The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy
Kuiper, Esther J, Van Nieuwenhoven, Frans A, de Smet, Marc D, van Meurs, Jan C, Tanck, Michael W, Oliver, Noelynn, Klaassen, Ingeborg, Van Noorden, Cornelis J F, Goldschmeding, Roel, Schlingemann, Reinier O
Published in PloS one (16.07.2008)
Published in PloS one (16.07.2008)
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Culturing of Cardiac Fibroblasts in Engineered Heart Matrix Reduces Myofibroblast Differentiation but Maintains Their Response to Cyclic Stretch and Transforming Growth Factor β1
Ploeg, Meike C, Munts, Chantal, Seddiqi, Tayeba, ten Brink, Tim J. L, Breemhaar, Jonathan, Moroni, Lorenzo, Prinzen, Frits. W, van Nieuwenhoven, Frans. A
Published in Bioengineering (Basel) (01.10.2022)
Published in Bioengineering (Basel) (01.10.2022)
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Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion
Blythe, Nicola M., Muraki, Katsuhiko, Ludlow, Melanie J., Stylianidis, Vasili, Gilbert, Hamish T.J., Evans, Elizabeth L., Cuthbertson, Kevin, Foster, Richard, Swift, Joe, Li, Jing, Drinkhill, Mark J., van Nieuwenhoven, Frans A., Porter, Karen E., Beech, David J., Turner, Neil A.
Published in The Journal of biological chemistry (15.11.2019)
Published in The Journal of biological chemistry (15.11.2019)
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Journal Article
MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload–Induced Heart Failure
Verjans, Robin, Peters, Tim, Beaumont, Francisco Javier, van Leeuwen, Rick, van Herwaarden, Tessa, Verhesen, Wouter, Munts, Chantal, Bijnen, Mitchell, Henkens, Michiel, Diez, Javier, de Windt, Leon J, van Nieuwenhoven, Frans A, van Bilsen, Marc, Goumans, Marie José, Heymans, Stephane, González, Arantxa, Schroen, Blanche
Published in Hypertension (Dallas, Tex. 1979) (01.02.2018)
Published in Hypertension (Dallas, Tex. 1979) (01.02.2018)
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Left atrial remodeling in mitral regurgitation: A combined experimental-computational study
Bouwmeester, Sjoerd, van Loon, Tim, Ploeg, Meike, Mast, Thomas P, Verzaal, Nienke J, van Middendorp, Lars B, Strik, Marc, van Nieuwenhoven, Frans A, Dekker, Lukas R, Prinzen, Frits W, Lumens, Joost, Houthuizen, Patrick
Published in PloS one (15.07.2022)
Published in PloS one (15.07.2022)
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Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR–v-ATPase axis
Wang, Shujin, Schianchi, Francesco, Neumann, Dietbert, Wong, Li-Yen, Sun, Aomin, van Nieuwenhoven, Frans A., Zeegers, Maurice P., Strzelecka, Agnieszka, Col, Umare, Glatz, Jan F.C., Nabben, Miranda, Luiken, Joost J.F.P.
Published in Molecular metabolism (Germany) (01.11.2021)
Published in Molecular metabolism (Germany) (01.11.2021)
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The Complex Relation between Atrial Cardiomyopathy and Thrombogenesis
D’Alessandro, Elisa, Winters, Joris, van Nieuwenhoven, Frans A, Schotten, Ulrich, Verheule, Sander
Published in Cells (Basel, Switzerland) (22.09.2022)
Published in Cells (Basel, Switzerland) (22.09.2022)
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Journal Article
A Lumped Two-Compartment Model for Simulation of Ventricular Pump and Tissue Mechanics in Ischemic Heart Disease
Koopsen, Tijmen, Van Osta, Nick, Van Loon, Tim, Van Nieuwenhoven, Frans A, Prinzen, Frits W, Van Klarenbosch, Bas R, Kirkels, Feddo P, Teske, Arco J, Vernooy, Kevin, Delhaas, Tammo, Lumens, Joost
Published in Frontiers in physiology (11.05.2022)
Published in Frontiers in physiology (11.05.2022)
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Journal Article
CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy
NGUYEN, Tri Q, ROESTENBERG, Peggy, BRANDAN, Enrique, LYONS, Karen M, GOLDSCHMEDING, Roel, VAN NIEUWENHOVEN, Frans A, BOVENSCHEN, Niels, ZEKE LI, XU, Leon, OLIVER, Noelynn, ATEN, Jan, JOLES, Jaap A, VIAL, Cecilia
Published in Journal of the American Society of Nephrology (01.11.2008)
Published in Journal of the American Society of Nephrology (01.11.2008)
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Journal Article
Piezo1 Mechanosensitive Ion Channel Mediates Stretch-Induced Nppb Expression in Adult Rat Cardiac Fibroblasts
Ploeg, Meike C., Munts, Chantal, Prinzen, Frits W., Turner, Neil A., van Bilsen, Marc, van Nieuwenhoven, Frans A.
Published in Cells (Basel, Switzerland) (09.07.2021)
Published in Cells (Basel, Switzerland) (09.07.2021)
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Journal Article
Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice
van Bilsen, Marc, Daniels, Anneleen, Brouwers, Olaf, Janssen, Ben J A, Derks, Wouter J A, Brouns, Agnieszka E, Munts, Chantal, Schalkwijk, Casper G, van der Vusse, Ger J, van Nieuwenhoven, Frans A
Published in PloS one (09.01.2014)
Published in PloS one (09.01.2014)
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Journal Article
Plasma Connective Tissue Growth Factor Is an Independent Predictor of End-Stage Renal Disease and Mortality in Type 1 Diabetic Nephropathy
NGUYEN, Tri Q, TARNOW, Lise, JORSAL, Anders, OLIVER, Noelynn, ROESTENBERG, Peggy, ITO, Yasuhiko, PARVING, Hans-Henrik, ROSSING, Peter, VAN NIEUWENHOVEN, Frans A, GOLDSCHMEDING, Roel
Published in Diabetes care (01.06.2008)
Published in Diabetes care (01.06.2008)
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Journal Article
Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats
Daniels, Anneleen, Linz, Dominik, van Bilsen, Marc, Rütten, Hartmut, Sadowski, Thorsten, Ruf, Sven, Juretschke, Hans-Paul, Neumann-Haefelin, Claudia, Munts, Chantal, van der Vusse, Ger J., van Nieuwenhoven, Frans A.
Published in European journal of heart failure (01.02.2012)
Published in European journal of heart failure (01.02.2012)
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Journal Article
Heat Shock Proteins and Cardiovascular Pathophysiology
Snoeckx, Luc H. E. H, Cornelussen, Richard N, Van Nieuwenhoven, Frans A, Reneman, Robert S, Van der Vusse, Ger J
Published in Physiological reviews (01.10.2001)
Published in Physiological reviews (01.10.2001)
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Journal Article
Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1
D'Alessandro, Elisa, Scaf, Billy, Munts, Chantal, van Hunnik, Arne, Trevelyan, Christopher J, Verheule, Sander, Spronk, Henri M H, Turner, Neil A, Ten Cate, Hugo, Schotten, Ulrich, van Nieuwenhoven, Frans A
Published in Cells (Basel, Switzerland) (30.10.2021)
Published in Cells (Basel, Switzerland) (30.10.2021)
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Journal Article
Urinary Connective Tissue Growth Factor Excretion Correlates With Clinical Markers of Renal Disease in a Large Population of Type 1 Diabetic Patients With Diabetic Nephropathy
Nguyen, Tri Q, Tarnow, Lise, Andersen, Steen, Hovind, Peter, Parving, Hans-Henrik, Goldschmeding, Roel, van Nieuwenhoven, Frans A
Published in Diabetes care (2006)
Published in Diabetes care (2006)
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Journal Article
Stretch-induced hypertrophy of isolated adult rabbit cardiomyocytes
Blaauw, Erik, van Nieuwenhoven, Frans A, Willemsen, Peter, Delhaas, Tammo, Prinzen, Frits W, Snoeckx, Luc H, van Bilsen, Marc, van der Vusse, Ger J
Published in American journal of physiology. Heart and circulatory physiology (01.09.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2010)
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Journal Article
Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice
Roestenberg, Peggy, van Nieuwenhoven, Frans A, Joles, Jaap A, Trischberger, Claudia, Martens, Paula P, Oliver, Noelynn, Aten, Jan, Höppener, Jo W, Goldschmeding, Roel
Published in American journal of physiology. Renal physiology (01.06.2006)
Published in American journal of physiology. Renal physiology (01.06.2006)
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Journal Article
CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress
Hall-Glenn, Faith, Aivazi, Armen, Akopyan, Lusi, Ong, Jessica R., Baxter, Ruth R., Benya, Paul D., Goldschmeding, Roel, van Nieuwenhoven, Frans A., Hunziker, Ernst B., Lyons, Karen M.
Published in Journal of cell communication and signaling (01.08.2013)
Published in Journal of cell communication and signaling (01.08.2013)
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