J B, Powles, Thomas, de Jong Md PhD, Igle Jan, Rottey, Sylvie, Tombal, Bertrand, Marreaud, Sandrine, Collette, Sandra, Collette, Laurence, Haanen, John
Published in JAMA oncology (01.02.2019)
Published in JAMA oncology (01.02.2019)
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Avelumab treatment for patients with metastatic Merkel cell carcinoma can be safely stopped after 1 year and a PET/CT–confirmed complete response
Zijlker, Lisanne P., Levy, Sonja, Wolters, Wendy, Thienen, Johannes V., Akkooi, Alexander C. J., Tesselaar, Margot E. T.
Published in Cancer (01.02.2024)
Published in Cancer (01.02.2024)
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Neoadjuvant Cytoreductive Treatment with BRAF/MEK Inhibition of prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single Arm, Open-label Phase II Trial
Blankenstein, Stéphanie A, Rohaan, Maartje W, Klop, W Martin C, van der Hiel, Bernies, van de Wiel, Bart A, Lahaye, Max J, Adriaansz, Sandra, Sikorska, Karolina, van Tinteren, Harm, Sari, Aysegül, Grijpink-Ongering, Lindsay G, van Houdt, Winan J, Wouters, Michel W J M, Blank, Christian U, Wilgenhof, Sofie, van Thienen, Johannes V, van Akkooi, Alexander C J, Haanen, John B A G
Published in Annals of surgery (01.08.2021)
Published in Annals of surgery (01.08.2021)
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A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma
Embaby, Alaa, Huijberts, Sanne C F A, Wang, Liqin, Leite de Oliveira, Rodrigo, Rosing, Hilde, Nuijen, Bastiaan, Sanders, Joyce, Hofland, Ingrid, van Steenis, Charlaine, Kluin, Roelof J C, Lieftink, Cor, Smith, Christopher G, Blank, Christian U, van Thienen, Johannes V, Haanen, John B A G, Steeghs, Neeltje, Opdam, Frans L, Beijnen, Jos H, Huitema, Alwin D R, Bernards, Rene, Schellens, Jan H M, Wilgenhof, Sofie
Published in Clinical cancer research (01.08.2024)
Published in Clinical cancer research (01.08.2024)
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Cytoreductive nephrectomy and exposure to sunitinib – a post hoc analysis of the Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Cancer (SURTIME) trial
Abu‐Ghanem, Yasmin, Thienen, Johannes V., Blank, Christian, Aarts, Maureen J. B., Jewett, Michael, Jong, Igle Jan, Lattouf, Jean‐Baptiste, Melick, Harm H. E., Wood, Lori, Mulders, Peter, Rottey, Sylvie, Wagstaff, John, Zondervan, Patricia, Powles, Tom, Neven, Anouk, Collette, Laurence, Tombal, Bertrand, Haanen, John, Bex, Axel
Published in BJU international (01.07.2022)
Published in BJU international (01.07.2022)
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