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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models
Linnekamp, Janneke F., Hooff, Sander R. van, Prasetyanti, Pramudita R., Kandimalla, Raju, Buikhuisen, Joyce Y., Fessler, Evelyn, Ramesh, Prashanthi, Lee, Kelly A. S. T., Bochove, Grehor G. W., de Jong, Johan H., Cameron, Kate, Leersum, Ronald van, Rodermond, Hans M., Franitza, Marek, Nürnberg, Peter, Mangiapane, Laura R., Wang, Xin, Clevers, Hans, Vermeulen, Louis, Stassi, Giorgio, Medema, Jan Paul
Published in Cell death and differentiation (01.03.2018)
Published in Cell death and differentiation (01.03.2018)
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BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer
Ramesh, Prashanthi, Lannagan, Tamsin R. M., Jackstadt, Rene, Atencia Taboada, Lidia, Lansu, Nico, Wirapati, Pratyaksha, van Hooff, Sander R., Dekker, Danielle, Pritchard, Jessica, Kirov, Aleksandar B., van Neerven, Sanne M., Tejpar, Sabine, Kops, Geert J. P. L., Sansom, Owen J., Medema, Jan Paul
Published in Cell death and differentiation (01.12.2021)
Published in Cell death and differentiation (01.12.2021)
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Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems
Dijk, Frederike, Veenstra, Veronique L., Soer, Eline C., Dings, Mark P. G., Zhao, Lan, Halfwerk, Johannes B., Hooijer, Gerrit K., Damhofer, Helene, Marzano, Marco, Steins, Anne, Waasdorp, Cynthia, Busch, Olivier R., Besselink, Marc G., Tol, Johanna A., Welling, Lieke, van Rijssen, Lennart B., Klompmaker, Sjors, Wilmink, Hanneke W., van Laarhoven, Hanneke W., Medema, Jan Paul, Vermeulen, Louis, van Hooff , Sander R., Koster, Jan, Verheij, Joanne, van de Vijver, Marc J., Wang, Xin, Bijlsma, Maarten F.
Published in Scientific reports (15.01.2020)
Published in Scientific reports (15.01.2020)
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Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma
Keller, Kaylee M., Eleveld, Thomas F., Schild, Linda, van den Handel, Kim, van den Boogaard, Marlinde, Amo-Addae, Vicky, Eising, Selma, Ober, Kimberley, Koopmans, Bianca, Looijenga, Leendert, Tytgat, Godelieve A.M., Ylstra, Bauke, Molenaar, Jan J., Dolman, M. Emmy M., van Hooff, Sander R.
Published in Frontiers in oncology (27.09.2022)
Published in Frontiers in oncology (27.09.2022)
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Novel diagnostic modalities for assessment of the clinically node-negative neck in oral squamous-cell carcinoma
Leusink, Frank KJ, van Es, Robert JJ, de Bree, Remco, de Jong, Robert J Baatenburg, van Hooff, Sander R, Holstege, Frank CP, Slootweg, Piet J, Brakenhoff, Ruud H, Takes, Robert P
Published in The lancet oncology (01.12.2012)
Published in The lancet oncology (01.12.2012)
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Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes
Cobos, Francisco Avila, Panah, Mohammad Javad Najaf, Epps, Jessica, Long, Xiaochen, Man, Tsz-Kwong, Chiu, Hua-Sheng, Chomsky, Elad, Kiner, Evgeny, Krueger, Michael J., di Bernardo, Diego, Voloch, Luis, Molenaar, Jan, van Hooff, Sander R., Westermann, Frank, Jansky, Selina, Redell, Michele L., Mestdagh, Pieter, Sumazin, Pavel
Published in Genome Biology (01.08.2023)
Published in Genome Biology (01.08.2023)
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An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF
Koot, Yvonne E. M., van Hooff, Sander R., Boomsma, Carolien M., van Leenen, Dik, Groot Koerkamp, Marian J. A., Goddijn, Mariëtte, Eijkemans, Marinus J. C., Fauser, Bart C. J. M., Holstege, Frank C. P., Macklon, Nick S.
Published in Scientific reports (22.01.2016)
Published in Scientific reports (22.01.2016)
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TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype
Fessler, Evelyn, Drost, Jarno, van Hooff, Sander R, Linnekamp, Janneke F, Wang, Xin, Jansen, Marnix, De Sousa E Melo, Felipe, Prasetyanti, Pramudita R, IJspeert, Joep EG, Franitza, Marek, Nürnberg, Peter, van Noesel, Carel JM, Dekker, Evelien, Vermeulen, Louis, Clevers, Hans, Medema, Jan Paul
Published in EMBO molecular medicine (01.07.2016)
Published in EMBO molecular medicine (01.07.2016)
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Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
Calandrini, Camilla, van Hooff, Sander R., Paassen, Irene, Ayyildiz, Dilara, Derakhshan, Sepide, Dolman, M. Emmy M., Langenberg, Karin P.S., van de Ven, Marieke, de Heus, Cecilia, Liv, Nalan, Kool, Marcel, de Krijger, Ronald R., Tytgat, Godelieve A.M., van den Heuvel-Eibrink, Marry M., Molenaar, Jan J., Drost, Jarno
Published in Cell reports (Cambridge) (24.08.2021)
Published in Cell reports (Cambridge) (24.08.2021)
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Two opposing gene expression patterns within ATRX aberrant neuroblastoma
van Gerven, Michael R., Schild, Linda, van Arkel, Jennemiek, Koopmans, Bianca, Broeils, Luuk A., Meijs, Loes A. M., van Oosterhout, Romy, van Noesel, Max M., Koster, Jan, van Hooff, Sander R., Molenaar, Jan J., van den Boogaard, Marlinde L.
Published in PloS one (04.08.2023)
Published in PloS one (04.08.2023)
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The potential of PARP as a therapeutic target across pediatric solid malignancies
Keller, Kaylee M., Koetsier, Joost, Schild, Linda, Amo-Addae, Vicky, Eising, Selma, van den Handel, Kim, Ober, Kimberley, Koopmans, Bianca, Essing, Anke, van den Boogaard, Marlinde L., Langenberg, Karin P. S., Jäger, Natalie, Kool, Marcel, Pfister, Stefan, Dolman, M. Emmy M., Molenaar, Jan J., van Hooff, Sander R.
Published in BMC cancer (05.04.2023)
Published in BMC cancer (05.04.2023)
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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models
Linnekamp, Janneke F., Hooff, Sander R. van, Prasetyanti, Pramudita R., Kandimalla, Raju, Buikhuisen, Joyce Y., Fessler, Evelyn, Ramesh, Prashanthi, Lee, Kelly A. S. T., Bochove, Grehor G. W., de Jong, Johan H., Cameron, Kate, Leersum, Ronald van, Rodermond, Hans M., Franitza, Marek, Nürnberg, Peter, Mangiapane, Laura R., Wang, Xin, Clevers, Hans, Vermeulen, Louis, Stassi, Giorgio, Medema, Jan Paul
Published in Cell death and differentiation (05.01.2018)
Published in Cell death and differentiation (05.01.2018)
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A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues
de Back, Tim R, Wu, Tan, Schafrat, Pascale JM, ten Hoorn, Sanne, Tan, Miaomiao, He, Lingli, van Hooff, Sander R, Koster, Jan, Nijman, Lisanne E, Vink, Geraldine R, Beumer, Inès J, Elbers, Clara C, Lenos, Kristiaan J, Sommeijer, Dirkje W, Wang, Xin, Vermeulen, Louis
Published in Life science alliance (01.08.2024)
Published in Life science alliance (01.08.2024)
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PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells
Steller, Ernst J.A., Raats, Danielle A., Koster, Jan, Rutten, Bert, Govaert, Klaas M., Emmink, Benjamin L., Snoeren, Nikol, van Hooff, Sander R., Holstege, Frank C.P., Maas, Coen, Borel, Rinkes Inne H.M., Kranenburg, Onno
Published in Neoplasia (New York, N.Y.) (01.02.2013)
Published in Neoplasia (New York, N.Y.) (01.02.2013)
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Exploring Gene Expression Signatures for Predicting Disease Free Survival after Resection of Colorectal Cancer Liver Metastases
Snoeren, Nikol, van Hooff, Sander R., Adam, Rene, van Hillegersberg, Richard, Voest, Emile E., Guettier, Catherine, van Diest, Paul J., Nijkamp, Maarten W., Brok, Mariel O., van Leenen, Dik, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Borel Rinkes, Inne H. M.
Published in PloS one (21.11.2012)
Published in PloS one (21.11.2012)
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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
Leach, Joshua D. G., Vlahov, Nikola, Tsantoulis, Petros, Ridgway, Rachel A., Flanagan, Dustin J., Gilroy, Kathryn, Sphyris, Nathalie, Vázquez, Ester G., Vincent, David F., Faller, William J., Hodder, Michael C., Raven, Alexander, Fey, Sigrid, Najumudeen, Arafath K., Strathdee, Douglas, Nixon, Colin, Hughes, Mark, Clark, William, Shaw, Robin, van Hooff, Sander R., Huels, David J., Medema, Jan Paul, Barry, Simon T., Frame, Margaret C., Unciti-Broceta, Asier, Leedham, Simon J., Inman, Gareth J., Jackstadt, Rene, Thompson, Barry J., Campbell, Andrew D., Tejpar, Sabine, Sansom, Owen J.
Published in Nature communications (08.06.2021)
Published in Nature communications (08.06.2021)
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Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors
Kemmeren, Patrick, Sameith, Katrin, van de Pasch, Loes A.L., Benschop, Joris J., Lenstra, Tineke L., Margaritis, Thanasis, O’Duibhir, Eoghan, Apweiler, Eva, van Wageningen, Sake, Ko, Cheuk W., van Heesch, Sebastiaan, Kashani, Mehdi M., Ampatziadis-Michailidis, Giannis, Brok, Mariel O., Brabers, Nathalie A.C.H., Miles, Anthony J., Bouwmeester, Diane, van Hooff, Sander R., van Bakel, Harm, Sluiters, Erik, Bakker, Linda V., Snel, Berend, Lijnzaad, Philip, van Leenen, Dik, Groot Koerkamp, Marian J.A., Holstege, Frank C.P.
Published in Cell (24.04.2014)
Published in Cell (24.04.2014)
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Transcriptomic subtyping of gastrointestinal malignancies
de Back, Tim R, van Hooff, Sander R, Sommeijer, Dirkje W, Vermeulen, Louis
Published in Trends in cancer (01.09.2024)
Published in Trends in cancer (01.09.2024)
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Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models
Prasetyanti, Pramudita R., Hooff, Sander R., Herwaarden, Tessa, Vries, Nathalie, Kalloe, Kieshen, Rodermond, Hans, Leersum, Ronald, Jong, Joan H., Franitza, Marek, Nürnberg, Peter, Todaro, Matilde, Stassi, Giorgio, Medema, Jan Paul
Published in International journal of cancer (15.01.2019)
Published in International journal of cancer (15.01.2019)
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