Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics
Wagner, Jonathan B, Abdel-Rahman, Susan, Van Haandel, Leon, Gaedigk, Andrea, Gaedigk, Roger, Raghuveer, Geetha, Kauffman, Ralph, Leeder, J Steven
Published in Journal of clinical pharmacology (01.06.2018)
Published in Journal of clinical pharmacology (01.06.2018)
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Journal Article
Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
Zhang, Li Q, Van Haandel, Leon, Xiong, Min, Huang, Peixin, Heruth, Daniel P, Bi, Charlie, Gaedigk, Roger, Jiang, Xun, Li, Ding-You, Wyckoff, Gerald, Grigoryev, Dmitry N, Gao, Li, Li, Linheng, Wu, Min, Leeder, J Steven, Ye, Shui Qing
Published in Cell death & disease (23.03.2017)
Published in Cell death & disease (23.03.2017)
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Journal Article
In Vitro Hepatic Oxidative Biotransformation of Trimethoprim
Goldman, Jennifer L, Leeder, J Steven, Van Haandel, Leon, Pearce, Robin E
Published in Drug metabolism and disposition (01.09.2015)
Published in Drug metabolism and disposition (01.09.2015)
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Journal Article
Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study
van Haandel, Leon, Gibson, Kim T., Leeder, J. Steven, Wagner, Jonathan B.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2016)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2016)
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Journal Article
Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease
Morrow, Ryan, Funk, Ryan, Becker, Mara, Sherman, Ashley, Van Haandel, Leon, Hudson, Taina, Casini, Rebecca, Shakhnovich, Valentina
Published in Pharmaceuticals (Basel, Switzerland) (14.05.2021)
Published in Pharmaceuticals (Basel, Switzerland) (14.05.2021)
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Journal Article
The benzylic alcohol metabolite of trimethoprim covalently binds to proteins in vitro
Goldman, Jennifer L., Leeder, J. Steven, van Haandel, Leon
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Journal Article
Impact of SLCO1B1 Genetic Variation on Rosuvastatin Systemic Exposure in Pediatric Hypercholesterolemia
Wagner, Jonathan B., Abdel‐Rahman, Susan, Gaedigk, Andrea, Gaedigk, Roger, Raghuveer, Geetha, Staggs, Vincent S., Van Haandel, Leon, Leeder, J. Steven
Published in Clinical and translational science (01.05.2020)
Published in Clinical and translational science (01.05.2020)
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Journal Article
Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line
Funk, Ryan S, van Haandel, Leon, Becker, Mara L, Leeder, J Steven
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
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Journal Article
Evidence of circulating trimethoprim protein adducts in human plasma
van Haandel, Leon, Funk, Ryan, Leeder, J. Steven, Goldman, Jennifer L.
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Journal Article
Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability
Becker, Mara L, van Haandel, Leon, Gaedigk, Roger, Thomas, Bradley, Hoeltzel, Mark F, Lasky, Andrew, Dai, Hongying, Stobaugh, John, Leeder, James S
Published in Pharmacogenetics and genomics (01.04.2012)
Published in Pharmacogenetics and genomics (01.04.2012)
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Journal Article
A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells
van Haandel, Leon, Becker, Mara L., Leeder, J. Steven, Williams, Todd D., Stobaugh, John F.
Published in Rapid communications in mass spectrometry (15.12.2009)
Published in Rapid communications in mass spectrometry (15.12.2009)
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Journal Article
Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS
van Haandel, Leon, Becker, Mara L, Williams, T D, Leeder, J Steven, Stobaugh, John F
Published in Bioanalysis (01.12.2011)
Published in Bioanalysis (01.12.2011)
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Journal Article
Intracellular folate concentrations in Down syndrome patients with arthritis
Becker, Mara L, van Haandel, Leon, Talib, Nasreen, Lasky, Andrew, Hoeltzel, Mark F, Leeder, J Steven
Published in Pediatric rheumatology online journal (13.07.2012)
Published in Pediatric rheumatology online journal (13.07.2012)
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Journal Article