Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin
Ramirez-Moral, Ivan, Schuurman, Alex R., van Linge, Christine C.A., Butler, Joe M., Yu, Xiao, de Haan, Karen, van Leeuwen, Sarah, de Vos, Alex F., de Jong, Menno D., Vieira Braga, Felipe A., van der Poll, Tom
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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Journal Article
Platelets are Hyperactivated but Show Reduced Glycoprotein VI Reactivity in COVID-19 Patients
Léopold, Valentine, Pereverzeva, Liza, Schuurman, Alex R., Reijnders, Tom D. Y., Saris, Anno, de Brabander, Justin, van Linge, Christine C. A., Douma, Renée A., Chouchane, Osoul, Nieuwland, Rienk, Wiersinga, W. Joost, van 't Veer, Cornelis, van der Poll, Tom
Published in Thrombosis and haemostasis (01.09.2021)
Published in Thrombosis and haemostasis (01.09.2021)
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The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus
Saris, Anno, Qin, Wanhai, van Linge, Christine C. A., Reijnders, Tom D. Y., Florquin, Sandrine, Burnet, Michael, Strass, Simon, de Vos, Alex F., van der Poll, Tom
Published in Antimicrobial agents and chemotherapy (20.09.2022)
Published in Antimicrobial agents and chemotherapy (20.09.2022)
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Journal Article
Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia
Michels, Erik H A, Appelman, Brent, de Brabander, Justin, van Amstel, Rombout B E, van Linge, Christine C A, Chouchane, Osoul, Reijnders, Tom D Y, Schuurman, Alex R, Sulzer, Titia A L, Klarenbeek, Augustijn M, Douma, Renée A, Bos, Lieuwe D J, Wiersinga, W Joost, Peters-Sengers, Hessel, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (15.02.2024)
Published in American journal of respiratory and critical care medicine (15.02.2024)
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Journal Article
Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide
Pereverzeva, Liza, van Linge, Christine C.A., Schuurman, Alex R., Klarenbeek, Augustijn M., Ramirez Moral, Ivan, Otto, Natasja A., Peters-Sengers, Hessel, Butler, Joe M., Schomakers, Bauke V., van Weeghel, Michel, Houtkooper, Riekelt H., Wiersinga, W. Joost, Bonta, Peter I., Annema, Jouke T., de Vos, Alex F., van der Poll, Tom
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
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Age-related changes in plasma biomarkers and their association with mortality in COVID-19
Michels, Erik H A, Appelman, Brent, de Brabander, Justin, van Amstel, Rombout B E, Chouchane, Osoul, van Linge, Christine C A, Schuurman, Alex R, Reijnders, Tom D Y, Sulzer, Titia A L, Klarenbeek, Augustijn M, Douma, Renée A, Bos, Lieuwe D J, Wiersinga, W Joost, Peters-Sengers, Hessel, van der Poll, Tom, van Agtmael, Michiel, Algera, Anne Geke, Appelman, Brent, van Baarle, Floor, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Bugiani, Marianna, Bulle, Esther, Buis, David T P, Chouchane, Osoul, Cloherty, Alex, Dijkstra, Mirjam, Dongelmans, Dave A, Dujardin, Romein W G, Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M, Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W, de Jong, Hanna K, de Jong, Menno D, Koning, Rutger, Lemkes, Bregje, Lim, Endry H T, van Mourik, Niels, Nellen, Jeaninne, Nossent, Esther J, Olie, Sabine, Paulus, Frederique, Peters, Edgar, Pina-Fuentes, Dan A I, van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M, Raasveld, Jorinde, Reijnders, Tom, de Rotte, Maurits C F J, Schinkel, Michiel, Schultz, Marcus J, Schrauwen, Femke A P, Schuurman, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A, Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S, Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M, Tuinman, Pieter R, van der Valk, Marc, Veelo, Denise P, Volleman, Carolien, de Vries, Heder, Vught, Lonneke A, van Vugt, Michèle, Wouters, Dorien, Zwinderman, A H Koos, Brouwer, Matthijs C, Wiersinga, W Joost, Vlaar, Alexander P J, van de Beek, Diederik
Published in The European respiratory journal (01.07.2023)
Published in The European respiratory journal (01.07.2023)
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Journal Article
Immunostimulatory Effect of Flagellin on MDR- Klebsiella -Infected Human Airway Epithelial Cells
van Linge, Christine C A, Hulme, Katina D, Peters-Sengers, Hessel, Sirard, Jean-Claude, Goessens, Wil H F, de Jong, Menno D, Russell, Colin A, de Vos, Alex F, van der Poll, Tom
Published in International journal of molecular sciences (25.12.2023)
Published in International journal of molecular sciences (25.12.2023)
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Journal Article
Thrombocytopenia is associated with a dysregulated host response in severe COVID-19
Appelman, Brent, Michels, Erik H.A., de Brabander, Justin, Peters-Sengers, Hessel, van Amstel, Rombout B.E., Noordzij, Sophie M., Klarenbeek, Augustijn M., van Linge, Christine C.A., Chouchane, Osoul, Schuurman, Alex R., Reijnders, Tom D.Y., Douma, Renée A., Bos, Lieuwe D.J., Wiersinga, W. Joost, van der Poll, Tom
Published in Thrombosis research (01.09.2023)
Published in Thrombosis research (01.09.2023)
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Journal Article
Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward
de Brabander, Justin, Michels, Erik H A, van Linge, Christine C A, Chouchane, Osoul, Douma, Renée A, Reijnders, Tom D Y, Schuurman, Alex R, van Engelen, Tjitske S R, Wiersinga, W Joost, van der Poll, Tom
Published in Respiratory research (03.06.2022)
Published in Respiratory research (03.06.2022)
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Journal Article
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia
Schuurman, Alex R, Chouchane, Osoul, Butler, Joe M, Peters-Sengers, Hessel, Joosten, Sebastiaan, Brands, Xanthe, Haak, Bastiaan W, Otto, Natasja A, Uhel, Fabrice, Klarenbeek, Augustijn, van Linge, Christine Ca, van Kampen, Antoine, Pras-Raves, Mia, van Weeghel, Michel, van Eijk, Marco, Ferraz, Maria J, Faber, Daniël R, de Vos, Alex, Scicluna, Brendon P, Vaz, Frédéric M, Wiersinga, W Joost, van der Poll, Tom
Published in JCI insight (22.02.2024)
Published in JCI insight (22.02.2024)
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