Mechanism of UCH-L5 Activation and Inhibition by DEUBAD Domains in RPN13 and INO80G
Sahtoe, Danny D., van Dijk, Willem J., El Oualid, Farid, Ekkebus, Reggy, Ovaa, Huib, Sixma, Titia K.
Published in Molecular cell (05.03.2015)
Published in Molecular cell (05.03.2015)
Get full text
Journal Article
Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity
Kim, Robbert Q., Geurink, Paul P., Mulder, Monique P. C., Fish, Alexander, Ekkebus, Reggy, El Oualid, Farid, van Dijk, Willem J., van Dalen, Duco, Ovaa, Huib, van Ingen, Hugo, Sixma, Titia K.
Published in Nature communications (16.01.2019)
Published in Nature communications (16.01.2019)
Get full text
Journal Article
BAP1/ASXL1 recruitment and activation for H2A deubiquitination
Sahtoe, Danny D., van Dijk, Willem J., Ekkebus, Reggy, Ovaa, Huib, Sixma, Titia K.
Published in Nature communications (07.01.2016)
Published in Nature communications (07.01.2016)
Get full text
Journal Article
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Mattiroli, Francesca, Vissers, Joseph H.A., van Dijk, Willem J., Ikpa, Pauline, Citterio, Elisabetta, Vermeulen, Wim, Marteijn, Jurgen A., Sixma, Titia K.
Published in Cell (14.09.2012)
Published in Cell (14.09.2012)
Get full text
Journal Article
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
Smit, Judith J, Monteferrario, Davide, Noordermeer, Sylvie M, van Dijk, Willem J, van der Reijden, Bert A, Sixma, Titia K
Published in The EMBO journal (03.10.2012)
Published in The EMBO journal (03.10.2012)
Get full text
Journal Article
Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation
Knipscheer, Puck, van Dijk, Willem J, Olsen, Jesper V, Mann, Matthias, Sixma, Titia K
Published in The EMBO journal (06.06.2007)
Published in The EMBO journal (06.06.2007)
Get full text
Journal Article
Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in AChBP Crystal Structures
Celie, Patrick H.N, van Rossum-Fikkert, Sarah E, van Dijk, Willem J, Brejc, Katjuša, Smit, August B, Sixma, Titia K
Published in Neuron (Cambridge, Mass.) (25.03.2004)
Published in Neuron (Cambridge, Mass.) (25.03.2004)
Get full text
Journal Article
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
Pichler, Andrea, Sixma, Titia K, Knipscheer, Puck, Oberhofer, Edith, van Dijk, Willem J, Körner, Roman, Olsen, Jesper Velgaard, Jentsch, Stefan, Melchior, Frauke
Published in Nature structural & molecular biology (01.03.2005)
Published in Nature structural & molecular biology (01.03.2005)
Get full text
Journal Article
The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types
Faesen, Alex C., Luna-Vargas, Mark P.A., Geurink, Paul P., Clerici, Marcello, Merkx, Remco, van Dijk, Willem J., Hameed, Dharjath S., El Oualid, Farid, Ovaa, Huib, Sixma, Titia K.
Published in Chemistry & biology (23.12.2011)
Published in Chemistry & biology (23.12.2011)
Get full text
Journal Article
Insert L1 is a central hub for allosteric regulation of USP1 activity
Dharadhar, Shreya, van Dijk, Willem J, Scheffers, Serge, Fish, Alexander, Sixma, Titia K
Published in EMBO reports (07.04.2021)
Published in EMBO reports (07.04.2021)
Get full text
Journal Article
Ubc9 Sumoylation Regulates SUMO Target Discrimination
Knipscheer, Puck, Flotho, Annette, Klug, Helene, Olsen, Jesper V., van Dijk, Willem J., Fish, Alexander, Johnson, Erica S., Mann, Matthias, Sixma, Titia K., Pichler, Andrea
Published in Molecular cell (08.08.2008)
Published in Molecular cell (08.08.2008)
Get full text
Journal Article
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases
Luna-Vargas, Mark P.A., Christodoulou, Evangelos, Alfieri, Andrea, van Dijk, Willem J., Stadnik, Magda, Hibbert, Richard G., Sahtoe, Danny D., Clerici, Marcello, Marco, Valeria De, Littler, Dene, Celie, Patrick H.N., Sixma, Titia K., Perrakis, Anastassis
Published in Journal of structural biology (01.08.2011)
Published in Journal of structural biology (01.08.2011)
Get full text
Journal Article
Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain
Luna-Vargas, Mark P A, Faesen, Alex C, van Dijk, Willem J, Rape, Michael, Fish, Alexander, Sixma, Titia K
Published in EMBO reports (01.04.2011)
Published in EMBO reports (01.04.2011)
Get full text
Journal Article