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Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Derada Troletti, Claudio, Fontijn, Ruud D., Gowing, Elizabeth, Charabati, Marc, van Het Hof, Bert, Didouh, Imad, van der Pol, Susanne M. A., Geerts, Dirk, Prat, Alexandre, van Horssen, Jack, Kooij, Gijs, de Vries, Helga E.
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Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis
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Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment
Leurs, Cyra E, Podlesniy, Petar, Trullas, Ramon, Balk, Lisanne, Steenwijk, Martijn D, Malekzadeh, Arjan, Piehl, Fredrik, Uitdehaag, Bernard MJ, Killestein, Joep, van Horssen, Jack, Teunissen, CE
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Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
van Horssen, Jack, Singh, Shailender, van der Pol, Susanne, Kipp, Markus, Lim, Jamie L, Peferoen, Laura, Gerritsen, Wouter, Kooi, Evert-Jan, Witte, Maarten E, Geurts, Jeroen J G, de Vries, Helga E, Peferoen-Baert, Regina, van den Elsen, Peter J, van der Valk, Paul, Amor, Sandra
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Published in Journal of neuroinflammation (02.07.2012)
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Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
van Doorn, Ruben, Lopes Pinheiro, Melissa A, Kooij, Gijs, Lakeman, Kim, van het Hof, Bert, van der Pol, Susanne M A, Geerts, Dirk, van Horssen, Jack, van der Valk, Paul, van der Kam, Elizabeth, Ronken, Eric, Reijerkerk, Arie, de Vries, Helga E
Published in Journal of neuroinflammation (20.06.2012)
Published in Journal of neuroinflammation (20.06.2012)
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Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis
Witte, Maarten E, Mahad, Don J, Lassmann, Hans, van Horssen, Jack
Published in Trends in molecular medicine (01.03.2014)
Published in Trends in molecular medicine (01.03.2014)
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Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
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Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter
Picon, Carmen, Jayaraman, Anusha, James, Rachel, Beck, Catriona, Gallego, Patricia, Witte, Maarten E., van Horssen, Jack, Mazarakis, Nicholas D., Reynolds, Richard
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Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions
Witte, Maarten E, Bol, John G.J.M, Gerritsen, Wouter H, Valk, Paul van der, Drukarch, Benjamin, Horssen, Jack van, Wilhelmus, Micha M.M
Published in Neurobiology of disease (01.12.2009)
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The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
Alvarez, Jorge Ivan, Dodelet-Devillers, Aurore, Kebir, Hania, Ifergan, Igal, Fabre, Pierre J., Terouz, Simone, Sabbagh, Mike, Wosik, Karolina, Bourbonnière, Lyne, Bernard, Monique, van Horssen, Jack, de Vries, Helga E., Charron, Frédéric, Prat, Alexandre
Published in Science (American Association for the Advancement of Science) (23.12.2011)
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Radical changes in multiple sclerosis pathogenesis
van Horssen, Jack, Witte, Maarten E., Schreibelt, Gerty, de Vries, Helga E.
Published in Biochimica et biophysica acta (01.02.2011)
Published in Biochimica et biophysica acta (01.02.2011)
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S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis
Barateiro, Andreia, Afonso, Vera, Santos, Gisela, Cerqueira, João José, Brites, Dora, van Horssen, Jack, Fernandes, Adelaide
Published in Molecular neurobiology (01.08.2016)
Published in Molecular neurobiology (01.08.2016)
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Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration
van Olst, Lynn, Rodriguez-Mogeda, Carla, Picon, Carmen, Kiljan, Svenja, James, Rachel E., Kamermans, Alwin, van der Pol, Susanne M. A., Knoop, Lydian, Michailidou, Iliana, Drost, Evelien, Franssen, Marc, Schenk, Geert J., Geurts, Jeroen J. G., Amor, Sandra, Mazarakis, Nicholas D., van Horssen, Jack, de Vries, Helga E., Reynolds, Richard, Witte, Maarten E.
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Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status
Vogel, Daphne Y S, Vereyken, Elly J F, Glim, Judith E, Heijnen, Priscilla D A M, Moeton, Martina, van der Valk, Paul, Amor, Sandra, Teunissen, Charlotte E, van Horssen, Jack, Dijkstra, Christine D
Published in Journal of neuroinflammation (04.03.2013)
Published in Journal of neuroinflammation (04.03.2013)
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