Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer
de Streel, Grégoire, Bertrand, Charlotte, Chalon, Nicolas, Liénart, Stéphanie, Bricard, Orian, Lecomte, Sara, Devreux, Julien, Gaignage, Mélanie, De Boeck, Gitte, Mariën, Lore, Van De Walle, Inge, van der Woning, Bas, Saunders, Michael, de Haard, Hans, Vermeersch, Elien, Maes, Wim, Deckmyn, Hans, Coulie, Pierre G., van Baren, Nicolas, Lucas, Sophie
Published in Nature communications (11.09.2020)
Published in Nature communications (11.09.2020)
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Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Johansson, Peter A., Brooks, Kelly, Newell, Felicity, Palmer, Jane M., Wilmott, James S., Pritchard, Antonia L., Broit, Natasa, Wood, Scott, Carlino, Matteo S., Leonard, Conrad, Koufariotis, Lambros T., Nathan, Vaishnavi, Beasley, Aaron B., Howlie, Madeleine, Dawson, Rebecca, Rizos, Helen, Schmidt, Chris W., Long, Georgina V., Hamilton, Hayley, Kiilgaard, Jens F., Isaacs, Timothy, Gray, Elin S., Rolfe, Olivia J., Park, John J., Stark, Andrew, Mann, Graham J., Scolyer, Richard A., Pearson, John V., van Baren, Nicolas, Waddell, Nicola, Wadt, Karin W., McGrath, Lindsay A., Warrier, Sunil K., Glasson, William, Hayward, Nicholas K.
Published in Nature communications (15.05.2020)
Published in Nature communications (15.05.2020)
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Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells
Tilman, Gaëlle, Mattiussi, Marina, Brasseur, Francis, van Baren, Nicolas, Decottignies, Anabelle
Published in Molecular cancer (17.12.2007)
Published in Molecular cancer (17.12.2007)
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Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
Zhu, Jingjing, Powis de Tenbossche, Céline G., Cané, Stefania, Colau, Didier, van Baren, Nicolas, Lurquin, Christophe, Schmitt-Verhulst, Anne-Marie, Liljeström, Peter, Uyttenhove, Catherine, Van den Eynde, Benoit J.
Published in Nature communications (10.11.2017)
Published in Nature communications (10.11.2017)
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Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy
Shi, Hubing, Hugo, Willy, Kong, Xiangju, Hong, Aayoung, Koya, Richard C, Moriceau, Gatien, Chodon, Thinle, Guo, Rongqing, Johnson, Douglas B, Dahlman, Kimberly B, Kelley, Mark C, Kefford, Richard F, Chmielowski, Bartosz, Glaspy, John A, Sosman, Jeffrey A, van Baren, Nicolas, Long, Georgina V, Ribas, Antoni, Lo, Roger S
Published in Cancer discovery (01.01.2014)
Published in Cancer discovery (01.01.2014)
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Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
CIPPONI, Arcadi, MERCIER, Marjorie, SEREMET, Teofila, BAURAIN, Jean-François, THEATE, Ivan, VAN DEN OORD, Joost, STAS, Marguerite, BOON, Thierry, COULIE, Pierre G, VAN BAREN, Nicolas
Published in Cancer research (Chicago, Ill.) (15.08.2012)
Published in Cancer research (Chicago, Ill.) (15.08.2012)
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Extensive profiling of the expression of the indoleamine 2,3-dioxygenase 1 protein in normal and tumoral human tissues
Théate, Ivan, van Baren, Nicolas, Pilotte, Luc, Moulin, Pierre, Larrieu, Pierre, Renauld, Jean-Christophe, Hervé, Caroline, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Sempoux, Christine, Van den Eynde, Benoît J
Published in Cancer immunology research (01.02.2015)
Published in Cancer immunology research (01.02.2015)
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Antigen Spreading Contributes to MAGE Vaccination-Induced Regression of Melanoma Metastases
CORBIERE, Véronique, CHAPIRO, Jacques, STROOBANT, Vincent, WENBIN MA, LURQUIN, Christophe, LETHE, Bernard, VAN BAREN, Nicolas, VAN DEN EYNDE, Benoît J, BOON, Thierry, COULIE, Pierre G
Published in Cancer research (Chicago, Ill.) (15.02.2011)
Published in Cancer research (Chicago, Ill.) (15.02.2011)
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Spatial Distribution of Non-Immune Cells Expressing Glycoprotein A Repetitions Predominant in Human and Murine Metastatic Lymph Nodes
Rouaud, Loïc, Baudin, Louis, Gautier-Isola, Marine, Van Meerbeeck, Pierre, Feyereisen, Emilie, Blacher, Silvia, van Baren, Nicolas, Kridelka, Frédéric, Lucas, Sophie, Noel, Agnes
Published in Cancers (28.11.2023)
Published in Cancers (28.11.2023)
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Highly Aggressive Metastatic Melanoma Cells Unable to Maintain Telomere Length
Viceconte, Nikenza, Dheur, Marie-Sophie, Majerova, Eva, Pierreux, Christophe E., Baurain, Jean-François, van Baren, Nicolas, Decottignies, Anabelle
Published in Cell reports (Cambridge) (20.06.2017)
Published in Cell reports (Cambridge) (20.06.2017)
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Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers
Hoffmann, Delia, Dvorakova, Tereza, Stroobant, Vincent, Bouzin, Caroline, Daumerie, Aurélie, Solvay, Marie, Klaessens, Simon, Letellier, Marie-Claire, Renauld, Jean-Christophe, van Baren, Nicolas, Lelotte, Julie, Marbaix, Etienne, Van den Eynde, Benoit J
Published in Cancer immunology research (01.01.2020)
Published in Cancer immunology research (01.01.2020)
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Combined Blockade of GARP:TGF-β1 and PD-1 Increases Infiltration of T Cells and Density of Pericyte-Covered GARP + Blood Vessels in Mouse MC38 Tumors
Bertrand, Charlotte, Van Meerbeeck, Pierre, de Streel, Grégoire, Vaherto-Bleeckx, Noora, Benhaddi, Fatima, Rouaud, Loïc, Noël, Agnès, Coulie, Pierre G, van Baren, Nicolas, Lucas, Sophie
Published in Frontiers in immunology (27.07.2021)
Published in Frontiers in immunology (27.07.2021)
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DNA methylation profiling reveals a predominant immune component in breast cancers
Dedeurwaerder, Sarah, Desmedt, Christine, Calonne, Emilie, Singhal, Sandeep K., Haibe‐Kains, Benjamin, Defrance, Matthieu, Michiels, Stefan, Volkmar, Michael, Deplus, Rachel, Luciani, Judith, Lallemand, Françoise, Larsimont, Denis, Toussaint, Jérôme, Haussy, Sandy, Rothé, Françoise, Rouas, Ghizlane, Metzger, Otto, Majjaj, Samira, Saini, Kamal, Putmans, Pascale, Hames, Gérald, van Baren, Nicolas, Coulie, Pierre G., Piccart, Martine, Sotiriou, Christos, Fuks, François
Published in EMBO molecular medicine (01.12.2011)
Published in EMBO molecular medicine (01.12.2011)
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Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?
Cipponi, Arcadi, Wieers, Grégoire, van Baren, Nicolas, Coulie, Pierre G.
Published in Cancer Immunology, Immunotherapy (01.08.2011)
Published in Cancer Immunology, Immunotherapy (01.08.2011)
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Demethylation of the FOXP3 gene in human melanoma cells precludes the use of this epigenetic mark for quantification of Tregs in unseparated melanoma samples
Lucas, Sophie, van Baren, Nicolas, de Smet, Charles, Coulie, Pierre G.
Published in International journal of cancer (15.04.2012)
Published in International journal of cancer (15.04.2012)
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Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAGE Antigen
Lonchay, Christophe, van der Bruggen, Pierre, Connerotte, Thierry, Hanagiri, Takeshi, Coulie, Pierre, Colau, Didier, Lucas, Sophie, Van Pel, Aline, Thielemans, Kris, van Baren, Nicolas, Boon, Thierry
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2004)
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Tumoral and Immunologic Response After Vaccination of Melanoma Patients With an ALVAC Virus Encoding MAGE Antigens Recognized by T Cells
VAN BAREN, Nicolas, BONNET, Marie-Claude, ESCUDIER, Bernard, NEGRIER, Sylvie, DIETRICH, Pierre-Yves, MARANINCHI, Dominique, OSANTO, Susanne, MEYER, Ralf G, RITTER, Gerd, MOINGEON, Philippe, TARTAGLIA, Jim, VAN DER BRUGGEN, Pierre, DRENO, Brigitte, COULIE, Pierre G, BOON, Thierry, KHAMMARI, Amir, DORVAL, Thierry, PIPERNO-NEUMANN, Sophie, LIENARD, Danielle, SPEISER, Daniel, MARCHAND, Marie, BRICHARD, Vincent G
Published in Journal of clinical oncology (10.12.2005)
Published in Journal of clinical oncology (10.12.2005)
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Local immunostimulation leading to rejection of accepted male skin grafts by female mice as a model for cancer immunotherapy
Bourdeaux, Christophe, Lurquin, Christophe, Jacquemart, Isabelle, Lethé, Bernard, Brasseur, Francis, van Baren, Nicolas, Baurain, Jean-François, Dyson, Julian, Van Snick, Jacques, Uyttenhove, Catherine, Boon, Thierry
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2014)
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