Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML
Oki, Toshihiko, Mercier, Francois, Kato, Hiroki, Jung, Yookyung, McDonald, Thomas O., Spencer, Joel A., Mazzola, Michael C., van Gastel, Nick, Lin, Charles P., Michor, Franziska, Kitamura, Toshio, Scadden, David T.
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Uncovering the periosteum for skeletal regeneration: The stem cell that lies beneath
Roberts, Scott J, van Gastel, Nick, Carmeliet, Geert, Luyten, Frank P
Published in Bone (New York, N.Y.) (01.01.2015)
Published in Bone (New York, N.Y.) (01.01.2015)
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HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival
Stegen, Steve, van Gastel, Nick, Eelen, Guy, Ghesquière, Bart, D’Anna, Flora, Thienpont, Bernard, Goveia, Jermaine, Torrekens, Sophie, Van Looveren, Riet, Luyten, Frank P., Maxwell, Patrick H., Wielockx, Ben, Lambrechts, Diether, Fendt, Sarah-Maria, Carmeliet, Peter, Carmeliet, Geert
Published in Cell metabolism (09.02.2016)
Published in Cell metabolism (09.02.2016)
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Oxygen as a critical determinant of bone fracture healing—A multiscale model
Carlier, Aurélie, Geris, Liesbet, Gastel, Nick van, Carmeliet, Geert, Oosterwyck, Hans Van
Published in Journal of theoretical biology (21.01.2015)
Published in Journal of theoretical biology (21.01.2015)
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Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle
Tournaire, Guillaume, Loopmans, Shauni, Stegen, Steve, Rinaldi, Gianmarco, Eelen, Guy, Torrekens, Sophie, Moermans, Karen, Carmeliet, Peter, Ghesquière, Bart, Thienpont, Bernard, Fendt, Sarah-Maria, van Gastel, Nick, Carmeliet, Geert
Published in Cell reports (Cambridge) (26.07.2022)
Published in Cell reports (Cambridge) (26.07.2022)
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Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers
Chai, Yoke Chin, Roberts, Scott J, Desmet, Eline, Kerckhofs, Greet, van Gastel, Nick, Geris, Liesbet, Carmeliet, Geert, Schrooten, Jan, Luyten, Frank P
Published in Biomaterials (01.04.2012)
Published in Biomaterials (01.04.2012)
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Size does matter: an integrative in vivo-in silico approach for the treatment of critical size bone defects
Carlier, Aurélie, van Gastel, Nick, Geris, Liesbet, Carmeliet, Geert, Van Oosterwyck, Hans
Published in PLoS computational biology (01.11.2014)
Published in PLoS computational biology (01.11.2014)
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Metabolic crosstalk between stromal and malignant cells in the bone marrow niche
Tirado, Hernán A., Balasundaram, Nithya, Laaouimir, Lotfi, Erdem, Ayşegül, van Gastel, Nick
Published in Bone Reports (01.06.2023)
Published in Bone Reports (01.06.2023)
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Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways
Manesia, Javed K., Xu, Zhuofei, Broekaert, Dorien, Boon, Ruben, van Vliet, Alex, Eelen, Guy, Vanwelden, Thomas, Stegen, Steve, Van Gastel, Nick, Pascual-Montano, Alberto, Fendt, Sarah-Maria, Carmeliet, Geert, Carmeliet, Peter, Khurana, Satish, Verfaillie, Catherine M.
Published in Stem cell research (01.11.2015)
Published in Stem cell research (01.11.2015)
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Analysis of Leukemia Cell Metabolism through Stable Isotope Tracing in Mice
van Gastel, Nick, Spinelli, Jessica B, Haigis, Marcia C, Scadden, David T
Published in Bio-protocol (05.10.2021)
Published in Bio-protocol (05.10.2021)
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An Ectopic Imaging Window for Intravital Imaging of Engineered Bone Tissue
Stiers, Pieter-Jan, van Gastel, Nick, Moermans, Karen, Stockmans, Ingrid, Carmeliet, Geert
Published in JBMR plus (01.03.2018)
Published in JBMR plus (01.03.2018)
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Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved
Dauwe, Dieter, Pelacho, Beatriz, Wibowo, Arief, Walravens, Ann‐Sophie, Verdonck, Kristoff, Gillijns, Hilde, Caluwe, Ellen, Pokreisz, Peter, Gastel, Nick, Carmeliet, Geert, Depypere, Maarten, Maes, Frederik, Vanden Driessche, Nina, Droogne, Walter, Van Cleemput, Johan, Vanhaecke, Johan, Prosper, Felipe, Verfaillie, Catherine, Luttun, Aernout, Janssens, Stefan
Published in Journal of the American Heart Association (18.04.2016)
Published in Journal of the American Heart Association (18.04.2016)
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3029 – MITOCHONDRIAL REGULATION OF CELL FATE THROUGH BIOGENESIS OF EXTRACELLULAR VESICLES IN HSC
Bonora, Massimo, Morganti, Claudia, Van Gastel, Nick, Ito, Keisuke
Published in Experimental hematology (01.08.2024)
Published in Experimental hematology (01.08.2024)
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