Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo
Rafiq, Sarwish, Yeku, Oladapo O, Jackson, Hollie J, Purdon, Terence J, van Leeuwen, Dayenne G, Drakes, Dylan J, Song, Mei, Miele, Matthew M, Li, Zhuoning, Wang, Pei, Yan, Su, Xiang, Jingyi, Ma, Xiaojing, Seshan, Venkatraman E, Hendrickson, Ronald C, Liu, Cheng, Brentjens, Renier J
Published in Nature biotechnology (01.10.2018)
Published in Nature biotechnology (01.10.2018)
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CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response
Kuhn, Nicholas F., Purdon, Terence J., van Leeuwen, Dayenne G., Lopez, Andrea V., Curran, Kevin J., Daniyan, Anthony F., Brentjens, Renier J.
Published in Cancer cell (18.03.2019)
Published in Cancer cell (18.03.2019)
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Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System
Avanzi, Mauro P., Yeku, Oladapo, Li, Xinghuo, Wijewarnasuriya, Dinali P., van Leeuwen, Dayenne G., Cheung, Kenneth, Park, Hyebin, Purdon, Terence J., Daniyan, Anthony F., Spitzer, Matthew H., Brentjens, Renier J.
Published in Cell reports (Cambridge) (15.05.2018)
Published in Cell reports (Cambridge) (15.05.2018)
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Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression
Curran, Kevin J, Seinstra, Beatrijs A, Nikhamin, Yan, Yeh, Raymond, Usachenko, Yelena, van Leeuwen, Dayenne G, Purdon, Terence, Pegram, Hollie J, Brentjens, Renier J
Published in Molecular therapy (01.04.2015)
Published in Molecular therapy (01.04.2015)
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Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies
Watanabe, Norihiro, Mo, Feiyan, Zheng, Rong, Ma, Royce, Bray, Vanesa C., van Leeuwen, Dayenne G., Sritabal-Ramirez, Juntima, Hu, Hongxiang, Wang, Sha, Mehta, Birju, Srinivasan, Madhuwanti, Scherer, Lauren D., Zhang, Huimin, Thakkar, Sachin G., Hill, LaQuisa C., Heslop, Helen E., Cheng, Chonghui, Brenner, Malcolm K., Mamonkin, Maksim
Published in Molecular therapy (04.01.2023)
Published in Molecular therapy (04.01.2023)
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Safety and tolerability of conditioning chemotherapy followed by CD19-targeted CAR T cells for relapsed/refractory CLL
Geyer, Mark B, Rivière, Isabelle, Sénéchal, Brigitte, Wang, Xiuyan, Wang, Yongzeng, Purdon, Terence J, Hsu, Meier, Devlin, Sean M, Palomba, M Lia, Halton, Elizabeth, Bernal, Yvette, van Leeuwen, Dayenne G, Sadelain, Michel, Park, Jae H, Brentjens, Renier J
Published in JCI insight (02.05.2019)
Published in JCI insight (02.05.2019)
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Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity
Ma, Royce, Woods, Mae, Burkhardt, Phillip, Crooks, Noah, van Leeuwen, Dayenne G., Shmidt, Daniil, Couturier, Jacob, Chaumette, Alexandre, Popat, Divya, Hill, LaQuisa C., Rouce, Rayne H., Thakkar, Sachin, Orozco, Aaron F., Carisey, Alexandre F., Brenner, Malcolm K., Mamonkin, Maksim
Published in Cell reports. Medicine (16.07.2024)
Published in Cell reports. Medicine (16.07.2024)
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IL-18 Secreting CAR T Cells Enhance Cell Persistence, Induce Prolonged B Cell Aplasia and Eradicate CD19+ Tumor Cells without Need for Prior Conditioning
Avanzi, Mauro P., G. van Leeuwen, Dayenne, Li, Xinghuo, Cheung, Kenneth, Park, Hyebin, Purdon, Terence J., Brentjens, Renier J.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Enhancing CAR T Cell Anti-Tumor Efficacy through Secreted Single Chain Variable Fragment (scFv) Immune Checkpoint Blockade
Rafiq, Sarwish, Jackson, Hollie J., Yeku, Oladapo, Purdon, Terence J, van Leeuwen, Dayenne G., Curran, Kevin J., Ahmed, Ryan N, Cullen, Grace D, Yan, Su, Wang, Pei, Xiang, Jingyi, Liu, Cheng, Brentjens, Renier J.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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