A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium
van der Linden, Franka H., Mahlandt, Eike K., Arts, Janine J. G., Beumer, Joep, Puschhof, Jens, de Man, Saskia M. A., Chertkova, Anna O., Ponsioen, Bas, Clevers, Hans, van Buul, Jaap D., Postma, Marten, Gadella, Theodorus W. J., Goedhart, Joachim
Published in Nature communications (09.12.2021)
Published in Nature communications (09.12.2021)
Get full text
Journal Article
The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models
Klems, Alina, van Rijssel, Jos, Ramms, Anne S., Wild, Raphael, Hammer, Julia, Merkel, Melanie, Derenbach, Laura, Préau, Laetitia, Hinkel, Rabea, Suarez-Martinez, Irina, Schulte-Merker, Stefan, Vidal, Ramon, Sauer, Sascha, Kivelä, Riikka, Alitalo, Kari, Kupatt, Christian, van Buul, Jaap D., le Noble, Ferdinand
Published in Nature communications (21.10.2020)
Published in Nature communications (21.10.2020)
Get full text
Journal Article
Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans
van der Valk, Fleur M, Bekkering, Siroon, Kroon, Jeffrey, Yeang, Calvin, Van den Bossche, Jan, van Buul, Jaap D, Ravandi, Amir, Nederveen, Aart J, Verberne, Hein J, Scipione, Corey, Nieuwdorp, Max, Joosten, Leo A.B, Netea, Mihai G, Koschinsky, Marlys L, Witztum, Joseph L, Tsimikas, Sotirios, Riksen, Niels P, Stroes, Erik S.G
Published in Circulation (New York, N.Y.) (23.08.2016)
Published in Circulation (New York, N.Y.) (23.08.2016)
Get full text
Journal Article
Opto-RhoGEFs, an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength
Mahlandt, Eike K, Palacios Martínez, Sebastián, Arts, Janine J G, Tol, Simon, van Buul, Jaap D, Goedhart, Joachim
Published in eLife (14.07.2023)
Published in eLife (14.07.2023)
Get full text
Journal Article
The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis
Kempers, Lanette, Wakayama, Yuki, van der Bijl, Ivo, Furumaya, Charita, De Cuyper, Iris M., Jongejan, Aldo, Kat, Marije, van Stalborch, Anne-Marieke D., van Boxtel, Antonius L., Hubert, Marvin, Geerts, Dirk, van Buul, Jaap D., de Korte, Dirk, Herzog, Wiebke, Margadant, Coert
Published in Angiogenesis (London) (01.08.2021)
Published in Angiogenesis (London) (01.08.2021)
Get full text
Journal Article
Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency
Block, Jana, Rashkova, Christina, Castanon, Irinka, Zoghi, Samaneh, Platon, Jessica, Ardy, Rico C., Fujiwara, Mitsuhiro, Chaves, Beatriz, Schoppmeyer, Rouven, van der Made, Caspar I., Jimenez Heredia, Raul, Harms, Frederike L., Alavi, Samin, Alsina, Laia, Sanchez Moreno, Paula, Ávila Polo, Rainiero, Cabrera-Pérez, Rocío, Kostel Bal, Sevgi, Pfajfer, Laurène, Ransmayr, Bernhard, Mautner, Anna-Katharina, Kondo, Ryohei, Tinnacher, Anna, Caldera, Michael, Schuster, Michael, Domínguez Conde, Cecilia, Platzer, René, Salzer, Elisabeth, Boyer, Thomas, Brunner, Han G., Nooitgedagt-Frons, Judith E., Iglesias, Estíbaliz, Deyà-Martinez, Angela, Camacho-Lovillo, Marisol, Menche, Jörg, Bock, Christoph, Huppa, Johannes B., Pickl, Winfried F., Distel, Martin, Yoder, Jeffrey A., Traver, David, Engelhardt, Karin R., Linden, Tobias, Kager, Leo, Hannich, J. Thomas, Hoischen, Alexander, Hambleton, Sophie, Illsinger, Sabine, Da Costa, Lydie, Kutsche, Kerstin, Chavoshzadeh, Zahra, van Buul, Jaap D., Antón, Jordi, Calzada-Hernández, Joan, Neth, Olaf, Viaud, Julien, Nishikimi, Akihiko, Dupré, Loïc, Boztug, Kaan
Published in The New England journal of medicine (10.08.2023)
Published in The New England journal of medicine (10.08.2023)
Get full text
Journal Article
Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking
Daniel, Anna E, Timmerman, Ilse, Kovacevic, Igor, Hordijk, Peter L, Adriaanse, Luc, Paatero, Ilkka, Belting, Heinz-Georg, van Buul, Jaap D
Published in PloS one (29.12.2015)
Published in PloS one (29.12.2015)
Get full text
Journal Article
Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium
Rademakers, Timo, Goedhart, Marieke, Hoogenboezem, Mark, García Ponce, Alexander, van Rijssel, Jos, Samus, Maryna, Schnoor, Michael, Butz, Stefan, Huveneers, Stephan, Vestweber, Dietmar, Nolte, Martijn A, Voermans, Carlijn, van Buul, Jaap D
Published in Haematologica (Roma) (23.01.2020)
Published in Haematologica (Roma) (23.01.2020)
Get full text
Journal Article
F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling
Heemskerk, Niels, Schimmel, Lilian, Oort, Chantal, van Rijssel, Jos, Yin, Taofei, Ma, Bin, van Unen, Jakobus, Pitter, Bettina, Huveneers, Stephan, Goedhart, Joachim, Wu, Yi, Montanez, Eloi, Woodfin, Abigail, van Buul, Jaap D.
Published in Nature communications (27.01.2016)
Published in Nature communications (27.01.2016)
Get full text
Journal Article
Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration
Arts, Janine JG, Mahlandt, Eike K, Grönloh, Max LB, Schimmel, Lilian, Noordstra, Ivar, Gordon, Emma, van Steen, Abraham CI, Tol, Simon, Walzog, Barbara, van Rijssel, Jos, Nolte, Martijn A, Postma, Marten, Khuon, Satya, Heddleston, John M, Wait, Eric, Chew, Teng Leong, Winter, Mark, Montanez, Eloi, Goedhart, Joachim, van Buul, Jaap D
Published in eLife (25.08.2021)
Published in eLife (25.08.2021)
Get full text
Journal Article
Inflammation-Sensitive Myosin-X Functionally Supports Leukocyte Extravasation by Cdc42-Mediated ICAM-1-Rich Endothelial Filopodia Formation
Kroon, Jeffrey, Schaefer, Antje, van Rijssel, Jos, Hoogenboezem, Mark, van Alphen, Floris, Hordijk, Peter, Stroes, Erik S G, Strömblad, Staffan, van Rheenen, Jacco, van Buul, Jaap D
Published in The Journal of immunology (1950) (01.03.2018)
Published in The Journal of immunology (1950) (01.03.2018)
Get full text
Journal Article
A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1
Timmerman, Ilse, Heemskerk, Niels, Kroon, Jeffrey, Schaefer, Antje, van Rijssel, Jos, Hoogenboezem, Mark, van Unen, Jakobus, Goedhart, Joachim, Gadella, Jr, Theodorus W J, Yin, Taofei, Wu, Yi, Huveneers, Stephan, van Buul, Jaap D
Published in Journal of cell science (15.08.2015)
Published in Journal of cell science (15.08.2015)
Get full text
Journal Article
Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
Park, Hongryeol, Song, Jian, Jeong, Hyun-Woo, Grönloh, Max L. B., Koh, Bong Ihn, Bovay, Esther, Kim, Kee-Pyo, Klotz, Luisa, Thistlethwaite, Patricia A., van Buul, Jaap D., Sorokin, Lydia, Adams, Ralf H.
Published in Nature communications (25.07.2024)
Published in Nature communications (25.07.2024)
Get full text
Journal Article
Endothelial Barrier Function and Leukocyte Transmigration in Atherosclerosis
Sluiter, Thijs J, van Buul, Jaap D, Huveneers, Stephan, Quax, Paul H A, de Vries, Margreet R
Published in Biomedicines (24.03.2021)
Published in Biomedicines (24.03.2021)
Get full text
Journal Article
Actin-binding proteins differentially regulate endothelial cell stiffness, ICAM-1 function and neutrophil transmigration
Schaefer, Antje, Te Riet, Joost, Ritz, Katja, Hoogenboezem, Mark, Anthony, Eloise C, Mul, Frederik P J, de Vries, Carlie J, Daemen, Mat J, Figdor, Carl G, van Buul, Jaap D, Hordijk, Peter L
Published in Journal of cell science (15.10.2014)
Published in Journal of cell science (15.10.2014)
Get full text
Journal Article
Diabetes Mellitus Induces Bone Marrow Microangiopathy
Oikawa, Atsuhiko, Siragusa, Mauro, Quaini, Federico, Mangialardi, Giuseppe, Katare, Rajesh G, Caporali, Andrea, van Buul, Jaap D, van Alphen, Floris P.J, Graiani, Gallia, Spinetti, Gaia, Kraenkel, Nicolle, Prezioso, Lucia, Emanueli, Costanza, Madeddu, Paolo
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
Get full text
Journal Article