Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange
van der Neut Kolfschoten, Marijn, Schuurman, Janine, Losen, Mario, Bleeker, Wim K., Martínez-Martínez, Pilar, Vermeulen, Ellen, Bleker, Tamara H. den, Wiegman, Luus, Vink, Tom, Aarden, Lucien A., De Baets, Marc H., van de Winkel, Jan G. J., Aalberse, Rob C., Parren, Paul W. H. I.
Published in Science (American Association for the Advancement of Science) (14.09.2007)
Published in Science (American Association for the Advancement of Science) (14.09.2007)
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Journal Article
Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies
DECHANT, Michael, WEISNER, Wencke, VALERIUS, Thomas, BERGER, Sven, PEIPP, Matthias, BEYER, Thomas, SCHNEIDER-MERCK, Tanja, LAMMERTS VAN BUEREN, Jeroen J, BLEEKER, Wim K, PARREN, Paul W. H. I, VAN DE WINKEL, Jan G. J
Published in Cancer research (Chicago, Ill.) (01.07.2008)
Published in Cancer research (Chicago, Ill.) (01.07.2008)
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Journal Article
Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry
Rose, Rebecca J., Labrijn, Aran F., van den Bremer, Ewald T.J., Loverix, Stefan, Lasters, Ignace, van Berkel, Patrick H.C., van de Winkel, Jan G.J., Schuurman, Janine, Parren, Paul W.H.I., Heck, Albert J.R.
Published in Structure (London) (07.09.2011)
Published in Structure (London) (07.09.2011)
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Journal Article
Effect of target dynamics on pharmacokinetics of a novel therapeutic antibody against the epidermal growth factor receptor : Implications for the mechanisms of action
LAMMERTS VAN BUEREN, Jeroen J, BLEEKER, Wim K, BOGH, Henrik O, HOUTKAMP, Mischa, SCHUURMAN, Janine, VAN DE WINKEL, Jan G. J, PARREN, Paul W. H. I
Published in Cancer research (Chicago, Ill.) (01.08.2006)
Published in Cancer research (Chicago, Ill.) (01.08.2006)
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Journal Article
Oncogenic KRAS Impairs EGFR Antibodies' Efficiency by C/EBPβ-Dependent Suppression of EGFR Expression
Derer, Stefanie, Berger, Sven, Schlaeth, Martin, Schneider-Merck, Tanja, Klausz, Katja, Lohse, Stefan, Overdijk, Marije B, Dechant, Michael, Kellner, Christian, Nagelmeier, Iris, Scheel, Andreas H, Lammerts van Bueren, Jeroen J, van de Winkel, Jan G.J, Parren, Paul W.H.I, Peipp, Matthias, Valerius, Thomas
Published in Neoplasia (New York, N.Y.) (01.03.2012)
Published in Neoplasia (New York, N.Y.) (01.03.2012)
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Journal Article
Human antibodies as next generation therapeutics
van Dijk, Marc A, van de Winkel, Jan G.J
Published in Current Opinion in Chemical Biology (01.08.2001)
Published in Current Opinion in Chemical Biology (01.08.2001)
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Book Review
Journal Article
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling
de Haij, Simone, Jansen, J H Marco, Boross, Peter, Beurskens, Frank J, Bakema, Jantine E, Bos, Desiree L, Martens, Anton, Verbeek, J Sjef, Parren, Paul W H I, van de Winkel, Jan G J, Leusen, Jeanette H W
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Mechanisms of G-CSF- or GM-CSF-stimulated tumor cell killing by Fc receptor-directed bispecific antibodies
Stockmeyer, Bernhard, Elsässer, David, Dechant, Michael, Repp, Roland, Gramatzki, Martin, Glennie, Martin J, van de Winkel, Jan G.J, Valerius, Thomas
Published in Journal of immunological methods (01.02.2001)
Published in Journal of immunological methods (01.02.2001)
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Journal Article
Ganglioside-specific IgG and IgA recruit leukocyte effector functions in Guillain–Barré syndrome
van Sorge, Nina M, Yuki, Nobuhiro, Koga, Michiaki, Susuki, Keiichiro, Jansen, Marc D, van Kooten, Cees, Wokke, John H.J, van de Winkel, Jan G.J, van der Pol, W-Ludo, van den Berg, Leonard H
Published in Journal of neuroimmunology (01.01.2007)
Published in Journal of neuroimmunology (01.01.2007)
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Journal Article
The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden
BOROSS, Peter, MARCO JANSEN, J. H, LEUSEN, Jeanette H. W, DE HAIJ, Simone, BEURSKENS, Frank J, VAN DER POEL, Cees E, BEVAART, Lisette, NEDEREND, Maaike, GOLAY, Josée, VAN DE WINKEL, Jan G. J, PARREN, Paul W. H. I
Published in Haematologica (Roma) (01.12.2011)
Published in Haematologica (Roma) (01.12.2011)
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Journal Article
IgA and the IgA Fc receptor
van Egmond, Marjolein, Damen, Cora A, van Spriel, Annemiek B, Vidarsson, Gestur, van Garderen, Evert, van de Winkel, Jan G.J
Published in Trends in Immunology (01.04.2001)
Published in Trends in Immunology (01.04.2001)
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Book Review
Journal Article
Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
Villadsen, Louise S, Schuurman, Janine, Beurskens, Frank, Dam, Tomas N, Dagnaes-Hansen, Frederik, Skov, Lone, Rygaard, Jorgen, Voorhorst-Ogink, Marleen M, Gerritsen, Arnout F, van Dijk, Marc A, Parren, Paul W H I, Baadsgaard, Ole, van de Winkel, Jan G J
Published in The Journal of clinical investigation (01.11.2003)
Published in The Journal of clinical investigation (01.11.2003)
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Journal Article
Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC
Repp, Roland, Kellner, Christian, Muskulus, Anja, Staudinger, Matthias, Mohseni Nodehi, Sahar, Glorius, Pia, Akramiene, Dalia, Dechant, Michael, Fey, Georg H., van Berkel, Patrick H.C., van de Winkel, Jan G.J., Parren, Paul W.H.I., Valerius, Thomas, Gramatzki, Martin, Peipp, Matthias
Published in Journal of immunological methods (28.10.2011)
Published in Journal of immunological methods (28.10.2011)
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Journal Article
Inflammation in autoimmunity: receptors for IgG revisited
Dijstelbloem, Hilde M, Kallenberg, Cees G.M, van de Winkel, Jan G.J
Published in Trends in Immunology (01.09.2001)
Published in Trends in Immunology (01.09.2001)
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Book Review
Journal Article
Rapid production of recombinant human IgG With improved ADCC effector function in a transient expression system
van Berkel, Patrick H.C, Gerritsen, Jolanda, van Voskuilen, Edwin, Perdok, Gerrard, Vink, Tom, van de Winkel, Jan G.J, Parren, Paul W.H.I
Published in Biotechnology and bioengineering (01.02.2010)
Published in Biotechnology and bioengineering (01.02.2010)
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Journal Article
FcαRI-positive liver Kupffer cells: Reappraisal of the function of immunoglobulin A in immunity
van de Winkel, Jan G.J, van Egmond, Marjolein, van Garderen, Evert, van Spriel, Annemiek B, Damen, Cora A, van Amersfoort, Edwin S, van Zandbergen, Ger, van Hattum, Jan, Kuiper, Johan
Published in Nature medicine (01.06.2000)
Published in Nature medicine (01.06.2000)
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Journal Article
antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility
Lammerts van Bueren, Jeroen J, Bleeker, Wim K, Brännström, Annika, von Euler, Anne, Jansson, Magnus, Peipp, Matthias, Schneider-Merck, Tanja, Valerius, Thomas, van de Winkel, Jan G.J, Parren, Paul W.H.I
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
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Journal Article
Complement‐mediated tumor‐specific cell lysis by antibody combinations targeting epidermal growth factor receptor (EGFR) and its variant III (EGFRvIII)
Klausz, Katja, Berger, Sven, Lammerts van Bueren, Jeroen J., Derer, Stefanie, Lohse, Stefan, Dechant, Michael, van de Winkel, Jan G. J., Peipp, Matthias, Parren, Paul W. H. I., Valerius, Thomas
Published in Cancer science (01.10.2011)
Published in Cancer science (01.10.2011)
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