Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
Stockwell, Simon R, Platt, Georgina, Barrie, S Elaine, Zoumpoulidou, Georgia, Te Poele, Robert H, Aherne, G Wynne, Wilson, Stuart C, Sheldrake, Peter, McDonald, Edward, Venet, Mathilde, Soudy, Christelle, Elustondo, Frédéric, Rigoreau, Laurent, Blagg, Julian, Workman, Paul, Garrett, Michelle D, Mittnacht, Sibylle
Published in PloS one (12.01.2012)
Published in PloS one (12.01.2012)
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The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis
Whittaker, Steven R., te Poele, Robert H., Chan, Florence, Linardopoulos, Spiros, Walton, Michael I., Garrett, Michelle D., Workman, Paul
Published in Cell cycle (Georgetown, Tex.) (15.12.2007)
Published in Cell cycle (Georgetown, Tex.) (15.12.2007)
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DNA damage is able to induce senescence in tumor cells in vitro and in vivo
TE POELE, Robert H, OKOROKOV, Andrei L, JARDINE, Lesley, CUMMINGS, Jeffrey, JOEL, Simon P
Published in Cancer research (Chicago, Ill.) (15.03.2002)
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Published in Cancer research (Chicago, Ill.) (15.03.2002)
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AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
YAP, Timothy A, WALTON, Mike I, HEINZMANN, Kathrin, JONES, Paul S, FELTELL, Ruth E, REULE, Matthias, WOODHEAD, Steven J, DAVIES, Thomas G, LYONS, John F, RAYNAUD, Florence I, ECCLES, Suzanne A, WORKMAN, Paul, GRIMSHAW, Kyla M, THOMPSON, Neil T, GARRETT, Michelle D, TE POELE, Robert H, EVE, Paul D, VALENTI, Melanie R, DE HAVEN BRANDON, Alexis K, MARTINS, Vanessa, ZETTERLUND, Anna, HEATON, Simon P
Published in Clinical cancer research (15.07.2012)
Published in Clinical cancer research (15.07.2012)
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Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers
BELOUECHE-BABARI, Mounia, ARUNAN, Vaitha, LEACH, Martin O, CHUNG, Yuen-Li, TROY, Helen, TE POELE, Robert H, WONG TE FONG, Anne-Christine, ELIZABETH JACKSON, L, PAYNE, Geoffrey S, GRIFFITHS, John R, JUDSON, Ian R, WORKMAN, Paul
Published in Cancer research (Chicago, Ill.) (15.02.2012)
Published in Cancer research (Chicago, Ill.) (15.02.2012)
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Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal Cancer
Rao, Sheela, Welsh, Lyndsey, Cunningham, David, te-Poele, Robert H, Benson, Martin, Norman, Andrew, Saffery, Claire, Giddings, Ian, Workman, Paul, Clarke, Paul A
Published in Clinical colorectal cancer (01.03.2011)
Published in Clinical colorectal cancer (01.03.2011)
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Abstract 2998: Molecular and cellular effects of individual and combinatorial silencing of HSP90 paralogs
Powers, Marissa V., Te Poele, Robert H., Murphy, Ravindhi L., de Billy, Emmanuel, Clarke, Paul A., Workman, Paul
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 6441: Discovery of ARID1A loss as a patient biomarker for NXP800 - A developmental activator of the integrated stress response (ISR) and inhibitor of the HSF1 pathway in ovarian cancer
Poele, Robert H. te, Powers, Marissa, Sharp, Swee, de Billy, Emmanuel, Taskinen, Maria, Pellegrino, Loredana, Gowan, Sharon, Miah, Asadh, Hayes, Angela, Cheeseman, Matthew, Jones, Keith, Eccles, Suzanne, Raynaud, Florence, Clarke, Paul, Workman, Paul
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers
Beloueche-Babari, Mounia, Arunan, Vaitha, Troy, Helen, te Poele, Robert H, Fong, Anne-Christine Wong Te, Jackson, L Elizabeth, Payne, Geoffrey S, Griffiths, John R, Judson, Ian R, Workman, Paul, Leach, Martin O, Chung, Yuen-Li
Published in Cancer research (Chicago, Ill.) (22.12.2011)
Published in Cancer research (Chicago, Ill.) (22.12.2011)
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Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action distinct from AKT inhibitors
Yap, Timothy A., Walton, Michael I., Grimshaw, Kyla M., Poele, Robert H. te, Eve, Paul D., Valenti, Melanie R., de Haven Brandon, Alexis K., Martins, Vanessa, Zetterlund, Anna, Heaton, Simon P., Heinzmann, Kathrin, Jones, Paul S., Feltell, Ruth E., Reule, Matthias, Woodhead, Steven J., Davies, Thomas G., Lyons, John F., Raynaud, Florence I., Eccles, Suzanne A., Workman, Paul, Thompson, Neil T., Garrett, Michelle D.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways
Knowles, Helen J, te Poele, Robert H, Te Poole, Robert, Workman, Paul, Harris, Adrian L
Published in Biochemical pharmacology (28.02.2006)
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Published in Biochemical pharmacology (28.02.2006)
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Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance
Liu, Wai M., te Poele, Robert H., Joel, Simon P.
Published in JNCI : Journal of the National Cancer Institute (04.02.1998)
Published in JNCI : Journal of the National Cancer Institute (04.02.1998)
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