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Transferrin receptor in primary and metastatic breast cancer: Evaluation of expression and experimental modulation to improve molecular targeting
Fontana, Francesca, Esser, Alison K., Egbulefu, Christopher, Karmakar, Partha, Su, Xinming, Allen, John S., Xu, Yalin, Davis, Jennifer L., Gabay, Ariel, Xiang, Jingyu, Kwakwa, Kristin A., Manion, Brad, Bakewell, Suzanne, Li, Shunqiang, Park, Haeseong, Lanza, Gregory M., Achilefu, Samuel, Weilbaecher, Katherine N.
Published in PloS one (20.12.2023)
Published in PloS one (20.12.2023)
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Journal Article
RNA interference targeting apolipoprotein C-III with ARO-APOC3 in healthy volunteers mimics lipid and lipoprotein findings seen in subjects with inherited apolipoprotein C-III deficiency
Schwabe, C, Scott, R, Sullivan, D, Baker, J, Clifton, P, Hamilton, J, Given, B, San Martin, J, Melquist, S, Watts, G.F, Goldberg, I, Knowles, J.W, Hegele, R, Ballantyne, C
Published in European heart journal (01.11.2020)
Published in European heart journal (01.11.2020)
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Journal Article
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial
Narayan, Vivek, Barber-Rotenberg, Julie S., Jung, In-Young, Lacey, Simon F., Rech, Andrew J., Davis, Megan M., Hwang, Wei-Ting, Lal, Priti, Carpenter, Erica L., Maude, Shannon L., Plesa, Gabriela, Vapiwala, Neha, Chew, Anne, Moniak, Michael, Sebro, Ronnie A., Farwell, Michael D., Marshall, Amy, Gilmore, Joan, Lledo, Lester, Dengel, Karen, Church, Sarah E., Hether, Tyler D., Xu, Jun, Gohil, Mercy, Buckingham, Thomas H., Yee, Stephanie S., Gonzalez, Vanessa E., Kulikovskaya, Irina, Chen, Fang, Tian, Lifeng, Tien, Kyle, Gladney, Whitney, Nobles, Christopher L., Raymond, Hayley E., Hexner, Elizabeth O., Siegel, Donald L., Bushman, Frederic D., June, Carl H., Fraietta, Joseph A., Haas, Naomi B.
Published in Nature medicine (01.04.2022)
Published in Nature medicine (01.04.2022)
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Journal Article
1051-P: Selective Targeting of Angiopoietin-Like 3 (ANGPTL3) via the Second-Generation Antisense Oligonucleotide (ASO) ISIS-703802 (AKCEA-ANGPTL3-LRx) in Subjects with Familial Partial Lipodystrophy (FPLD)
FOSS-FREITAS, MARIA CRISTINA, AKINCI, BARIS, NEIDERT, ADAM H., HENCH, RITA P., SWAIDAN, MARIO, ORAL, ELIF A.
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
Reducing HIV infection in people who inject drugs is impossible without targeting recently-infected subjects: Erratum
Published in AIDS (London)
(13.03.2018)
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Journal Article
A phase I, open-label, multicenter, single-dose escalation and multi-dose study of a monoclonal antibody targeting CEACAM1 in subjects with selected advanced or recurrent malignancies
Shapira, Roni, Weber, Jeffrey S., Geva, Ravit, Sznol, Mario, Kluger, Harriet M., Wong, Deborah J.L., Liang, Bertrand C.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
P11.02 Targeting the Tumor Neovasculature in Lung Cancer: A Phase I Study of AMG 160 in Subjects With Non-Small Cell Lung Cancer
Blumenschein, G., Eggert, T., Shetty, A., Janát-Amsbury, M., Kouros-Mehr, H., Bhatia, A.S., Gupta, V., Tiso, S., Salvati, M., Boyer, M.
Published in Journal of thoracic oncology (01.10.2021)
Published in Journal of thoracic oncology (01.10.2021)
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Journal Article
Advanced drug delivery and targeting technologies for the ocular diseases
Barar, Jaleh, Aghanejad, Ayuob, Fathi, Marziyeh, Omidi, Yadollah
Published in Bioimpacts (01.01.2016)
Published in Bioimpacts (01.01.2016)
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Journal Article
An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level
Bauer, Daniel E., Kamran, Sophia C., Lessard, Samuel, Xu, Jian, Fujiwara, Yuko, Lin, Carrie, Shao, Zhen, Canver, Matthew C., Smith, Elenoe C., Pinello, Luca, Sabo, Peter J., Vierstra, Jeff, Voit, Richard A., Yuan, Guo-Cheng, Porteus, Matthew H., Stamatoyannopoulos, John A., Lettre, Guillaume, Orkin, Stuart H.
Published in Science (American Association for the Advancement of Science) (11.10.2013)
Published in Science (American Association for the Advancement of Science) (11.10.2013)
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Journal Article
TNB585.001: A multicenter, phase 1, open-label, dose-escalation and expansion study of tnb-585, a bispecific T-cell engager targeting PSMA in subjects with metastatic castrate resistant prostate cancer
Buelow, Ben, Dalvi, Pranjali, Dang, Kevin, Patel, Ashwin, Johal, Kiran, Pham, Duy, Panchal, Shailee, Liu, Yvonne, Fong, Lawrence, Sartor, A. Oliver, McKean, Meredith, Schellenberger, Ute, Iyer, Suhasini
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
SAT0222 BIIB059, a monoclonal antibody targeting BDCA2, shows evidence of biological activity and early clinical proof of concept in subjects with active cutaneous le
Furie, R, Werth, VP, Merola, JF, Reynolds, TL, Stevenson, L, Wang, W, Smirnakis, K, Barbey, C, Musselli, C, Werneburg, B, Rabah, D, Franchimont, N
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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Journal Article
First-In-Human Study on Pharmacokinetics, Safety, and Tolerability of Single and Multiple Escalating Doses of Hepenofovir, a Novel Hepatic Targeting Prodrug of Tenofovir in Healthy Chinese Subjects
Zhang, Hong, Gao, Lei, Lou, Jinfeng, Wu, Min, Chen, Hong, Yang, Lizhi, Liu, Jingrui, Zhu, Xiaoxue, Li, Xiaojiao, Li, Cuiyun, Wang, Meng, Liu, Chengjiao, Guo, Weibo, Wang, Yuan, Gao, Zhongqiang, Han, Lei, Wang, Daidi, Jin, Weili, Ding, Yanhua
Published in Frontiers in Pharmacology (19.05.2022)
Published in Frontiers in Pharmacology (19.05.2022)
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Journal Article