The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10
Ates, Louis S, van der Woude, Aniek D, Bestebroer, Jovanka, van Stempvoort, Gunny, Musters, René J P, Garcia-Vallejo, Juan J, Picavet, Daisy I, Weerd, Robert van de, Maletta, Massimiliano, Kuijl, Coenraad P, van der Wel, Nicole N, Bitter, Wilbert
Published in PLoS pathogens (01.06.2016)
Published in PLoS pathogens (01.06.2016)
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Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo
Romano, Maria, van de Weerd, Robert, Brouwer, Femke C.C., Roviello, Giovanni N., Lacroix, Ruben, Sparrius, Marion, van den Brink-van Stempvoort, Gunny, Maaskant, Janneke J., van der Sar, Astrid M., Appelmelk, Ben J., Geurtsen, Jeroen J., Berisio, Rita
Published in Structure (London) (06.05.2014)
Published in Structure (London) (06.05.2014)
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Mycobacteria employ two different mechanisms to cross the blood–brain barrier
Leeuwen, Lisanne M., Boot, Maikel, Kuijl, Coen, Picavet, Daisy I., Stempvoort, Gunny, Pol, Susanne M.A., Vries, Helga E., Wel, Nicole N., Kuip, Martijn, Furth, A. Marceline, Sar, Astrid M., Bitter, Wilbert
Published in Cellular microbiology (01.09.2018)
Published in Cellular microbiology (01.09.2018)
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Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts
Weerdenburg, Eveline M, Abdallah, Abdallah M, Rangkuti, Farania, Abd El Ghany, Moataz, Otto, Thomas D, Adroub, Sabir A, Molenaar, Douwe, Ummels, Roy, Ter Veen, Kars, van Stempvoort, Gunny, van der Sar, Astrid M, Ali, Shahjahan, Langridge, Gemma C, Thomson, Nicholas R, Pain, Arnab, Bitter, Wilbert
Published in Infection and immunity (01.05.2015)
Published in Infection and immunity (01.05.2015)
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An anti-tuberculosis compound screen using a zebrafish infection model identifies an aspartyl-tRNA synthetase inhibitor
Habjan, Eva, Ho, Vien Q T, Gallant, James, van Stempvoort, Gunny, Jim, Kin Ki, Kuijl, Coen, Geerke, Daan P, Bitter, Wilbert, Speer, Alexander
Published in Disease models & mechanisms (01.12.2021)
Published in Disease models & mechanisms (01.12.2021)
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EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF
Phan, Trang H, van Leeuwen, Lisanne M, Kuijl, Coen, Ummels, Roy, van Stempvoort, Gunny, Rubio-Canalejas, Alba, Piersma, Sander R, Jiménez, Connie R, van der Sar, Astrid M, Houben, Edith N G, Bitter, Wilbert
Published in PLoS pathogens (01.08.2018)
Published in PLoS pathogens (01.08.2018)
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Low Density Lipoprotein Receptor-related Protein and Factor IXa Share Structural Requirements for Binding to the A3 Domain of Coagulation Factor VIII
Bovenschen, Niels, Boertjes, Ria C, van Stempvoort, Gunny, Voorberg, Jan, Lenting, Peter J, Meijer, Alexander B, Mertens, Koen
Published in The Journal of biological chemistry (14.03.2003)
Published in The Journal of biological chemistry (14.03.2003)
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Journal Article
The Connecting Segment between Both Epidermal Growth Factor-like Domains in Blood Coagulation Factor IX Contributes to Stimulation by Factor VIIIa and Its Isolated A2 Domain
Celie, Patrick H.N., van Stempvoort, Gunny, Fribourg, Caroline, Schurgers, Leon J., Lenting, Peter J., Mertens, Koen
Published in The Journal of biological chemistry (07.06.2002)
Published in The Journal of biological chemistry (07.06.2002)
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Journal Article
Analysis of SecA2‐dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector
Woude, Aniek D., Stoop, Esther J. M., Stiess, Michael, Wang, Sen, Ummels, Roy, Stempvoort, Gunny, Piersma, Sander R., Cascioferro, Alessandro, Jiménez, Connie R., Houben, Edith N. G., Luirink, Joen, Pieters, Jean, Sar, Astrid M., Bitter, Wilbert
Published in Cellular microbiology (01.02.2014)
Published in Cellular microbiology (01.02.2014)
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Journal Article
Substitution of Arg527 and Arg531 in factor VIII associated with mild haemophilia A: characterization in terms of subunit interaction and cofactor function
Celie, Patrick H. N., Van Stempvoort, Gunny, Jorieux, Sylvie, Mazurier, Claudine, Van Mourik, Jan A., Mertens, Koen
Published in British journal of haematology (01.09.1999)
Published in British journal of haematology (01.09.1999)
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Enhanced Thrombin Sensitivity of a Factor VIII-Heparin Cofactor II Hybrid
Voorberg, J, van Stempvoort, G, Bos, J M, Mertens, K, van Mourik, J A, Donath, M J
Published in The Journal of biological chemistry (30.08.1996)
Published in The Journal of biological chemistry (30.08.1996)
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Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity
Stoop, Esther J. M., Mishra, Arun K., Driessen, Nicole N., Stempvoort, Gunny, Bouchier, Pascale, Verboom, Theo, Leeuwen, Lisanne M., Sparrius, Marion, Raadsen, Susanne A., Zon, Maaike, Wel, Nicole N., Besra, Gurdyal S., Geurtsen, Jeroen, Bitter, Wilbert, Appelmelk, Ben J., Sar, Astrid M.
Published in Cellular microbiology (01.12.2013)
Published in Cellular microbiology (01.12.2013)
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Journal Article
Analysis of SecA2-dependent substrates in M ycobacterium marinum identifies protein kinase G (PknG) as a virulence effector: Mycobacterial SecA2 substrates
van der Woude, Aniek D., Stoop, Esther J. M., Stiess, Michael, Wang, Sen, Ummels, Roy, van Stempvoort, Gunny, Piersma, Sander R., Cascioferro, Alessandro, Jiménez, Connie R., Houben, Edith N. G., Luirink, Joen, Pieters, Jean, van der Sar, Astrid M., Bitter, Wilbert
Published in Cellular microbiology (01.02.2014)
Published in Cellular microbiology (01.02.2014)
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Journal Article
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity: Mannosyltransferase affects granuloma initiation
Stoop, Esther J. M., Mishra, Arun K., Driessen, Nicole N., van Stempvoort, Gunny, Bouchier, Pascale, Verboom, Theo, van Leeuwen, Lisanne M., Sparrius, Marion, Raadsen, Susanne A., van Zon, Maaike, van der Wel, Nicole N., Besra, Gurdyal S., Geurtsen, Jeroen, Bitter, Wilbert, Appelmelk, Ben J., van der Sar, Astrid M.
Published in Cellular microbiology (01.12.2013)
Published in Cellular microbiology (01.12.2013)
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Journal Article
Substitution of Arg 527 and Arg 531 in factor VIII associated with mild haemophilia A: characterization in terms of subunit interaction and cofactor function
Celie, Patrick H. N., Van Stempvoort, Gunny, Jorieux, Sylvie, Mazurier, Claudine, Van Mourik, Jan A., Mertens, Koen
Published in British journal of haematology (01.09.1999)
Published in British journal of haematology (01.09.1999)
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