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Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model
Toonen, Lodewijk J A, Overzier, Maurice, Evers, Melvin M, Leon, Leticia G, van der Zeeuw, Sander A J, Mei, Hailiang, Kielbasa, Szymon M, Goeman, Jelle J, Hettne, Kristina M, Magnusson, Olafur Th, Poirel, Marion, Seyer, Alexandre, 't Hoen, Peter A C, van Roon-Mom, Willeke M C
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Calcium-Enhanced Medium-Based Delivery of Splice Modulating Antisense Oligonucleotides in 2D and 3D hiPSC-Derived Neuronal Models
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Therapeutic Strategies for Spinocerebellar Ataxia Type 1
Kerkhof, Laurie M C, van de Warrenburg, Bart P C, van Roon-Mom, Willeke M C, Buijsen, Ronald A M
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Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients
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Peripheral mitochondrial function correlates with clinical severity in idiopathic Parkinson's disease
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Published in Movement disorders (01.08.2019)
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Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension
Curtis, Maurice A, Kam, Monica, Nannmark, Ulf, Anderson, Michelle F, Axell, Mathilda Zetterstrom, Wikkelso, Carsten, Holtås, Stig, van Roon-Mom, Willeke M.C, Björk-Eriksson, Thomas, Nordborg, Claes, Frisén, Jonas, Dragunow, Michael, Faull, Richard L.M, Eriksson, Peter S
Published in Science (American Association for the Advancement of Science) (02.03.2007)
Published in Science (American Association for the Advancement of Science) (02.03.2007)
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Post‐mortem 7T MR imaging and neuropathology in middle stage juvenile‐onset Huntington disease: A case report
Bakels, Hannah S., Duinen, Sjoerd G., Bresser, Jeroen, Roon‐Mom, Willeke M. C., Weerd, Louise, Bot, Susanne T.
Published in Neuropathology and applied neurobiology (01.02.2023)
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Machine learning in Huntington's disease: exploring the Enroll-HD dataset for prognosis and driving capability prediction
Ouwerkerk, Jasper, Feleus, Stephanie, van der Zwaan, Kasper F, Li, Yunlei, Roos, Marco, van Roon-Mom, Willeke M C, de Bot, Susanne T, Wolstencroft, Katherine J, Mina, Eleni
Published in Orphanet journal of rare diseases (27.07.2023)
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Mapping the glial transcriptome in Huntington's disease using snRNAseq: selective disruption of glial signatures across brain regions
Bøstrand, Sunniva M K, Seeker, Luise A, Bestard-Cuche, Nadine, Kazakou, Nina-Lydia, Jäkel, Sarah, Kenkhuis, Boyd, Henderson, Neil C, de Bot, Susanne T, van Roon-Mom, Willeke M C, Priller, Josef, Williams, Anna
Published in Acta neuropathologica communications (21.10.2024)
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Exploring the transcriptome of ciliated cells using in silico dissection of human tissues
Ivliev, Alexander E, 't Hoen, Peter A C, van Roon-Mom, Willeke M C, Peters, Dorien J M, Sergeeva, Marina G
Published in PloS one (25.04.2012)
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TGFβ pathway deregulation and abnormal phospho‐SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis‐Dutch type
Grand Moursel, Laure, Munting, Leon P., van der Graaf, Linda M., van Duinen, Sjoerd G., Goumans, Marie‐Jose T. H., Ueberham, Uwe, Natté, Remco, van Buchem, Mark A., van Roon‐Mom, Willeke M. C., van der Weerd, Louise
Published in Brain pathology (Zurich, Switzerland) (01.07.2018)
Published in Brain pathology (Zurich, Switzerland) (01.07.2018)
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Potential disease-modifying therapies for Huntington's disease: lessons learned and future opportunities
Tabrizi, Sarah J, Estevez-Fraga, Carlos, van Roon-Mom, Willeke M C, Flower, Michael D, Scahill, Rachael I, Wild, Edward J, Muñoz-Sanjuan, Ignacio, Sampaio, Cristina, Rosser, Anne E, Leavitt, Blair R
Published in Lancet neurology (01.07.2022)
Published in Lancet neurology (01.07.2022)
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Increased Cell Proliferation and Neurogenesis in the Adult Human Huntington's Disease Brain
Curtis, Maurice A., Penney, Ellen B., Pearson, Andree G., Willeke M. C. van Roon-Mom, Butterworth, Niqi J., Dragunow, Michael, Connor, Bronwen, Richard L. M. Faull
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
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In silico discovery and experimental validation of new protein-protein interactions
van Haagen, Herman H.H.B.M, t Hoen, Peter A.C, de Morrée, Antoine, van Roon-Mom, Willeke M.C, Peters, Dorien J.M, Roos, Marco, Mons, Barend, van Ommen, Gert-Jan, Schuemie, Martijn J
Published in Proteomics (Weinheim) (01.03.2011)
Published in Proteomics (Weinheim) (01.03.2011)
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Statistical method for modeling sequencing data from different technologies in longitudinal studies with application to Huntington disease
Fuady, Angga M., van Roon‐Mom, Willeke M. C., Kiełbasa, Szymon M., Uh, Hae‐Won, Houwing‐Duistermaat, Jeanine J.
Published in Biometrical journal (01.04.2021)
Published in Biometrical journal (01.04.2021)
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Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates
Schut, Menno H, Patassini, Stefano, Kim, Eric H, Bullock, Jocelyn, Waldvogel, Henry J, Faull, Richard L M, Pepers, Barry A, den Dunnen, Johan T, van Ommen, Gert-Jan B, van Roon-Mom, Willeke M C
Published in PloS one (01.06.2017)
Published in PloS one (01.06.2017)
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Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brain
Zalachoras, Ioannis, Grootaers, Gwendolynn, van Weert, Lisa T C M, Aubert, Yves, de Kreij, Suzanne R, Datson, Nicole A, van Roon-Mom, Willeke M C, Aartsma-Rus, Annemieke, Meijer, Onno C
Published in BMC neuroscience (07.01.2013)
Published in BMC neuroscience (07.01.2013)
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Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA
Mastrokolias, Anastasios, den Dunnen, Johan T, van Ommen, Gertjan B, 't Hoen, Peter A C, van Roon-Mom, Willeke M C
Published in BMC genomics (18.01.2012)
Published in BMC genomics (18.01.2012)
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Juvenile‐Onset Huntington Disease Pathophysiology and Neurodevelopment: A Review
Bakels, Hannah S., Roos, Raymund A.C., Roon‐Mom, Willeke M.C., Bot, Susanne T.
Published in Movement disorders (01.01.2022)
Published in Movement disorders (01.01.2022)
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