Targeted temperature management after cardiac arrest is associated with reduced metabolism of pantoprazole – A probe drug of CYP2C19 metabolism
Poppe, Michael, Clodi, Christian, Schriefl, Christoph, Mueller, Matthias, Sunder-Plaßmann, Raute, Reiter, Birgit, Rechenmacher, Maximilian, van Os, Wisse, van Hasselt, J.G. Coen, Holzer, Michael, Herkner, Harald, Schwameis, Michael, Jilma, Bernd, Schoergenhofer, Christian, Weiser, Christoph
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Journal Article
Time Dependent Resource Use and Costs Associated with Different States of Disease in Patients Diagnosed with HER-2 Positive Metastatic Breast Cancer
Frederix, G.W, Severens, J.L, Hövels, A.M, van Hasselt, J.G, Raaijmakers, J.A, Schellens, J.H
Published in Value in health (01.11.2013)
Published in Value in health (01.11.2013)
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Journal Article
Differential metabolic host response to pathogens associated with community-acquired pneumonia
den Hartog, Ilona, Karu, Naama, Zwep, Laura B., Voorn, G. Paul, van de Garde, Ewoudt M.W., Hankemeier, Thomas, van Hasselt, J.G. Coen
Published in Metabolism open (01.06.2023)
Published in Metabolism open (01.06.2023)
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Journal Article
PRM46 Development of a Framework for Cost-Effectiveness Analysis Cohort Simulation Using an Ordinary Differential Equation Solver Algorithm in R
Frederix, G.W, van Hasselt, J.G, Severens, J.L, Hövels, A.M, Huitema, A.D, Raaijmakers, J.A, Schellens, J.H
Published in Value in health (01.11.2012)
Published in Value in health (01.11.2012)
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Journal Article
MO2 Impact of Structural Assumptions on Cost-Effectiveness Outcomes: Towards a Standardized Cost-Effectiveness Model for Adjuvant Breast Cancer Therapies
Frederix, G.W, Van hasselt, J.G, Schellens, J.H, Hövels, A.M, Huitema, A.D, Raaijmakers, J.A, Severens, J
Published in Value in health (01.11.2012)
Published in Value in health (01.11.2012)
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Journal Article
Crowdsourced Asparagus Urinary Odor Population Kinetics
Ramamoorthy, Anuradha, Sadler, Brian M., van Hasselt, J.G. Coen, Elassaiss‐Schaap, Jeroen, Kasichayanula, Sreeneeranj, Edwards, Alena Y., van der Graaf, Piet H., Zhang, Lei, Wagner, John A.
Published in CPT: pharmacometrics and systems pharmacology (01.01.2018)
Published in CPT: pharmacometrics and systems pharmacology (01.01.2018)
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Journal Article
Systems Pharmacology: Defining the Interactions of Drug Combinations
van Hasselt, J.G. Coen, Iyengar, Ravi
Published in Annual review of pharmacology and toxicology (06.01.2019)
Published in Annual review of pharmacology and toxicology (06.01.2019)
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Journal Article
Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine
Kohler, Isabelle, Hankemeier, Thomas, van der Graaf, Piet H., Knibbe, Catherijne A.J., van Hasselt, J.G. Coen
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Journal Article
Biomarker‐Guided Individualization of Antibiotic Therapy
Aulin, Linda B.S., Lange, Dylan W., Saleh, Mohammed A.A., Graaf, Piet H., Völler, Swantje, Hasselt, J.G. Coen
Published in Clinical pharmacology and therapeutics (01.08.2021)
Published in Clinical pharmacology and therapeutics (01.08.2021)
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Journal Article
Integrative model-based comparison of target site-specific antimicrobial effects: A case study with ceftaroline and lefamulin
van Os, Wisse, Pham, Anh Duc, Eberl, Sabine, Minichmayr, Iris K., van Hasselt, J.G. Coen, Zeitlinger, Markus
Published in International journal of antimicrobial agents (01.05.2024)
Published in International journal of antimicrobial agents (01.05.2024)
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Journal Article
Evidence-based drug treatment for special patient populations through model-based approaches
Krekels, Elke H.J., van Hasselt, J.G. Coen, van den Anker, John N., Allegaert, Karel, Tibboel, Dick, Knibbe, Catherijne A.J.
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Journal Article
Renal function, body surface area, and age are associated with risk of early-onset fluoropyrimidine-associated toxicity in patients treated with capecitabine-based anticancer regimens in daily clinical care
Meulendijks, Didier, van Hasselt, J.G. Coen, Huitema, Alwin D.R, van Tinteren, Harm, Deenen, Maarten J, Beijnen, Jos H, Cats, Annemieke, Schellens, Jan H.M
Published in European journal of cancer (1990) (01.02.2016)
Published in European journal of cancer (1990) (01.02.2016)
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Journal Article
Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects
Antunes, Natalicia de Jesus, van Dijkman, Sven C., Lanchote, Vera Lucia, Wichert-Ana, Lauro, Coelho, Eduardo Barbosa, Alexandre Junior, Veriano, Takayanagui, Osvaldo Massaiti, Tozatto, Eduardo, van Hasselt, J.G. Coen, Della Pasqua, Oscar
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Journal Article
Towards personalized treatment of pain using a quantitative systems pharmacology approach
Goulooze, Sebastiaan C., Krekels, Elke H.J., van Dijk, Monique, Tibboel, Dick, van der Graaf, Piet H., Hankemeier, Thomas, Knibbe, Catherijne A.J., van Hasselt, J.G. Coen
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Journal Article
Towards integrative systems pharmacology models in oncology drug development
van Hasselt, J.G. Coen, van der Graaf, Piet H.
Published in Drug discovery today. Technologies (01.08.2015)
Published in Drug discovery today. Technologies (01.08.2015)
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Journal Article
PRM19 - Time Dependent Resource Use and Costs Associated with Different States of Disease in Patients Diagnosed with HER-2 Positive Metastatic Breast Cancer
Frederix, G.W., Severens, J.L., Hövels, A.M., van Hasselt, J.G., Raaijmakers, J.A., Schellens, J.H.
Published in Value in health (01.11.2013)
Published in Value in health (01.11.2013)
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Journal Article
Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy
van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Published in BioMed research international (01.01.2014)
Published in BioMed research international (01.01.2014)
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Journal Article