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Published in American journal of human genetics (07.07.2016)
Published in American journal of human genetics (07.07.2016)
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Fine-scale population structure and demographic history of British Pakistanis
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Published in Nature communications (10.12.2021)
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Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
Hodgson, Sam, Huang, Qin Qin, Sallah, Neneh, Griffiths, Chris J, Newman, William G, Trembath, Richard C, Wright, John, Lumbers, R Thomas, Kuchenbaecker, Karoline, van Heel, David A, Mathur, Rohini, Martin, Hilary C, Finer, Sarah
Published in PLoS medicine (19.05.2022)
Published in PLoS medicine (19.05.2022)
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CYP2C19 loss-of-function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort
Magavern, Emma F, van Heel, David A, Smedley, Damian, Caulfield, Mark J
Published in British journal of clinical pharmacology (01.11.2023)
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Inflammatory Skin and Bowel Disease Linked to ADAM17 Deletion
Blaydon, Diana C, Biancheri, Paolo, Di, Wei-Li, Plagnol, Vincent, Cabral, Rita M, Brooke, Matthew A, van Heel, David A, Ruschendorf, Franz, Toynbee, Mark, Walne, Amanda, O'Toole, Edel A, Martin, Joanne E, Lindley, Keith, Vulliamy, Tom, Abrams, Dominic J, MacDonald, Thomas T, Harper, John I, Kelsell, David P
Published in The New England journal of medicine (20.10.2011)
Published in The New England journal of medicine (20.10.2011)
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Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology
Ludvigsson, Jonas F, Bai, Julio C, Biagi, Federico, Card, Timothy R, Ciacci, Carolina, Ciclitira, Paul J, Green, Peter H R, Hadjivassiliou, Marios, Holdoway, Anne, van Heel, David A, Kaukinen, Katri, Leffler, Daniel A, Leonard, Jonathan N, Lundin, Knut E A, McGough, Norma, Davidson, Mike, Murray, Joseph A, Swift, Gillian L, Walker, Marjorie M, Zingone, Fabiana, Sanders, David S
Published in Gut (01.08.2014)
Published in Gut (01.08.2014)
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Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria
McGregor, Tracy L, Hunt, Karen A, Yee, Elaine, Mason, Dan, Nioi, Paul, Ticau, Simina, Pelosi, Marissa, Loken, Perry R, Finer, Sarah, Lawlor, Deborah A, Fauman, Eric B, Huang, Qin Qin, Griffiths, Christopher J, MacArthur, Daniel G, Trembath, Richard C, Oglesbee, Devin, Lieske, John C, Erbe, David V, Wright, John, van Heel, David A
Published in eLife (24.03.2020)
Published in eLife (24.03.2020)
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A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease
Festen, Eleonora A M, Goyette, Philippe, Green, Todd, Boucher, Gabrielle, Beauchamp, Claudine, Trynka, Gosia, Dubois, Patrick C, Lagacé, Caroline, Stokkers, Pieter C F, Hommes, Daan W, Barisani, Donatella, Palmieri, Orazio, Annese, Vito, van Heel, David A, Weersma, Rinse K, Daly, Mark J, Wijmenga, Cisca, Rioux, John D
Published in PLoS genetics (01.01.2011)
Published in PLoS genetics (01.01.2011)
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Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
Gutierrez-Achury, Javier, Zhernakova, Alexandra, Pulit, Sara L, Trynka, Gosia, Hunt, Karen A, Romanos, Jihane, Raychaudhuri, Soumya, van Heel, David A, Wijmenga, Cisca, de Bakker, Paul I W
Published in Nature genetics (01.06.2015)
Published in Nature genetics (01.06.2015)
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Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people
Finer, Sarah, Martin, Hilary C, Khan, Ahsan, Hunt, Karen A, MacLaughlin, Beverley, Ahmed, Zaheer, Ashcroft, Richard, Durham, Ceri, MacArthur, Daniel G, McCarthy, Mark I, Robson, John, Trivedi, Bhavi, Griffiths, Chris, Wright, John, Trembath, Richard C, van Heel, David A
Published in International journal of epidemiology (01.02.2020)
Published in International journal of epidemiology (01.02.2020)
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Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals
Huang, Qin Qin, Sallah, Neneh, Dunca, Diana, Trivedi, Bhavi, Hunt, Karen A, Hodgson, Sam, Lambert, Samuel A, Arciero, Elena, Wright, John, Griffiths, Chris, Trembath, Richard C, Hemingway, Harry, Inouye, Michael, Finer, Sarah, van Heel, David A, Lumbers, R Thomas, Martin, Hilary C, Kuchenbaecker, Karoline
Published in Nature communications (09.08.2022)
Published in Nature communications (09.08.2022)
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Mutations in CSTA, Encoding Cystatin A, Underlie Exfoliative Ichthyosis and Reveal a Role for This Protease Inhibitor in Cell-Cell Adhesion
Blaydon, Diana C., Nitoiu, Daniela, Eckl, Katja-Martina, Cabral, Rita M., Bland, Philip, Hausser, Ingrid, van Heel, David A., Rajpopat, Shefali, Fischer, Judith, Oji, Vinzenz, Zvulunov, Alex, Traupe, Heiko, Hennies, Hans Christian, Kelsell, David P.
Published in American journal of human genetics (07.10.2011)
Published in American journal of human genetics (07.10.2011)
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Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
Smyth, Deborah J, Plagnol, Vincent, Walker, Neil M, Cooper, Jason D, Downes, Kate, Yang, Jennie H.M, Howson, Joanna M.M, Stevens, Helen, McManus, Ross, Wijmenga, Cisca, Heap, Graham A, Dubois, Patrick C, Clayton, David G, Hunt, Karen A, van Heel, David A, Todd, John A
Published in The New England journal of medicine (25.12.2008)
Published in The New England journal of medicine (25.12.2008)
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Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms
Monsuur, Alienke J, de Bakker, Paul I W, Zhernakova, Alexandra, Pinto, Dalila, Verduijn, Willem, Romanos, Jihane, Auricchio, Renata, Lopez, Ana, van Heel, David A, Crusius, J Bart A, Wijmenga, Cisca
Published in PloS one (28.05.2008)
Published in PloS one (28.05.2008)
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Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes
Narasimhan, Vagheesh M, Rahbari, Raheleh, Scally, Aylwyn, Wuster, Arthur, Mason, Dan, Xue, Yali, Wright, John, Trembath, Richard C, Maher, Eamonn R, van Heel, David A, Auton, Adam, Hurles, Matthew E, Tyler-Smith, Chris, Durbin, Richard
Published in Nature communications (21.08.2017)
Published in Nature communications (21.08.2017)
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Novel Association in Chromosome 4q27 Region with Rheumatoid Arthritis and Confirmation of Type 1 Diabetes Point to a General Risk Locus for Autoimmune Diseases
Zhernakova, Alexandra, Alizadeh, Behrooz Z., Bevova, Marianna, van Leeuwen, Miek A., Coenen, Marieke J.H., Franke, Barbara, Franke, Lude, Posthumus, Marcel D., van Heel, David A., van der Steege, Gerrit, Radstake, Timothy R.D.J., Barrera, Pilar, Roep, Bart O., Koeleman, Bobby P.C., Wijmenga, Cisca
Published in American journal of human genetics (01.12.2007)
Published in American journal of human genetics (01.12.2007)
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Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants
Romanos, Jihane, Rosén, Anna, Kumar, Vinod, Trynka, Gosia, Franke, Lude, Szperl, Agata, Gutierrez-Achury, Javier, van Diemen, Cleo C, Kanninga, Roan, Jankipersadsing, Soesma A, Steck, Andrea, Eisenbarth, Georges, van Heel, David A, Cukrowska, Bozena, Bruno, Valentina, Mazzilli, Maria Cristina, Núñez, Concepcion, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Rewers, Marian, Norris, Jill M, Ivarsson, Anneli, Boezen, H Marieke, Liu, Edwin, Wijmenga, Cisca
Published in Gut (01.03.2014)
Published in Gut (01.03.2014)
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A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care
Sharp, Seth A., Jones, Samuel E., Kimmitt, Robert A., Weedon, Michael N., Halpin, Anne M., Wood, Andrew R., Beaumont, Robin N., King, Seema, Heel, David A., Campbell, Patricia M., Hagopian, William A., Turner, Justine M., Oram, Richard A
Published in Alimentary pharmacology & therapeutics (01.10.2020)
Published in Alimentary pharmacology & therapeutics (01.10.2020)
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A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
van Heel, David A, Franke, Lude, Hunt, Karen A, Gwilliam, Rhian, Zhernakova, Alexandra, Inouye, Mike, Wapenaar, Martin C, Barnardo, Martin C N M, Bethel, Graeme, Holmes, Geoffrey K T, Feighery, Con, Jewell, Derek, Kelleher, Dermot, Kumar, Parveen, Travis, Simon, Walters, Julian RF, Sanders, David S, Howdle, Peter, Swift, Jill, Playford, Raymond J, McLaren, William M, Mearin, M Luisa, Mulder, Chris J, McManus, Ross, McGinnis, Ralph, Cardon, Lon R, Deloukas, Panos, Wijmenga, Cisca
Published in Nature genetics (01.07.2007)
Published in Nature genetics (01.07.2007)
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