Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation
Angelidou, Asimenia, Conti, Maria-Giulia, Diray-Arce, Joann, Benn, Christine S., Shann, Frank, Netea, Mihai G., Liu, Mark, Potluri, Lakshmi Prasad, Sanchez-Schmitz, Guzman, Husson, Robert, Ozonoff, Al, Kampmann, Beate, van Haren, Simon Daniël, Levy, Ofer
Published in Vaccine (24.02.2020)
Published in Vaccine (24.02.2020)
Get full text
Journal Article
BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny
Angelidou, Asimenia, Diray-Arce, Joann, Conti, Maria Giulia, Smolen, Kinga K, van Haren, Simon Daniël, Dowling, David J, Husson, Robert N, Levy, Ofer
Published in Frontiers in microbiology (11.03.2020)
Published in Frontiers in microbiology (11.03.2020)
Get full text
Journal Article
Soluble mediators regulating immunity in early life
Pettengill, Matthew Aaron, van Haren, Simon Daniël, Levy, Ofer
Published in Frontiers in immunology (24.09.2014)
Published in Frontiers in immunology (24.09.2014)
Get full text
Journal Article
Precision immunology for discovery and development of the Precision Vaccines Program (PVP)-037 small molecule series: imidazopyrimidine adjuvants identified via age-specific human in vitro modeling
Soni, Dheeraj, Borriello, Francesco, Scott, David A, Ozonoff, Al, Brightman, Spencer, Smith, Jennifer, Shamu, Caroline, Ramirez, Juan C, Baden, Lindsey Robert, Cheng, Wing Ki, van Haren, Simon Daniel, Pettengill, Matthew, Dowling, David J, Levy, Ofer
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
Get full text
Journal Article
From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation
Soni, Dheeraj, Borriello, Francesco, Scott, David A, Feru, Frederic, DeLeon, Maria, Brightman, Spencer E, Cheng, Wing Ki, Melhem, Gandolina, Smith, Jennifer A, Ramirez, Juan C, Barman, Soumik, Cameron, Michael, Kelly, Aisling, Walker, Kristina, Nanishi, Etsuro, van Haren, Simon Daniel, Phan, Tony, Qi, Yizhi, Kinsey, Robert, Raczy, Michal M, Ozonoff, Al, Pettengill, Matthew A, Hubbell, Jeffery A, Fox, Christopher B, Dowling, David J, Levy, Ofer
Published in Science advances (05.07.2024)
Published in Science advances (05.07.2024)
Get full text
Journal Article
A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity
Dowling, David J, Sanders, Holly, Cheng, Wing Ki, Joshi, Sweta, Brightman, Spencer, Bergelson, Ilana, Pietrasanta, Carlo, van Haren, Simon D, van Amsterdam, Sandra, Fernandez, Jeffrey, van den Dobbelsteen, Germie P J M, Levy, Ofer
Published in Frontiers in immunology (08.12.2016)
Published in Frontiers in immunology (08.12.2016)
Get full text
Journal Article