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Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial
Pratt, Arthur G, Siebert, Stefan, Cole, Michael, Stocken, Deborah D, Yap, Christina, Kelly, Stephen, Shaikh, Muddassir, Cranston, Amy, Morton, Miranda, Walker, Jenn, Frame, Sheelagh, Ng, Wan-Fai, Buckley, Christopher D, McInnes, Iain B, Filer, Andrew, Isaacs, John D
Published in The Lancet. Rheumatology (01.05.2021)
Published in The Lancet. Rheumatology (01.05.2021)
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The Effect of SHH-Gli Signaling Pathway on the Synovial Fibroblast Proliferation in Rheumatoid Arthritis
Qin, Suping, Sun, Dexu, Li, Hui, Li, Xiangyang, Pan, Wei, Yan, Chao, Tang, Renxian, Liu, Xiaomei
Published in Inflammation (01.04.2016)
Published in Inflammation (01.04.2016)
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AB0356 TARGETING THE RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLAST VIA CYCLIN DEPENDENT KINASE INHIBITION (TRAFIC): A PHASE 1B STUDY TO DETERMINE THE MAXIMUM TOLERATED DOSE OF SELICICLIB FOR REPURPOSING IN RHEUMATOID ARTHRITIS
Pratt, A., Siebert, S., Cole, M., Stocken, D., Kelly, S., Shaikh, M., Cranston, A., Morton, M., Walker, J., Frame, S., Ng, W. F., Buckley, C., Mcinnes, I., Filer, A., Isaacs, J. D.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Actin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis
Vasilopoulos, Y, Gkretsi, V, Armaka, M, Aidinis, V, Kollias, G
Published in Annals of the rheumatic diseases (01.11.2007)
Published in Annals of the rheumatic diseases (01.11.2007)
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Mechanical Stress Induces Sodium Entry and Osmoprotective Responses in Murine Synovial Fibroblasts
Proff, Annemarie, Nazet, Ute, Schröder, Agnes, Jantsch, Jonathan
Published in Cells (Basel, Switzerland) (01.03.2024)
Published in Cells (Basel, Switzerland) (01.03.2024)
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Differential Expression Profiles of the Transcriptome and miRNA Interactome in Synovial Fibroblasts of Rheumatoid Arthritis Revealed by Next Generation Sequencing
Tseng, Chia-Chun, Wu, Ling-Yu, Tsai, Wen-Chan, Ou, Tsan-Teng, Wu, Cheng-Chin, Sung, Wan-Yu, Kuo, Po-Lin, Yen, Jeng-Hsien
Published in Diagnostics (Basel) (18.08.2019)
Published in Diagnostics (Basel) (18.08.2019)
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Th17 lymphocyte‐dependent degradation of joint cartilage by synovial fibroblasts in a humanized mouse model of arthritis and reversal by secukinumab
Margheri, Francesca, Maggi, Laura, Biagioni, Alessio, Chillà, Anastasia, Laurenzana, Anna, Bianchini, Francesca, Bani, Daniele, Capone, Manuela, Mazzoni, Alessio, Rossi, Maria Caterina, Liotta, Francesco, Cosmi, Lorenzo, Giani, Teresa, Cimaz, Rolando, Fibbi, Gabriella, Annunziato, Francesco, Del Rosso, Mario
Published in European journal of immunology (01.01.2021)
Published in European journal of immunology (01.01.2021)
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High glucose induces vascular endothelial growth factor production in human synovial fibroblasts through reactive oxygen species generation
Tsai, Chun-Hao, Chiang, Yi-Chun, Chen, Hsien-Te, Huang, Po-Hao, Hsu, Horng-Chaung, Tang, Chih-Hsin
Published in Biochimica et biophysica acta (01.03.2013)
Published in Biochimica et biophysica acta (01.03.2013)
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LncRNA RNA XIST binding to GATA1 contributes to rheumatoid arthritis through its effects on proliferation of synovial fibroblasts and angiogenesis via regulation of CCN6
Yu, Beijia, Chen, Yong, Chen, Ensheng, Zuo, Fangfang, Yuan, Yi, Zhao, Xiaofeng, Xiao, Changhong
Published in Molecular immunology (01.01.2023)
Published in Molecular immunology (01.01.2023)
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Modulation by retinoic acid and corticosteroids of collagenase production by rabbit synovial fibroblasts treated with phorbol myristate acetate or poly(ethylene glycol)
Brinckerhoff, Constance E., Harris, Edward D.
Published in Biochimica et biophysica acta (05.11.1981)
Published in Biochimica et biophysica acta (05.11.1981)
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AB0097 Individual functions of the histone-acetyltransferases cbp and p300 in rheumatoid arthritis synovial fibroblasts
Lee, G., Kolling, C., Distler, O., Ospelt, C., Klein, K.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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SAT0066 The long noncoding rna (LNCRNA) hottip is a master regulator of cell cycle in hand synovial fibroblasts in arthritis
Frank Bertoncelj, M., Masterson, T., Karouzakis, E., Kolling, C., Filer, A., Buckley, C.D., Gay, S., Distler, O., Ospelt, C.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival
Benito-Miguel, Marta, García-Carmona, Yolanda, Balsa, Alejandro, Bautista-Caro, María-Belén, Arroyo-Villa, Irene, Cobo-Ibáñez, Tatiana, Bonilla-Hernán, María Gema, de Ayala, Carlos Pérez, Sánchez-Mateos, Paloma, Martín-Mola, Emilio, Miranda-Carús, María-Eugenia
Published in PloS one (09.07.2012)
Published in PloS one (09.07.2012)
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OP0326 Epigenetically-driven distal expression of the lncrna hottip shapes inflammatory, adhesive and proliferative characteristics of hand synovial fibroblasts in arthritis
Bertoncelj, M Frank, Karouzakis, E, Klein, K, Bratus, A, Kolling, C, Distler, O, Filer, A, Gay, RE, Buckley, CD, Gay, S, Ospelt, C
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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