CD4 Donor Lymphocyte Infusion Can Cause Conversion of Chimerism Without GVHD by Inducing Immune Responses Targeting Minor Histocompatibility Antigens in HLA Class II
van Balen, Peter, van Bergen, Cornelis A M, van Luxemburg-Heijs, Simone A P, de Klerk, Wendy, van Egmond, Esther H M, Veld, Sabrina A J, Halkes, Constantijn J M, Zwaginga, Jaap-Jan, Griffioen, Marieke, Jedema, Inge, Falkenburg, J H Frederik
Published in Frontiers in immunology (18.12.2018)
Published in Frontiers in immunology (18.12.2018)
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Impact of alemtuzumab pharmacokinetics on T-cell dynamics, graft-versus-host disease and viral reactivation in patients receiving allogeneic stem cell transplantation with an alemtuzumab-based T-cell-depleted graft
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Published in Transplant immunology (01.12.2019)
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Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression
Loeff, Floris C., Rijs, Kevin, Egmond, Esther H. M., Zoutman, Willem H., Qiao, Xiaohang, Kroes, Wilhelmina G. M., Veld, Sabrina A. J., Griffioen, Marieke, Vermeer, Maarten H., Neefjes, Jacques, Frederik Falkenburg, J. H., Halkes, Constantijn J. M., Jedema, Inge
Published in American journal of hematology (01.01.2019)
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Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies
VAN LOENEN, Marleen M, DE BOER, Renate, HAGEDOORN, Renate S, VAN EGMOND, Esther H. M, FREDERIK FALKENBURG, J. H, HEEMSKERK, Mirjam H. M
Published in Haematologica (Roma) (01.03.2011)
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Competitive Repopulation and Allo-Immunologic Pressure Determine Chimerism Kinetics after T Cell-Depleted Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion
Koster, Eva A.S., von dem Borne, Peter A., van Balen, Peter, van Egmond, Esther H.M., Marijt, Erik W.A., Veld, Sabrina A.J., Jedema, Inge, Snijders, Tjeerd J.F., van Lammeren, Daniëlle, Veelken, Hendrik, Falkenburg, J.H. Frederik, de Wreede, Liesbeth C., Halkes, Constantijn J.M.
Published in Transplantation and cellular therapy (01.04.2023)
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Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application
Griffioen, Marieke, van Egmond, H.M. Esther, Barnby-Porritt, Helen, van der Hoorn, Menno A.W.G, Hagedoorn, Renate S, Kester, Michel G.D, Schwabe, Nikolai, Willemze, Roel, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M
Published in Haematologica (Roma) (01.10.2008)
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Rapid re-expression of retrovirally introduced versus endogenous TCRs in engineered T cells after antigen-specific stimulation
van Loenen, Marleen M, Hagedoorn, Renate S, de Boer, Renate, van Egmond, Esther H M, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Published in Journal of immunotherapy (1997) (01.03.2011)
Published in Journal of immunotherapy (1997) (01.03.2011)
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Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation—a phase I/II study
Roex, Marthe C. J., van Balen, Peter, Germeroth, Lothar, Hageman, Lois, van Egmond, Esther, Veld, Sabrina A. J., Hoogstraten, Conny, van Liempt, Ellis, Zwaginga, Jaap J., de Wreede, Liesbeth C., Meij, Pauline, Vossen, Ann C. T. M., Danhof, Sophia, Einsele, Hermann, Schaafsma, M. Ron, Veelken, Hendrik, Halkes, Constantijn J. M., Jedema, Inge, Falkenburg, J. H. Frederik
Published in Leukemia (01.03.2020)
Published in Leukemia (01.03.2020)
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Up-regulated expression in nonhematopoietic tissues of the BCL2A1-derived minor histocompatibility antigens in response to inflammatory cytokines: relevance for allogeneic immunotherapy of leukemia
Kloosterboer, Freke M., van Luxemburg-Heijs, Simone A.P., van Soest, Ronald A., van Egmond, H.M. Esther, Willemze, Roel, Falkenburg, J.H. Frederik
Published in Blood (01.12.2005)
Published in Blood (01.12.2005)
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High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor - /CD52 - T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell-Depleted Allogeneic Stem Cell Transplantation
Loeff, Floris C, Falkenburg, J H Frederik, Hageman, Lois, Huisman, Wesley, Veld, Sabrina A J, van Egmond, H M Esther, van de Meent, Marian, von dem Borne, Peter A, Veelken, Hendrik, Halkes, Constantijn J M, Jedema, Inge
Published in The Journal of immunology (1950) (15.03.2018)
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Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors
Loeff, Floris C., van Egmond, H. M. Esther, Nijmeijer, Bart A., Falkenburg, J. H. Frederik, Halkes, Constantijn J., Jedema, Inge
Published in Leukemia & lymphoma (02.09.2017)
Published in Leukemia & lymphoma (02.09.2017)
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A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity
Roex, Marthe C.J., Hageman, Lois, Veld, Sabrina A.J., van Egmond, Esther, Hoogstraten, Conny, Stemberger, Christian, Germeroth, Lothar, Einsele, Hermann, Falkenburg, J. H. Frederik, Jedema, Inge
Published in Blood (23.07.2020)
Published in Blood (23.07.2020)
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Effective treatment of refractory CMV reactivation after allogeneic stem cell transplantation with in vitro-generated CMV pp65-specific CD8+ T-cell lines
Meij, Pauline, Jedema, Inge, Zandvliet, Maarten L, van der Heiden, Pim L J, van de Meent, Marian, van Egmond, H M Esther, van Liempt, Ellis, Hoogstraten, Conny, Kruithof, Simone, Veld, Sabrina, Marijt, Erik W A, von dem Borne, Peter A, Lankester, Arjan C, Halkes, Constantijn J M, Falkenburg, J H Frederik
Published in Journal of immunotherapy (1997) (01.10.2012)
Published in Journal of immunotherapy (1997) (01.10.2012)
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Prophylactic Infusion of Multi-Antigen Specific T-Cell Products to Prevent Complications after T Cell Depleted Allogeneic Stem Cell Transplantation — a Phase I/II Study
Roex, Marthe C.J., Balen, Peter van, Germeroth, Lothar, Hageman, Lois, van Egmond, Esther, Veld, Sabrina A.J., Hoogstraten, Conny, van Liempt, Ellis, Zwaginga, Jaap J., de Wreede, Liesbeth C., Einsele, Hermann, Veelken, Hendrik, Halkes, Constantijn J.M., Jedema, Inge, Falkenburg, J.H. Frederik
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Effect of alemtuzumab-based T-cell depletion on graft compositional change in vitro and immune reconstitution early after allogeneic stem cell transplantation
Roex, Marthe C.J., Wijnands, Charissa, Veld, Sabrina A.J., van Egmond, Esther, Bogers, Lisette, Zwaginga, Jaap J., Netelenbos, Tanja, von dem Borne, Peter A., Veelken, Hendrik, Halkes, Constantijn J.M., Falkenburg, J.H. Frederik, Jedema, Inge
Published in Cytotherapy (Oxford, England) (01.01.2021)
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Functional Analysis of Killer Ig-Like Receptor-Expressing Cytomegalovirus-Specific CD8+ T Cells
van der Veken, Lars T, Diez Campelo, Maria, van der Hoorn, Menno A. W. G, Hagedoorn, Renate S, van Egmond, H. M. Esther, van Bergen, Jeroen, Willemze, Roel, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M
Published in The Journal of immunology (1950) (01.01.2009)
Published in The Journal of immunology (1950) (01.01.2009)
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Prevention of Viral Infections after T Cell Depleted Allogeneic Stem Cell Transplantation By Infusion of Multi-Antigen Specific T Cell Products
Roex, Marthe C.J., Balen, Peter Van, Hageman, Lois, Van Egmond, Esther, Veld, Sabrina A.J., Hoogstraten, Conny, van Liempt, Ellis, Germeroth, Lothar, Einsele, Hermann, Halkes, Constantijn J.M., Jedema, Inge, Falkenburg, J.H. Frederik
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Effectivity Of Complement-Dependent Cytotoxicity Induced By Therapeutic Antibodies In Acute Lymphoblastic Leukemia Is Dictated By Antigen Expression Levels and Curtailed By Membrane-Bound Complement Regulatory Proteins
Loeff, Floris C, van Egmond, Esther H.M., Wolbers, Judith Olde, Falkenburg, J.H. Frederik, Halkes, Constantijn J.M., Jedema, Inge
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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T Cell Chimerism After T Cell Depleted Allogeneic Stem Cell Transplantation Is Influenced by Immunological Factors Including the Conditioning Regimen, CMV Serostatus and GvHD and Does Significantly Bias Overall Chimerism Status
Harskamp, Jessica C., van der Heiden, Pim L.J., van Egmond, Esther H.M., Veld, Sabrina A.J., Vos, Hans L., Halkes, Constantijn J.M., Falkenburg, J.H. Frederik, Marijt, Erik W.A.
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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