Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx
Garsen, Marjolein, Lenoir, Olivia, Rops, Angelique L W M M, Dijkman, Henry B, Willemsen, Brigith, van Kuppevelt, Toin H, Rabelink, Ton J, Berden, Jo H M, Tharaux, Pierre-Louis, van der Vlag, Johan
Published in Journal of the American Society of Nephrology (01.12.2016)
Published in Journal of the American Society of Nephrology (01.12.2016)
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Journal Article
Chemotherapeutic drug delivery by tumoral extracellular matrix targeting
Raavé, René, van Kuppevelt, Toin H., Daamen, Willeke F.
Published in Journal of controlled release (28.03.2018)
Published in Journal of controlled release (28.03.2018)
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Journal Article
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
Christianson, Helena C., Svensson, Katrin J., van Kuppevelt, Toin H., Li, Jin-Ping, Belting, Mattias
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
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Journal Article
Interactions between Skeletal Muscle Myoblasts and their Extracellular Matrix Revealed by a Serum Free Culture System
Chaturvedi, Vishal, Dye, Danielle E, Kinnear, Beverley F, van Kuppevelt, Toin H, Grounds, Miranda D, Coombe, Deirdre R
Published in PloS one (01.06.2015)
Published in PloS one (01.06.2015)
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Journal Article
Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions
Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M, Guimond, Scott E, Eyckerman-Kölln, Pieter J, Ten Dam, Gerdy, van Kuppevelt, Toin H, Turnbull, Jeremy E, Dierks, Thomas
Published in PloS one (08.10.2015)
Published in PloS one (08.10.2015)
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Journal Article
Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis
Stachtea, Xanthi N, Tykesson, Emil, van Kuppevelt, Toin H, Feinstein, Ricardo, Malmström, Anders, Reijmers, Rogier M, Maccarana, Marco
Published in PloS one (21.10.2015)
Published in PloS one (21.10.2015)
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Journal Article
Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches
Kerever, Aurelien, Nagahara, Fumina, Keino-Masu, Kazuko, Masu, Masayuki, van Kuppevelt, Toin H, Vivès, Romain R, Arikawa-Hirasawa, Eri
Published in Glycobiology (Oxford) (18.12.2021)
Published in Glycobiology (Oxford) (18.12.2021)
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Journal Article
CGRP inhibits human Langerhans cells infection with HSV by differentially modulating specific HSV-1 and HSV-2 entry mechanisms
Cohen, Emmanuel, Mariotton, Jammy, Rozenberg, Flore, Sams, Anette, van Kuppevelt, Toin H, Barry Delongchamps, Nicolas, Zerbib, Marc, Bomsel, Morgane, Ganor, Yonatan
Published in Mucosal immunology (01.04.2022)
Published in Mucosal immunology (01.04.2022)
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Journal Article
Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritis
van Gemst, Jasper J, Passmann, Nathalie J H G, Rops, Angelique L W M M, van Kuppevelt, Toin H, Berden, Jo H, Loeven, Markus A, Rabelink, Ton J, Smeets, Bart, van der Vlag, Johan
Published in PloS one (23.12.2021)
Published in PloS one (23.12.2021)
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Journal Article
Low-GDP, pH-neutral solutions preserve peritoneal endothelial glycocalyx during long-term peritoneal dialysis
Sugiyama, Naoya, Tawada, Mitsuhiro, Sun, Ting, Suzuki, Yasuhiro, Kinashi, Hiroshi, Yamaguchi, Makoto, Katsuno, Takayuki, Aten, Jan, Vlahu, Carmen A., van Kuppevelt, Toin H., Takei, Yoshifumi, Ishimoto, Takuji, Maruyama, Shoichi, Mizuno, Masashi, Ito, Yasuhiko
Published in Clinical and experimental nephrology (01.09.2021)
Published in Clinical and experimental nephrology (01.09.2021)
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Journal Article
Evaluation and Refinement of Sample Preparation Methods for Extracellular Matrix Proteome Coverage
McCabe, Maxwell C., Schmitt, Lauren R., Hill, Ryan C., Dzieciatkowska, Monika, Maslanka, Mark, Daamen, Willeke F., van Kuppevelt, Toin H., Hof, Danique J., Hansen, Kirk C.
Published in Molecular & cellular proteomics (01.01.2021)
Published in Molecular & cellular proteomics (01.01.2021)
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Journal Article
Polarized Secretion of APRIL by the Tonsil Epithelium Upon Toll-Like Receptor Stimulation
Sturm, Nathalie, Quinterot, Melanie, Guyot, Jean-Philippe, Righini, Christian, Daamen, Willeke F, van Kuppevelt, Toin H, Huard, Bertrand
Published in Frontiers in immunology (18.08.2021)
Published in Frontiers in immunology (18.08.2021)
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Journal Article
Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling
Takashima, Yasutoshi, Keino-Masu, Kazuko, Yashiro, Hiroshi, Hara, Satoshi, Suzuki, Tomo, van Kuppevelt, Toin H, Masu, Masayuki, Nagata, Michio
Published in American journal of physiology. Renal physiology (01.03.2016)
Published in American journal of physiology. Renal physiology (01.03.2016)
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Journal Article
3-O-Sulfated Heparan Sulfate Recognized by the Antibody HS4C3 Contribute to the Differentiation of Mouse Embryonic Stem Cells via Fas Signaling
Hirano, Kazumi, Sasaki, Norihiko, Ichimiya, Tomomi, Miura, Taichi, Van Kuppevelt, Toin H, Nishihara, Shoko
Published in PloS one (16.08.2012)
Published in PloS one (16.08.2012)
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Journal Article
Hypoxic Induction of Exosome Uptake through Proteoglycan-Dependent Endocytosis Fuels the Lipid Droplet Phenotype in Glioma
Cerezo-Magaña, Myriam, Christianson, Helena C, van Kuppevelt, Toin H, Forsberg-Nilsson, Karin, Belting, Mattias
Published in Molecular cancer research (01.03.2021)
Published in Molecular cancer research (01.03.2021)
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Journal Article
Iduronic acid in chondroitin/dermatan sulfate affects directional migration of aortic smooth muscle cells
Bartolini, Barbara, Thelin, Martin A, Svensson, Lena, Ghiselli, Giancarlo, van Kuppevelt, Toin H, Malmström, Anders, Maccarana, Marco
Published in PloS one (02.07.2013)
Published in PloS one (02.07.2013)
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Journal Article
Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis
Smeets, Bart, Kuppe, Christoph, Sicking, Eva-Maria, Fuss, Astrid, Jirak, Peggy, van Kuppevelt, Toin H, Endlich, Karlhans, Wetzels, Jack F M, Gröne, Hermann-Josef, Floege, Jürgen, Moeller, Marcus J
Published in Journal of the American Society of Nephrology (01.07.2011)
Published in Journal of the American Society of Nephrology (01.07.2011)
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Journal Article
Primary ovarian carcinomas and abdominal metastasis contain 4,6-disulfated chondroitin sulfate rich regions, which provide adhesive properties to tumour cells
Vallen, Myrtille J E, Schmidt, Samuel, Oosterhof, Arie, Bulten, Johan, Massuger, Leon F A G, van Kuppevelt, Toin H
Published in PloS one (05.11.2014)
Published in PloS one (05.11.2014)
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Journal Article