Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements
Manfredonia, Ilaria, Nithin, Chandran, Ponce-Salvatierra, Almudena, Ghosh, Pritha, Wirecki, Tomasz K, Marinus, Tycho, Ogando, Natacha S, Snijder, Eric J, van Hemert, Martijn J, Bujnicki, Janusz M, Incarnato, Danny
Published in Nucleic Acids Research (16.12.2020)
Published in Nucleic Acids Research (16.12.2020)
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Genome-scale deconvolution of RNA structure ensembles
Morandi, Edoardo, Manfredonia, Ilaria, Simon, Lisa M., Anselmi, Francesca, van Hemert, Martijn J., Oliviero, Salvatore, Incarnato, Danny
Published in Nature methods (01.03.2021)
Published in Nature methods (01.03.2021)
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SHAPE-guided RNA structure homology search and motif discovery
Morandi, Edoardo, van Hemert, Martijn J., Incarnato, Danny
Published in Nature communications (31.03.2022)
Published in Nature communications (31.03.2022)
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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling
Treffers, Emmely E, Tas, Ali, Scholte, Florine E M, de Ru, Arnoud H, Snijder, Eric J, van Veelen, Peter A, van Hemert, Martijn J
Published in PLoS pathogens (27.02.2023)
Published in PLoS pathogens (27.02.2023)
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SARS-CoV-2-specific CD4 + and CD8 + T cell responses can originate from cross-reactive CMV-specific T cells
Pothast, Cilia R, Dijkland, Romy C, Thaler, Melissa, Hagedoorn, Renate S, Kester, Michel G D, Wouters, Anne K, Hiemstra, Pieter S, van Hemert, Martijn J, Gras, Stephanie, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Published in eLife (21.11.2022)
Published in eLife (21.11.2022)
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Usutu virus NS4A suppresses the host interferon response by disrupting MAVS signaling
Nelemans, Tessa, Tas, Ali, Kikkert, Marjolein, van Hemert, Martijn J.
Published in Virus research (01.09.2024)
Published in Virus research (01.09.2024)
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Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture
te Velthuis, Aartjan J W, van den Worm, Sjoerd H E, Sims, Amy C, Baric, Ralph S, Snijder, Eric J, van Hemert, Martijn J
Published in PLoS pathogens (04.11.2010)
Published in PLoS pathogens (04.11.2010)
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Tomatidine reduces Chikungunya virus progeny release by controlling viral protein expression
Troost-Kind, Berit, van Hemert, Martijn J, van de Pol, Denise, van der Ende-Metselaar, Heidi, Merits, Andres, Borggrewe, Malte, Rodenhuis-Zybert, Izabela A, Smit, Jolanda M
Published in PLoS neglected tropical diseases (01.11.2021)
Published in PLoS neglected tropical diseases (01.11.2021)
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Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral
Delang, Leen, Segura Guerrero, Nidya, Tas, Ali, Quérat, Gilles, Pastorino, Boris, Froeyen, Mathy, Dallmeier, Kai, Jochmans, Dirk, Herdewijn, Piet, Bello, Felio, Snijder, Eric J, de Lamballerie, Xavier, Martina, Byron, Neyts, Johan, van Hemert, Martijn J, Leyssen, Pieter
Published in Journal of antimicrobial chemotherapy (01.10.2014)
Published in Journal of antimicrobial chemotherapy (01.10.2014)
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Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors
Kovacikova, Kristina, Gorostiola González, Marina, Jones, Rhian, Reguera, Juan, Gigante, Alba, Pérez-Pérez, María-Jesús, Pürstinger, Gerhard, Moesslacher, Julia, Langer, Thierry, Jeong, Lak Shin, Delang, Leen, Neyts, Johan, Snijder, Eric J, van Westen, Gerard J P, van Hemert, Martijn J
Published in Antimicrobial agents and chemotherapy (17.06.2021)
Published in Antimicrobial agents and chemotherapy (17.06.2021)
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Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates
Scholte, Florine E M, Tas, Ali, Martina, Byron E E, Cordioli, Paolo, Narayanan, Krishna, Makino, Shinji, Snijder, Eric J, van Hemert, Martijn J
Published in PloS one (01.08.2013)
Published in PloS one (01.08.2013)
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Cyclosporin A inhibits the replication of diverse coronaviruses
de Wilde, Adriaan H, Zevenhoven-Dobbe, Jessika C, van der Meer, Yvonne, Thiel, Volker, Narayanan, Krishna, Makino, Shinji, Snijder, Eric J, van Hemert, Martijn J
Published in Journal of general virology (01.11.2011)
Published in Journal of general virology (01.11.2011)
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SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro
van Hemert, Martijn J, van den Worm, Sjoerd H E, Knoops, Kèvin, Mommaas, A Mieke, Gorbalenya, Alexander E, Snijder, Eric J
Published in PLoS pathogens (02.05.2008)
Published in PLoS pathogens (02.05.2008)
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Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication
Bardiot, Dorothée, Vangeel, Laura, Koukni, Mohamed, Arzel, Philippe, Zwaagstra, Marleen, Lyoo, Heyrhyoung, Wanningen, Patrick, Ahmad, Shamshad, Zhang, Linlin, Sun, Xinyuanyuan, Delpal, Adrien, Eydoux, Cecilia, Guillemot, Jean-Claude, Lescrinier, Eveline, Klaassen, Hugo, Leyssen, Pieter, Jochmans, Dirk, Castermans, Karolien, Hilgenfeld, Rolf, Robinson, Colin, Decroly, Etienne, Canard, Bruno, Snijder, Eric J, van Hemert, Martijn J, van Kuppeveld, Frank, Chaltin, Patrick, Neyts, Johan, De Jonghe, Steven, Marchand, Arnaud
Published in Molecules (Basel, Switzerland) (04.02.2022)
Published in Molecules (Basel, Switzerland) (04.02.2022)
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Transactivation of programmed ribosomal frameshifting by a viral protein
Li, Yanhua, Treffers, Emmely E, Napthine, Sawsan, Tas, Ali, Zhu, Longchao, Sun, Zhi, Bell, Susanne, Mark, Brian L, van Veelen, Peter A, van Hemert, Martijn J, Firth, Andrew E, Brierley, Ian, Snijder, Eric J, Fang, Ying
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
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Dynamics of Chikungunya Virus Cell Entry Unraveled by Single-Virus Tracking in Living Cells
Hoornweg, Tabitha E, van Duijl-Richter, Mareike K S, Ayala Nuñez, Nilda V, Albulescu, Irina C, van Hemert, Martijn J, Smit, Jolanda M
Published in Journal of virology (01.05.2016)
Published in Journal of virology (01.05.2016)
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R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis
Thaler, Melissa, Salgado-Benvindo, Clarisse, Leijs, Anouk, Tas, Ali, Ninaber, Dennis K, Arbiser, Jack L, Snijder, Eric J, van Hemert, Martijn J
Published in International journal of molecular sciences (27.02.2023)
Published in International journal of molecular sciences (27.02.2023)
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Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection
Albulescu, Irina C, White-Scholten, Leonie, Tas, Ali, Hoornweg, Tabitha E, Ferla, Salvatore, Kovacikova, Kristina, Smit, Jolanda M, Brancale, Andrea, Snijder, Eric J, van Hemert, Martijn J
Published in Viruses (17.03.2020)
Published in Viruses (17.03.2020)
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